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How to get fromChicago to Lexingtonby plane, taxi, bus (Greyhound, Flixbus), car, bus, bus (Greyhound, Amtrak), or train

Find Transport to Lexington

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There are 10 ways to get from Chicago to Lexington by plane, taxi, bus (Greyhound, Flixbus), car, bus, bus (Greyhound, Amtrak), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Mc Kellar-Sipes Regional Airport, taxi

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Mc Kellar-Sipes Regional Airport (MKL)plane plane ORD - MKL
    2. Take the taxi from Mc Kellar-Sipes Regional Airport (MKL) to Lexingtontaxi taxi
    4h 18m
    $198–375

  2. Fly Chicago O'Hare International Airport to Barkley Regional Airport, drive

    cheapest
    1. Fly from Chicago O'Hare International Airport (ORD) to Barkley Regional Airport (PAH)plane plane ORD - PAH
    2. Drive from Barkley Regional Airport (PAH) to Lexingtoncar car
    5h 54m
    $68–345

  3. Bus

    1. Take the bus from Chicago Bus Station to Memphis Bus Stationbus bus Greyhound US0125
    2. Take the bus from Memphis Bus Station to Jacksonbus bus Greyhound US0135 / ...
    12h 23m
    $166–268

  4. Drive 478.8 mi

    1. Drive from Chicago to Lexingtoncar car 478.8 mi
    8h 32m
    $88–127

  5. Fly Chicago Midway International Airport to Nashville, bus

    1. Fly from Chicago Midway International Airport (MDW) to Nashville (BNA)plane plane MDW - BNA
    2. Take the bus from Nashville Bus Station to Jacksonbus bus
    7h 12m
    $164–572

  6. Fly Chicago O'Hare International Airport to Nashville, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Nashville (BNA)plane plane ORD - BNA
    2. Take the bus from Nashville Bus Station to Jacksonbus bus
    7h 34m
    $194–422

  7. Bus, taxi

    1. Take the bus from Chicago to Tornado Bus Co - West Memphisbus bus
    2. Take the bus from Tornado Bus Co - West Memphis to El Mezcal Grocery - Jackson, TNbus bus
    3. Take the taxi from El Mezcal Grocery - Jackson, TN to Lexingtontaxi taxi
    13h 25m
    $220–458

  8. Bus via Nashville

    1. Take the bus from Chicago Bus Station to Nashville Bus Stationbus bus Greyhound US0100
    2. Take the bus from Nashville Bus Station to Jacksonbus bus Greyhound US0135 / ...
    13h 28m
    $162–262

  9. Bus via Nashville #2

    1. Take the bus from Chicago Train Station to Nashville Bus Stationbus bus Greyhound US0100
    2. Take the bus from Nashville Bus Station to Jacksonbus bus Greyhound US0135 / ...
    13h 43m
    $145–210

  10. Train, bus

    1. Take the train from Chicago Union Station to Carbondaletrain train
    2. Take the bus from Carbondale Intermodal Station to Nashville Bus Stationbus bus
    3. Take the bus from Nashville Bus Station to Jacksonbus bus
    13h 58m
    $219–389

Chicago O'Hare International Airport (ORD) to Mc Kellar-Sipes Regional Airport (MKL) flights

Calendar6Weekly Planes
Duration1h 50mAverage Duration
Ticket$97Cheapest Price
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Questions & Answers

Map of how to get from Chicago to Lexington.ExpandLaunch map view
  • Distance: 496.9 mi
  • Duration: 4h 18m

What companies run services between Chicago, IL, USA and Lexington, TN, USA?

You can take a bus from Chicago Bus Station to Lexington via Memphis Bus Station and Jackson in around 12h 23m.

Airlines
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