There are 5 ways to get from Chicago to Mendon by train (Amtrak), car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from Chicago Union Station to Quincy Amtrak Stationtrain Carl Sandburg / ...
4h 39m$145–255Drive 270 mi
cheapest- Drive from Chicago to Mendoncar 270 mi
5h 40m$50–72Fly to Quincy Regional Airport
- Fly from Chicago O'Hare International Airport (ORD) to Quincy Regional Airport (UIN)plane ORD - UIN
3h 27m$112–205Fly to Burlington Municipal Airport, drive
- Fly from Chicago O'Hare International Airport (ORD) to Burlington Municipal Airport (BRL)plane ORD - BRL
- Drive from Burlington Municipal Airport (BRL) to Mendoncar
4h 35m$68–153Fly to Kirksville Regional Airport, drive
- Fly from Chicago O'Hare International Airport (ORD) to Kirksville Regional Airport (IRK)plane ORD - IRK
- Drive from Kirksville Regional Airport (IRK) to Mendoncar
5h 25m$82–218
Chicago O'Hare International Airport (ORD) to Quincy Regional Airport (UIN) flights
Questions & Answers
The cheapest way to get from Chicago to Mendon is to drive which costs $45 - $75 and takes 5h 40m.
The fastest way to get from Chicago to Mendon is to fly which takes 3h 27m and costs $110 - $210.
No, there is no direct train from Chicago station to Mendon station. However, there are services departing from Chicago Union Station and arriving at Quincy Amtrak Station via . The journey, including transfers, takes approximately 4h 39m.
The distance between Chicago and Mendon is 322 miles. The road distance is 271.6 miles.
The best way to get from Chicago to Mendon without a car is to train which takes 4h 39m and costs $140 - $260.
It takes approximately 4h 39m to get from Chicago to Mendon, including transfers.
Chicago to Mendon train services, operated by Amtrak, depart from Chicago Union Station.
The best way to get from Chicago to Mendon is to train which takes 4h 39m and costs $140 - $260. Alternatively, you can fly, which costs $110 - $210 and takes 3h 27m.
Chicago to Mendon train services, operated by Amtrak, arrive at Quincy Amtrak Station.
Yes, the driving distance between Chicago to Mendon is 272 miles. It takes approximately 5h 40m to drive from Chicago to Mendon.
What companies run services between Chicago, IL, USA and Mendon, IL, USA?
Amtrak operates a train from Chicago Union Station to Quincy Amtrak Station twice daily. Tickets cost $100–200 and the journey takes 4h 22m. Alternatively, Corporate Flight Management Inc flies from Chicago O'Hare International Airport (ORD) to Quincy Regional Airport (UIN) once daily.
- Website
- contouraviation.com
Flights from Chicago O'Hare International Airport to Quincy Regional Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- $55–130
Flights from Chicago O'Hare International Airport to Burlington Municipal Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- $55–130
Flights from Chicago O'Hare International Airport to Kirksville Regional Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $65–190
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Quincy Amtrak Station
- Ave. Duration
- 4h 22m
- Frequency
- Twice daily
- Estimated price
- $100–200
- Website
- https://www.amtrak.com/home.html
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More Questions & Answers
There are 14+ hotels available in Mendon.



