There are 6 ways to get from Chicago to Lancaster by plane, train (Amtrak), bus, car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Chicago Midway International Airport
best- Fly from Chicago Midway International Airport (MDW) to Buffalo Niagara International Airport (BUF)plane MDW - BUF
3h 11m$184–400Bus
cheapest- Take the bus from Chicago to Clevelandbus Chicago
- Take the bus from Cleveland, OH to Buffalo, NYbus Cinncinati,OH-Buffalo
13h 8m$54–141Train (Amtrak)
- Take the train from Chicago Union Station to Buffalo Depew Stationtrain Lake Shore Limited
10h 29m$182–363Drive 536.7 mi
- Drive from Chicago to Lancastercar 536.7 mi
9h 11m$98–142Fly from Chicago O'Hare International Airport
- Fly from Chicago O'Hare International Airport (ORD) to Buffalo Niagara International Airport (BUF)plane ORD - BUF
3h 36m$194–330Bus via Brook Park (Greyhound)
- Take the bus from Chicago Bus Station to Cleveland Bus Stationbus Greyhound US0164
- Take the bus from Cleveland Bus Station to Buffalobus Greyhound US0171 / ...
13h 43m$84–161
Chicago to Lancaster by bus
Questions & Answers
The cheapest way to get from Chicago to Lancaster is to bus via Brook Park which costs $80 - $170 and takes 13h 43m.
The fastest way to get from Chicago to Lancaster is to fly which takes 3h 11m and costs $180 - $400.
No, there is no direct bus from Chicago to Lancaster. However, there are services departing from Chicago and arriving at Pleasant Avenue & Rite Aid via Cleveland, OH and Ellicott Street & MTC Static. The journey, including transfers, takes approximately 13h 8m.
No, there is no direct train from Chicago station to Lancaster station. However, there are services departing from Chicago Union Station and arriving at Buffalo Depew Station via . The journey, including transfers, takes approximately 10h 29m.
The distance between Chicago and Lancaster is 486 miles. The road distance is 539.8 miles.
The best way to get from Chicago to Lancaster without a car is to train which takes 10h 29m and costs $180 - $370.
It takes approximately 3h 11m to get from Chicago to Lancaster, including transfers.
Chicago to Lancaster bus services, operated by Barons Bus, depart from Chicago station.
Chicago to Lancaster train services, operated by Amtrak, depart from Chicago Union Station.
The best way to get from Chicago to Lancaster is to fly which takes 3h 11m and costs $180 - $400. Alternatively, you can train, which costs $180 - $370 and takes 10h 29m, you could also bus, which costs $50 - $150 and takes 13h 8m.
What companies run services between Chicago, IL, USA and Lancaster, NY, USA?
Southwest Airlines and Delta fly from Chicago Midway International Airport (MDW) to Buffalo Niagara International Airport (BUF) 4 times a day. Alternatively, Amtrak operates a train from Chicago Union Station to Buffalo Depew Station twice daily. Tickets cost $170–350 and the journey takes 10h 23m.
- Website
- southwest.com
Flights from Chicago Midway International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $110–650
- Website
- united.com
Flights from Chicago O'Hare International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 47m
- When
- Every day
- Estimated price
- $85–500
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 48m
- When
- Every day
- Estimated price
- $85–500
- Website
- delta.com
Flights from Chicago Midway International Airport to Buffalo Niagara International Airport via Detroit
- Ave. Duration
- 3h 27m
- When
- Every day
- Estimated price
- $110–650
Flights from Chicago O'Hare International Airport to Buffalo Niagara International Airport via Detroit
- Ave. Duration
- 3h 31m
- When
- Every day
- Estimated price
- $85–500
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Buffalo Depew Station
- Ave. Duration
- 10h 23m
- Frequency
- Twice daily
- Estimated price
- $170–350
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 888-378-3823
- [email protected]
- Website
- baronsbus.com
Bus from Chicago to Cleveland
- Ave. Duration
- 6h 55m
- Frequency
- Once daily
- Estimated price
- $30–80
- Website
- https://baronsbus.com
Bus from Cleveland, OH to Buffalo, NY
- Ave. Duration
- 3h 10m
- Frequency
- Once daily
- Estimated price
- $18–60
- Website
- https://baronsbus.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Chicago Bus Station to Cleveland Bus Station
- Ave. Duration
- 7h 10m
- Frequency
- Twice daily
- Estimated price
- $50–100
- Website
- https://www.greyhound.com/
Bus from Cleveland Bus Station to Buffalo
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- $30–60
- Website
- https://www.greyhound.com/
Want to know more about travelling around United States
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More Questions & Answers
Chicago to Lancaster bus services, operated by Barons Bus, arrive at Cleveland station.
Lancaster is 1h ahead of Chicago. It is currently 12:34 AM in Chicago and 1:34 AM in Lancaster.
Chicago to Lancaster train services, operated by Amtrak, arrive at Buffalo Depew Station.
Yes, the driving distance between Chicago to Lancaster is 540 miles. It takes approximately 9h 11m to drive from Chicago to Lancaster.
Book your Chicago to Lancaster train tickets online with Omio.
There are 239+ hotels available in Lancaster.