There are 4 ways to get from Chicago to Knoxville by train (Amtrak), car, plane, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain Southwest Chief / ...
2h 44m$71–130Drive 184.2 mi
cheapest- Drive from Chicago to Knoxvillecar 184.2 mi
3h 41m$34–49Fly to Quad City International Airport, taxi
- Fly from Chicago O'Hare International Airport (ORD) to Quad City International Airport (MLI)plane ORD - MLI
- Take the taxi from Moline-Airport-MLI to Knoxvilletaxi
3h 46m$168–435Fly to Burlington Municipal Airport, taxi
- Fly from Chicago O'Hare International Airport (ORD) to Burlington Municipal Airport (BRL)plane ORD - BRL
- Take the taxi from Burlington Municipal Airport (BRL) to Knoxvilletaxi
4h 16m$178–285
Chicago O'Hare International Airport (ORD) to Quad City International Airport (MLI) flights
Questions & Answers
The cheapest way to get from Chicago to Knoxville is to drive which costs $30 - $50 and takes 3h 41m.
The fastest way to get from Chicago to Knoxville is to train which takes 2h 44m and costs $70 - $130.
No, there is no direct train from Chicago station to Knoxville station. However, there are services departing from Chicago Union Station and arriving at Galesburg Amtrak Station via . The journey, including transfers, takes approximately 2h 44m.
The distance between Chicago and Knoxville is 168 miles. The road distance is 185.3 miles.
The best way to get from Chicago to Knoxville without a car is to train which takes 2h 44m and costs $70 - $130.
It takes approximately 2h 44m to get from Chicago to Knoxville, including transfers.
Chicago to Knoxville train services, operated by Amtrak, depart from Chicago Union Station.
Chicago to Knoxville train services, operated by Amtrak, arrive at Galesburg Amtrak Station.
Yes, the driving distance between Chicago to Knoxville is 185 miles. It takes approximately 3h 41m to drive from Chicago to Knoxville.
There are 11+ hotels available in Knoxville.
What companies run services between Chicago, IL, USA and Knoxville, IL, USA?
Amtrak operates a train from Chicago Union Station to Galesburg Amtrak Station 4 times a day. Tickets cost $50–110 and the journey takes 2h 36m.
- Website
- united.com
Flights from Chicago O'Hare International Airport to Quad City International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- $35–270
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Quad City International Airport
- Ave. Duration
- 1h 9m
- When
- Every day
- Estimated price
- $35–270
- Website
- contouraviation.com
Flights from Chicago O'Hare International Airport to Burlington Municipal Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- $55–130
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to Galesburg Amtrak Station
- Ave. Duration
- 2h 36m
- Frequency
- 4 times a day
- Estimated price
- $50–110
- Website
- Amtrak
- Ave. Duration
- 1h 1m
- Estimated price
- $120–160
Dana's Cabs
- Phone
- +1 563-323-2227
- Website
- danascabs.com
Good to Go Taxi Cab Service
- Phone
- +1 563-424-2039
- Website
- goodtogotaxi.com
Larry's Cab
- Phone
- +1 563-388-7179
Want to know more about travelling around United States
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