There are 6 ways to get from Chicago to Lancaster by plane, train (Amtrak), bus (Flixbus), car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Chicago O'Hare International Airport (ORD) to Lancaster (LNS)plane ORD - LNS
4h 4m$76–337Train via Pittsburgh (Amtrak)
- Take the train from Chicago Union Station to Pittsburgh Amtrak Stationtrain Floridian
- Take the train from Pittsburgh Amtrak Station to Elizabethtown Amtrak Stationtrain Pennsylvanian
18h 13m$402–622Bus (Flixbus)
- Take the bus from Chicago Bus Station to Harrisburg Bus Stationbus FlixBus N2640 / ...
19h 6m$132–196Drive 691.8 mi
- Drive from Chicago to Lancastercar 691.8 mi
11h 23m$119–171Bus via Baltimore (Greyhound)
- Take the bus from Chicago Bus Station to Baltimore Downtown Bus Stationbus Greyhound US0164
- Take the bus from Baltimore Downtown Bus Station to Harrisburg Bus Stationbus Greyhound US0430 / ...
25h 51m$176–266Train (Amtrak)
- Take the train from Chicago Union Station to 30th Street Stationtrain Cardinal
- Take the train from 30th Street Station to Elizabethtown Amtrak Stationtrain Keystone Service / ...
30h 22m$620–957
Chicago to Lancaster by train and bus (Amtrak)
Comparing Your Travel Options
The cheapest way to get from Chicago to Lancaster is to drive which costs $110 - $180 and takes 11h 23m.
The fastest way to get from Chicago to Lancaster is to fly which takes 4h 4m and costs $75 - $340.
No, there is no direct bus from Chicago station to Lancaster. However, there are services departing from Chicago Bus Station and arriving at W. Chestnut & Water St. via AMTRAK ETown. The journey, including transfers, takes approximately 19h 6m.
No, there is no direct train from Chicago station to Lancaster station. However, there are services departing from Chicago Union Station and arriving at Elizabethtown Amtrak Station via Pittsburgh Amtrak Station. The journey, including transfers, takes approximately 18h 13m.
The distance between Chicago and Lancaster is 646 miles. The road distance is 695.8 miles.
The best way to get from Chicago to Lancaster without a car is to train via Pittsburgh which takes 18h 13m and costs $400 - $650.
It takes approximately 4h 4m to get from Chicago to Lancaster, including transfers.
Chicago to Lancaster bus services, operated by Flixbus USA, depart from Chicago Bus Station.
Chicago to Lancaster train services, operated by Amtrak, depart from Chicago Union Station.
The best way to get from Chicago to Lancaster is to fly which takes 4h 4m and costs $75 - $340. Alternatively, you can train via Pittsburgh, which costs $400 - $650 and takes 18h 13m, you could also bus, which costs $130 - $200 and takes 19h 6m.
What companies run services between Chicago, IL, USA and Lancaster, PA, USA?
United Airlines flies from Chicago O'Hare International Airport (ORD) to Lancaster (LNS) twice daily. Alternatively, you can take a train from Chicago Union Station to W. Chestnut & Water St. via Pittsburgh Amtrak Station, Elizabethtown Amtrak Station, and AMTRAK ETown in around 18h 13m.
- Website
- united.com
Flights from Chicago O'Hare International Airport to Lancaster
- Ave. Duration
- 2h 6m
- When
- Every day
- Estimated price
- $55–310
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to Pittsburgh Amtrak Station
- Ave. Duration
- 9h 25m
- Frequency
- Once daily
- Estimated price
- $260–410
- Website
- Amtrak
Train from Pittsburgh Amtrak Station to Elizabethtown Amtrak Station
- Ave. Duration
- 5h 52m
- Frequency
- Once daily
- Estimated price
- $140–220
- Website
- Amtrak
Train from Chicago Union Station to 30th Street Station
- Ave. Duration
- 25h 56m
- Frequency
- 3 times a week
- Estimated price
- $550–900
- Website
- Amtrak
Train from 30th Street Station to Elizabethtown Amtrak Station
- Ave. Duration
- 1h 32m
- Frequency
- Every 2 hours
- Estimated price
- $45–75
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Chicago Bus Station to Harrisburg Bus Station
- Ave. Duration
- 15h 55m
- Frequency
- 3 times a day
- Estimated price
- $120–190
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Chicago Bus Station to Baltimore Downtown Bus Station
- Ave. Duration
- 17h 45m
- Frequency
- 4 times a day
- Estimated price
- $140–210
- Website
- Greyhound
Bus from Baltimore Downtown Bus Station to Harrisburg Bus Station
- Ave. Duration
- 3h 55m
- Frequency
- Once daily
- Estimated price
- $27–45
- Website
- Greyhound
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Chicago to Lancaster bus services, operated by Flixbus USA, arrive at Harrisburg Bus Station.
Lancaster is 1h ahead of Chicago. It is currently 12:10 PM in Chicago and 1:10 PM in Lancaster.
Chicago to Lancaster train services, operated by Amtrak, arrive at Pittsburgh Amtrak Station.
Yes, the driving distance between Chicago to Lancaster is 696 miles. It takes approximately 11h 23m to drive from Chicago to Lancaster.
Book your Chicago to Lancaster train tickets online with Omio.
There are 250+ hotels available in Lancaster.






