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How to get fromChicago to Manchesterby plane, car, bus (Greyhound), bus, bus (Flixbus, Greyhound), or train

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There are 7 ways to get from Chicago to Manchester by plane, car, bus (Greyhound), bus, bus (Flixbus, Greyhound), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Mcghee Tyson Airport, drive

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Mcghee Tyson Airport (TYS)plane plane ORD - TYS
    2. Drive from Mcghee Tyson Airport (TYS) to Manchestercar car
    5h 59m
    $126–640

  2. Drive 449.7 mi

    cheapest
    1. Drive from Chicago to Manchestercar car 449.7 mi
    8h
    $83–119

  3. Bus

    1. Take the bus from Chicago Bus Station to Lexington Bus Stopbus bus Greyhound US0120
    2. Take the bus from Lexington Bus Stop to Londonbus bus Greyhound US0110
    11h 59m

  4. Fly to Tri-Cities Regional Tn/Va Airport, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Tri-Cities Regional Tn/Va Airport (TRI)plane plane ORD - TRI
    2. Drive from Tri-Cities-Regional-Airport-TRI to Manchestercar car
    6h 52m
    $100–460

  5. Fly to Blue Grass Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Blue Grass Airport (LEX)plane plane ORD - LEX
    2. Take the bus from Lexington Bus Stop to Londonbus bus
    8h 37m
    $176–761

  6. Bus via Dayton

    1. Take the bus from Chicago Bus Station to Dayton Trotwood Bus Stationbus bus FlixBus 2511 / ...
    2. Take the bus from Dayton Trotwood Bus Station to Londonbus bus Greyhound US0110
    12h 24m
    $118–220

  7. Train, bus

    1. Take the train from Chicago Union Station to Indianapolistrain train
    2. Take the bus from Indianapolis Union Station to Lexington Bus Stopbus bus
    3. Take the bus from Lexington Bus Stop to Londonbus bus
    12h 48m

Chicago O'Hare International Airport (ORD) to Mcghee Tyson Airport (TYS) flights

Calendar75Weekly Planes
Duration2h 58mAverage Duration
Ticket$108Cheapest Price
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Questions & Answers

Map of how to get from Chicago to Manchester.ExpandLaunch map view
  • Distance: 623.1 mi
  • Duration: 5h 59m

What companies run services between Chicago, IL, USA and Manchester, KY, USA?

You can take a bus from Chicago Bus Station to Manchester via Lexington Bus Stop and London in around 11h 59m.

Airlines
Train operators
Bus operators

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