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How to get fromChicago to Louisianaby train, taxi, car, plane, or shuttle

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There are 7 ways to get from Chicago to Louisiana by train, taxi, car, plane, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, taxi

    best
    1. Take the train from Chicago Union Station to Quincy Amtrak Stationtrain train Carl Sandburg / ...
    2. Take the taxi from Quincy Amtrak Station to Louisianataxi taxi
    5h 30m
    $196–331

  2. Drive 286.7 mi

    cheapest
    1. Drive from Chicago to Louisianacar car 286.7 mi
    5h 1m
    $53–76

  3. Fly Chicago O'Hare International Airport to Quincy Regional Airport, taxi

    1. Fly from Chicago O'Hare International Airport (ORD) to Quincy Regional Airport (UIN)plane plane ORD - UIN
    2. Take the taxi from Quincy Regional Airport (UIN) to Louisianataxi taxi
    4h 29m
    $152–255

  4. Fly Chicago O'Hare International Airport to Columbia Regional Airport, shuttle

    1. Fly from Chicago O'Hare International Airport (ORD) to Columbia Regional Airport (COU)plane plane ORD - COU
    2. Take a shuttle bus from Columbia to Louisiana, MOshuttle bus
    5h 59m
    $102–376

  5. Fly Chicago O'Hare International Airport to Lambert–St. Louis International Airport, shuttle

    1. Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane plane ORD - STL
    2. Take a shuttle bus from St. Louis to Bowling Green, Moshuttle bus
    6h 19m
    $320–717

  6. Fly Chicago Midway International Airport to Lambert–St. Louis International Airport, shuttle

    1. Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane plane MDW - STL
    2. Take a shuttle bus from St. Louis to Bowling Green, Moshuttle bus
    6h 3m
    $80–517

  7. Fly Chicago O'Hare International Airport to Burlington Municipal Airport, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Burlington Municipal Airport (BRL)plane plane ORD - BRL
    2. Drive from Burlington Municipal Airport (BRL) to Louisianacar car
    5h 56m
    $74–170

Chicago O'Hare International Airport (ORD) to Quincy Regional Airport (UIN) flights

Calendar7Weekly Planes
Duration1h 20mAverage Duration
Ticket$55Cheapest Price
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Questions & Answers

Map of how to get from Chicago to Louisiana.ExpandLaunch map view
  • Distance: 355.3 mi
  • Duration: 5h 30m

What companies run services between Chicago, IL, USA and Louisiana, MO, USA?

There is no direct connection from Chicago to Louisiana. However, you can take the train to Quincy Amtrak Station then take the taxi to Louisiana. Alternatively, you can drive from Chicago to Louisiana in around 5h 1m.

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