There are 10 ways to get from Chicago to Mercersburg by plane, car, train, taxi, bus (Greyhound, Amtrak), bus, or subway
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Chicago O'Hare International Airport to Johnstown-Cambria County Airport, drive
best- Fly from Chicago O'Hare International Airport (ORD) to Johnstown-Cambria County Airport (JST)plane ORD - JST
- Drive from Johnstown-Cambria County Airport (JST) to Mercersburgcar
5h 13m$66–337Train, taxi
- Take the train from Chicago Union Station to Martinsburg Amtrak Stationtrain Floridian
- Take the taxi from Martinsburg Amtrak Station to Mercersburgtaxi
16h 12m$259–491Bus
- Take the bus from Chicago Bus Station to Frederick Bus Stationbus Greyhound US0164
- Take the bus from Frederick Transit Center to Washington County Transfer Centerbus Bwi
17h 23m$197–327Drive 602.6 mi
- Drive from Chicago to Mercersburgcar 602.6 mi
10h 2m$110–159Fly Chicago Midway International Airport to Baltimore-Washington International Airport, bus
- Fly from Chicago Midway International Airport (MDW) to Baltimore-Washington International Airport (BWI)plane MDW - BWI
- Take the bus from Baltimore Airport to Washington Cty Transit Cnter - Hagerstownbus
6h 53m$252–465Subway to Chicago Midway International Airport, fly to Ronald Reagan Washington National Airport, subway, bus, taxi
- Take the subway from Adams/Wabash to Midwaysubway
- Fly from Chicago Midway International Airport (MDW) to Ronald Reagan Washington National Airport (DCA)plane MDW - DCA
- Take the subway from Gallery Place, Red Line Track 2 Platform to Shady Grove, Red Line Center Platformsubway
- Take the bus from SHADY GROVE & station to Hagerstown & Mva P&Rbus
- Take the taxi from Hagerstown & Mva P&R to Mercersburgtaxi
6h 47m$174–774Fly Chicago O'Hare International Airport to Harrisburg International Airport, bus, taxi
- Fly from Chicago O'Hare International Airport (ORD) to Harrisburg International Airport (MDT)plane ORD - MDT
- Take the bus from Market Square Transfer Center to Lancaster Dr & Cumberland Drbus
- Take the taxi from Lancaster Dr & Cumberland Dr to Mercersburgtaxi
7h 28m$130–422Fly Chicago O'Hare International Airport to Washington Dulles International Airport, subway, bus
- Fly from Chicago O'Hare International Airport (ORD) to Washington Dulles International Airport (IAD)plane ORD - IAD
- Take the subway from Washington Dulles International Airport, Silver Line Center Platform to Farragut West, Blue/Orange/Silver Line Track 1 Platformsubway
- Take the bus from SHADY GROVE & station to Hagerstown & Mva P&Rbus
7h 52m$234–973Fly Chicago O'Hare International Airport to Penn State University Park Airport, bus, taxi
- Fly from Chicago O'Hare International Airport (ORD) to Penn State University Park Airport (SCE)plane ORD - SCE
- Take the bus from State College, Pa to Big Runbus
- Take the taxi from Big Run to Mercersburgtaxi
9h 10m$150–500Bus, taxi
- Take the bus from Chicago Bus Station to State College Regional Airportbus
- Take the bus from State College, Pa to Big Runbus 600
- Take the taxi from Big Run to Mercersburgtaxi
19h 40m$195–329
Chicago O'Hare International Airport (ORD) to Johnstown-Cambria County Airport (JST) flights
Questions & Answers
The cheapest way to get from Chicago to Mercersburg is to drive which costs $110 - $160 and takes 10h 2m.
The fastest way to get from Chicago to Mercersburg is to fly and drive which takes 5h 13m and costs $65 - $340.
No, there is no direct bus from Chicago station to Mercersburg. However, there are services departing from Chicago Bus Station and arriving at Washington County Transfer Center via Frederick Transit Center. The journey, including transfers, takes approximately 17h 23m.
The distance between Chicago and Mercersburg is 587 miles. The road distance is 606.1 miles.
The best way to get from Chicago to Mercersburg without a car is to train and taxi which takes 16h 12m and costs $250 - $500.
It takes approximately 5h 13m to get from Chicago to Mercersburg, including transfers.
Chicago to Mercersburg bus services, operated by Greyhound USA, depart from Chicago Bus Station.
Chicago to Mercersburg bus services, operated by Greyhound USA, arrive at Frederick Bus Station.
Mercersburg is 1h ahead of Chicago. It is currently 4:23 AM in Chicago and 5:23 AM in Mercersburg.
Yes, the driving distance between Chicago to Mercersburg is 606 miles. It takes approximately 10h 2m to drive from Chicago to Mercersburg.
What companies run services between Chicago, IL, USA and Mercersburg, PA, USA?
You can take a bus from Chicago Bus Station to Mercersburg via Frederick Transit Center and Washington County Transfer Center in around 17h 23m.
- Website
- southwest.com
Flights from Chicago Midway International Airport to Baltimore-Washington International Airport
- Ave. Duration
- 1h 47m
- When
- Every day
- Estimated price
- $95–550
Flights from Chicago Midway International Airport to Baltimore-Washington International Airport via Indianapolis
- Ave. Duration
- 3h 32m
- When
- Sunday, Monday, Thursday, and Friday
- Estimated price
- $100–550
Flights from Chicago Midway International Airport to Baltimore-Washington International Airport via Columbus
- Ave. Duration
- 4h
- When
- Sunday
- Estimated price
- $95–550
Flights from Chicago Midway International Airport to Baltimore-Washington International Airport via Cleveland
- Ave. Duration
- 4h 20m
- When
- Sunday
- Estimated price
- $95–550
Flights from Chicago Midway International Airport to Ronald Reagan Washington National Airport
- Ave. Duration
- 1h 49m
- When
- Every day
- Estimated price
- $120–700
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to Martinsburg Amtrak Station
- Ave. Duration
- 15h 26m
- Frequency
- Once daily
- Estimated price
- $180–410
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Chicago Bus Station to Frederick Bus Station
- Ave. Duration
- 15h 20m
- Frequency
- Twice daily
- Estimated price
- $100–170
- Website
- Greyhound
- Ave. Duration
- 45 min
- Estimated price
- $45–90
Bonnie's Transportation
- Phone
- +1 240-527-5377
Yellow Cab Hagerstown
- Phone
- +1-301-547-3845
Bonnie's Transportation
- Phone
- +1 240-527-5377
Yellow Cab Hagerstown
- Phone
- +1-301-547-3845
Chambersburg City Cab
- Phone
- +1 717-561-1538
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More Questions & Answers
There are 18+ hotels available in Mercersburg.





