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How to get fromChicago to Missionby plane, bus (Greyhound), train, bus, or car

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There are 6 ways to get from Chicago to Mission by plane, bus (Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Mcallen Miller International Airport

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Mcallen Miller International Airport (MFE)plane plane ORD - MFE
    6h 55m
    $172–730

  2. Fly Chicago Midway International Airport to Rio Grande Valley International Airport, bus

    cheapest
    1. Fly from Chicago Midway International Airport (MDW) to Rio Grande Valley International Airport (HRL)plane plane MDW - HRL
    2. Take the bus from Harlingen Bus Station to Palmviewbus bus
    9h 49m
    $150–670

  3. Bus

    1. Take the bus from Chicago to Laredobus bus Chicago
    2. Take the bus from Laredo Bus Station to Palmviewbus bus Greyhound US1169s
    31h 41m
    $226–423

  4. Train, bus via Dallas

    1. Take the train from Chicago Union Station to Dallastrain train Texas Eagle
    2. Take the bus from Dallas to McAllen Central Stationbus bus Dallas
    33h 7m
    $417–770

  5. Drive 1,429 mi

    1. Drive from Chicago to Missioncar car 1,429 mi
    23h 45m
    $261–377

  6. Train, bus

    1. Take the train from Chicago Union Station to San Marcos Amtraktrain train Texas Eagle
    2. Take the bus from San Marcos to McAllen Central Stationbus bus FlixBus US1164
    40h 49m
    $466–915

Chicago to Mission by subway, bus, and foot

Calendar7Weekly Services
Duration31h 41mAverage Duration
Ticket$226Cheapest Price
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Questions & Answers

Map of how to get from Chicago to Mission.ExpandLaunch map view
  • Distance: 1,264.3 mi
  • Duration: 6h 55m

What companies run services between Chicago, IL, USA and Mission, TX, USA?

American Airlines and United Airlines fly from Chicago O'Hare International Airport (ORD) to Mcallen Miller International Airport (MFE) every 3 hours. Alternatively, you can take a subway from Harold Washington Library to Palmview via 35th/Archer, 35th/Archer Orange Line Station, California & 35th Street, Chicago, Laredo, and Laredo Bus Station in around 31h 41m.

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