There are 5 ways to get from Chicago to Mendon by train (Amtrak), car, plane, shuttle, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from Chicago Union Station to Quincy Amtrak Stationtrain Carl Sandburg / ...
4h 39m$122–230Drive 270 mi
cheapest- Drive from Chicago to Mendoncar 270 mi
5h 40m$50–72Fly Chicago O'Hare International Airport to Burlington Municipal Airport, drive
- Fly from Chicago O'Hare International Airport (ORD) to Burlington Municipal Airport (BRL)plane ORD - BRL
- Drive from Burlington Municipal Airport (BRL) to Mendoncar
4h 35m$68–153Fly Chicago O'Hare International Airport to Kirksville Regional Airport, drive
- Fly from Chicago O'Hare International Airport (ORD) to Kirksville Regional Airport (IRK)plane ORD - IRK
- Drive from Kirksville Regional Airport (IRK) to Mendoncar
5h 25m$82–218Fly Chicago Midway International Airport to Lambert–St. Louis International Airport, shuttle, taxi
- Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane MDW - STL
- Take a shuttle bus from St. Louis to Palmyra
- Take the taxi from Palmyra to Mendontaxi
6h 46m$164–625
Chicago O'Hare International Airport (ORD) to Burlington Municipal Airport (BRL) flights
Questions & Answers
The cheapest way to get from Chicago to Mendon is to drive which costs $45 - $75 and takes 5h 40m.
The fastest way to get from Chicago to Mendon is to fly and drive which takes 4h 35m and costs $65 - $160.
No, there is no direct train from Chicago station to Mendon station. However, there are services departing from Chicago Union Station and arriving at Quincy Amtrak Station via . The journey, including transfers, takes approximately 4h 39m.
The distance between Chicago and Mendon is 322 miles. The road distance is 271.6 miles.
The best way to get from Chicago to Mendon without a car is to train which takes 4h 39m and costs $120 - $230.
It takes approximately 4h 39m to get from Chicago to Mendon, including transfers.
Chicago to Mendon train services, operated by Amtrak, depart from Chicago Union Station.
Chicago to Mendon train services, operated by Amtrak, arrive at Quincy Amtrak Station.
Yes, the driving distance between Chicago to Mendon is 272 miles. It takes approximately 5h 40m to drive from Chicago to Mendon.
There are 14+ hotels available in Mendon.
What companies run services between Chicago, IL, USA and Mendon, IL, USA?
Amtrak operates a train from Chicago Union Station to Quincy Amtrak Station twice daily. Tickets cost $80–180 and the journey takes 4h 22m.
- Website
- southwest.com
Flights from Chicago Midway International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- $70–500
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to Quincy Amtrak Station
- Ave. Duration
- 4h 22m
- Frequency
- Twice daily
- Estimated price
- $80–180
- Website
- Amtrak
- Phone
- +1-888-875-6287
- Website
- Oats Transit
Shuttle from St. Louis to Palmyra
- Ave. Duration
- 2h
- Frequency
- Twice a week
- Estimated price
- $4–7
- Website
- Oats Transit
- Schedules at
- Oats Transit Schedules
- Ave. Duration
- 42 min
- Estimated price
- $85–110
Diamond Cab
- Phone
- +1-217-222-6700
Quincy Premium Transportation
- Phone
- +1 217-901-7433
- Website
- quincypremiumtransportation.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide