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How to get fromChicago to Lexington Bus Stopby plane, bus, bus (Flixbus, Greyhound), train, car, or bus (Greyhound)

Find Transport to Lexington Bus Stop

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There are 6 ways to get from Chicago to Lexington Bus Stop by plane, bus, bus (Flixbus, Greyhound), train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Chicago O'Hare International Airport, line 4 bus

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Blue Grass Airport (LEX)plane plane ORD - LEX
    2. Take the bus from Transit Center to Walmart @ Northparkbus bus
    5h 34m
    $44–297

  2. Bus

    1. Take the bus from Chicago Bus Station to Cincinnatibus bus FlixBus 2514 / ...
    2. Take the bus from Cincinnati Bus Station to Lexington Bus Stopbus bus Greyhound US0110
    9h 40m
    $59–118

  3. Train, bus

    1. Take the train from Chicago Union Station to Indianapolistrain train
    2. Take the bus from Indianapolis, IN to Greyhound Station Cincinnatibus bus
    3. Take the bus from Cincinnati Bus Station to Lexington Bus Stopbus bus
    11h 29m
    $75–187

  4. Drive  355.5 mi

    1. Drive from Chicago to Lexington Bus Stopcar car 355.5 mi
    6h 22m
    $65–94

  5. Fly from Chicago Midway International Airport

    1. Fly from Chicago Midway International Airport (MDW) to Blue Grass Airport (LEX)plane plane MDW - LEX
    7h 53m
    $80–457

  6. Bus via Lima

    1. Take the bus from Chicago to Limabus bus Bsb 22
    2. Take the bus from Lima Regional Transit Authority to Lexington Bus Stopbus bus Greyhound US0110
    12h 15m
    $54–118

Chicago to Lexington Bus Stop by bus

Calendar7Weekly Buses
Duration9h 40mAverage Duration
Ticket$59Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Chicago to Lexington Bus Stop.ExpandLaunch map view
  • Distance: 353.5 mi
  • Duration: 5h 34m

What companies run services between Chicago, IL, USA and Lexington Bus Stop, KY, USA?

You can take a bus from Chicago Bus Station to Lexington Bus Stop via University of Cincinnati, Greyhound Station Cincinnati, and Cincinnati Bus Station in around 9h 40m. Alternatively, Delta and Southwest Airlines fly from Chicago Midway International Airport (MDW) to Blue Grass Airport (LEX) every 4 hours.

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