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How to get fromChicago to Mesaby plane, train, bus, bus (Greyhound), or car

Find Transport to Mesa

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There are 6 ways to get from Chicago to Mesa by plane, train, bus, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Chicago Midway International Airport

    best
    1. Fly from Chicago Midway International Airport (MDW) to Phoenix (PHX)plane plane MDW - PHX
    6h 7m
    $124–237
  2. Train, bus

    1. Take the train from Chicago Union Station to Flagstafftrain train Southwest Chief
    2. Take the bus from Flagstaff Train Station to Tempebus bus FlixBus 2047
    36h 5m
    $431–999
  3. Bus (Greyhound)

    1. Take the bus from Chicago Bus Station to Denver Union Stationbus bus
    2. Take the bus from Denver Union Station to El Paso Bus Stationbus bus
    3. Take the bus from El Paso Bus Station to Phoenix Sky Harbor Airport/44th Street Sky Train Stationbus bus
    47h 48m
    $333–532
  4. Drive  1,688.8 mi

    1. Drive from Chicago to Mesacar car 1,688.8 mi
    29h 38m
    $309–446
  5. Fly from Chicago O'Hare International Airport

    1. Fly from Chicago O'Hare International Airport (ORD) to Phoenix (PHX)plane plane ORD - PHX
    6h 29m
    $194–377
  6. Train to General Mitchell International Airport, fly

    1. Take the train from Chicago Union Station to Milwaukeetrain train
    2. Fly from General Mitchell International Airport (MKE) to Phoenix (PHX)plane plane MKE - PHX
    7h 40m
    $275–615

Chicago to Mesa by train, bus, and tram

Calendar5Weekly Services
Duration36h 5mAverage Duration
Ticket$431Cheapest Price
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Comparing Your Travel Options

What companies run services between Chicago, IL, USA and Mesa, AZ, USA?

Southwest Airlines flies from Chicago Midway International Airport (MDW) to Phoenix (PHX) every 3 hours. Alternatively, you can take a bus from Chicago Bus Station to University Dr & Mesa Dr via Denver Union Station, El Paso Bus Station, Phoenix Sky Harbor Airport/44th Street Sky Train Station, 44th St/Washington, University Dr/Rural Rd, and University Dr & Rural Rd in around 47h 48m.

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Need to know: Greyhound

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