There are 6 ways to get from Chicago to Louisville by bus, taxi, train, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, taxi (Greyhound)
best- Take the bus from Chicago Bus Station to Effinghambus Greyhound US0125
- Take the taxi from Effingham to Louisvilletaxi
4h 4m$92–136Drive 234.6 mi
cheapest- Drive from Chicago to Louisvillecar 234.6 mi
4h 7m$43–62Train, taxi (Amtrak)
- Take the train from Chicago Union Station to Effingham Stationtrain Saluki / ...
- Take the taxi from Effingham Station to Louisvilletaxi
4h 19m$119–201Fly to Evansville, drive
- Fly from Chicago O'Hare International Airport (ORD) to Evansville (EVV)plane ORD - EVV
- Drive from Evansville (EVV) to Louisvillecar
5h 10m$64–321Bus, taxi via California & 35th Street
- Take the bus from Chicago to Lupita's Grocery - Effinghambus Chicago
- Take the taxi from Lupita's Grocery - Effingham to Louisvilletaxi
5h 41m$112–232Fly to University Of Illinois Willard Airport, train, taxi
- Fly from Chicago O'Hare International Airport (ORD) to University Of Illinois Willard Airport (CMI)plane ORD - CMI
- Take the train from Champaign-Urbana to Effingham Stationtrain
- Take the taxi from Effingham Station to Louisvilletaxi
5h 45m$134–408
Chicago O'Hare International Airport (ORD) to Evansville (EVV) flights
Questions & Answers
The cheapest way to get from Chicago to Louisville is to drive which costs $40 - $65 and takes 4h 7m.
The fastest way to get from Chicago to Louisville is to bus and taxi which takes 4h 4m and costs $90 - $140.
The distance between Chicago and Louisville is 238 miles. The road distance is 236 miles.
The best way to get from Chicago to Louisville without a car is to bus and taxi which takes 4h 4m and costs $90 - $140.
It takes approximately 4h 4m to get from Chicago to Louisville, including transfers.
Yes, the driving distance between Chicago to Louisville is 236 miles. It takes approximately 4h 7m to drive from Chicago to Louisville.
There are three+ hotels available in Louisville.
What companies run services between Chicago, IL, USA and Louisville, IL, USA?
There is no direct connection from Chicago to Louisville. However, you can take the bus to Effingham then take the taxi to Louisville. Alternatively, you can take the train to Effingham Station then take the taxi to Louisville.
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Evansville
- Ave. Duration
- 1h 22m
- When
- Every day
- Estimated price
- $45–290
Flights from Chicago O'Hare International Airport to University Of Illinois Willard Airport
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- $35–260
- Website
- united.com
Flights from Chicago O'Hare International Airport to University Of Illinois Willard Airport
- Ave. Duration
- 1h 9m
- When
- Every day
- Estimated price
- $35–260
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Effingham Station
- Ave. Duration
- 3h 41m
- Frequency
- 3 times a day
- Estimated price
- $60–140
- Website
- https://www.amtrak.com/home.html
Train from Champaign-Urbana to Effingham Station
- Ave. Duration
- 1h 7m
- Frequency
- 3 times a day
- Estimated price
- $23–50
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Chicago Bus Station to Effingham
- Ave. Duration
- 3h 25m
- Frequency
- Once daily
- Estimated price
- $30–65
- Website
- https://www.greyhound.com/
- Phone
- +1 888 358 6762
- [email protected]
- Website
- tornadobus.com
Bus from Chicago to Lupita's Grocery - Effingham
- Ave. Duration
- 3h 25m
- Frequency
- Once daily
- Estimated price
- $55–160
- Schedules at
- tornadobus.com
- Adults 11-59
- $55–160
- Ave. Duration
- 38 min
- Estimated price
- $55–75
Want to know more about travelling around United States
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