There are 8 ways to get from Chicago to Mexicali by plane, bus, train, bus (Flixbus, Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Chicago O'Hare International Airport to San Diego International Airport, bus
best- Fly from Chicago O'Hare International Airport (ORD) to San Diego International Airport (SAN)plane ORD - SAN
- Take the bus from Tijuana to Mexicalibus
8h 57m$2,395–10,100Fly Chicago O'Hare International Airport to Yuma International Airport, bus
cheapest- Fly from Chicago O'Hare International Airport (ORD) to Yuma International Airport (YUM)plane ORD - YUM
- Take the bus from San Luis Río Colorado to Mexicalibus
11h 19m$2,176–10,120Train, bus via Flagstaff
- Take the train from Chicago Union Station to Flagstafftrain
- Take the bus from Flagstaff Train Station to Phoenix Sky Harbor Airport/44th Street Sky Train Stationbus
- Take the bus from Phoenix Sky Harbor Airport/44th Street Sky Train Station to Calexico Bus Stationbus
41h 43m$8,498–19,188Bus
- Take the bus from Chicago Bus Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Phoenix Bus Stationbus
- Take the bus from Phoenix Bus Station to Calexico Bus Stationbus
43h 19m$5,760–9,375Drive 3,111.4 km
- Drive from Chicago to Mexicalicar 3,111.4 km
34h 6m$6,345–9,164Fly Chicago Midway International Airport to San Diego International Airport, bus
- Fly from Chicago Midway International Airport (MDW) to San Diego International Airport (SAN)plane MDW - SAN
- Take the bus from Tijuana to Mexicalibus
10h 27m$3,195–14,100Fly Chicago Midway International Airport to Imperial County Airport
- Fly from Chicago Midway International Airport (MDW) to Imperial County Airport (IPL)plane MDW - IPL
8h 56m$4,210–19,190Train, bus
- Take the train from Chicago Union Station to Yuma Amtraktrain
- Take the bus from 3rd Street @ Gila Street to William Brook Ave @ B Streetbus 95
- Take the bus from San Luis Río Colorado to Mexicalibus
2d 15h$11,036–26,776
Chicago to Mexicali by train, bus, and foot
Comparing Your Travel Options
The cheapest way to get from Chicago to Mexicali is to fly and bus which costs $2100 - $11000 and takes 11h 19m.
The fastest way to get from Chicago to Mexicali is to fly which takes 8h 56m and costs $4200 - $20000.
No, there is no direct bus from Chicago station to Mexicali. However, there are services departing from Chicago Bus Station and arriving at Central de Autobuses de Mexicali via St Louis Bus Station, Phoenix Bus Station and C. José Azueta y Blvr. López Mateos. The journey, including transfers, takes approximately 43h 19m.
The distance between Chicago and Mexicali is 3008 km. The road distance is 3111.4 km.
The best way to get from Chicago to Mexicali without a car is to train and bus via Flagstaff which takes 41h 43m and costs $8500 - $20000.
It takes approximately 8h 57m to get from Chicago to Mexicali, including transfers.
Chicago to Mexicali bus services, operated by Flixbus USA, depart from Chicago Bus Station.
The best way to get from Chicago to Mexicali is to bus which takes 43h 19m and costs $5500 - $9500. Alternatively, you can fly, which costs $4200 - $20000 and takes 8h 56m.
Chicago to Mexicali bus services, operated by Flixbus USA, arrive at St Louis Bus Station.
Mexicali is 2h behind Chicago. It is currently 3:42 AM in Chicago and 1:42 AM in Mexicali.
What companies run services between Chicago, IL, USA and Mexicali, Mexico?
You can take a bus from Chicago Bus Station to Central de Autobuses de Mexicali via St Louis Bus Station, Phoenix Bus Station, Calexico Bus Station, and C. José Azueta y Blvr. López Mateos in around 43h 19m. Alternatively, Southwest Airlines and Southern Airways Express fly from Chicago Midway International Airport (MDW) to Imperial County Airport (IPL) twice daily.
- Website
- southwest.com
Flights from Chicago Midway International Airport to San Diego International Airport
- Ave. Duration
- 4h 17m
- When
- Every day
- Estimated price
- $2,700–13,000
Flights from Chicago Midway International Airport to San Diego International Airport via Phoenix
- Ave. Duration
- 6h 12m
- When
- Every day
- Estimated price
- $2,800–13,000
Flights from Chicago Midway International Airport to San Diego International Airport via El Paso
- Ave. Duration
- 6h
- When
- Sunday
- Estimated price
- $2,900–13,000
Flights from Chicago Midway International Airport to San Diego International Airport via Omaha
- Ave. Duration
- 6h 22m
- When
- Saturday and Sunday
- Estimated price
- $2,700–13,000
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to Flagstaff
- Ave. Duration
- 31h 44m
- Frequency
- Once daily
- Estimated price
- $7,000–18,000
- Website
- Amtrak
Train from Chicago Union Station to Yuma Amtrak
- Ave. Duration
- 2d 11h
- Frequency
- 3 times a week
- Estimated price
- $10,000–26,000
- Website
- Amtrak
- Phone
- +52 664 104 7400
- [email protected]
- Website
- abc.com.mx
Bus from Tijuana to Mexicali
- Ave. Duration
- 2h 5m
- Frequency
- Every 3 hours
- Estimated price
- $360–650
- Schedules at
- abc.com.mx
- Book at
- abc.com.mx
Bus from San Luis Río Colorado to Mexicali
- Ave. Duration
- 1h 30m
- Frequency
- 5 times a day
- Estimated price
- $140–330
- Schedules at
- abc.com.mx
- Book at
- abc.com.mx
Bus from Tijuana to Mexicali
- Ave. Duration
- 2h 5m
- Frequency
- Every 3 hours
- Estimated price
- $360–650
- Schedules at
- abc.com.mx
- Book at
- abc.com.mx
Bus from San Luis Río Colorado to Mexicali
- Ave. Duration
- 1h 30m
- Frequency
- 5 times a day
- Estimated price
- $140–330
- Schedules at
- abc.com.mx
- Book at
- abc.com.mx
Want to know more about travelling around Mexico
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Yes, the driving distance between Chicago to Mexicali is 3111 km. It takes approximately 34h 6m to drive from Chicago to Mexicali.
There are 96+ hotels available in Mexicali.










