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How to get fromChicago to Mississippiby plane, bus (Greyhound, Flixbus), train (Amtrak), or car

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There are 5 ways to get from Chicago to Mississippi by plane, bus (Greyhound, Flixbus), train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Chicago O'Hare International Airport

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Memphis (MEM)plane plane ORD - MEM
    3h 46m
    $120–632
  2. Bus

    cheapest
    1. Take the bus from Chicago Bus Station to Memphis Bus Stationbus bus Greyhound US0125
    2. Take the bus from Memphis Bus Station to Jacksonbus bus Greyhound US1173
    14h 15m
    $113–221
  3. Train (Amtrak)

    1. Take the train from Chicago Union Station to Jacksontrain train City of New Orleans
    15h 35m
    $240–490
  4. Drive 739.2 mi

    1. Drive from Chicago to Jacksoncar car 739.2 mi
    11h 59m
    $135–195
  5. Fly from Chicago Midway International Airport

    1. Fly from Chicago Midway International Airport (MDW) to Memphis (MEM)plane plane MDW - MEM
    3h 20m
    $144–782

Chicago to Mississippi by bus

Calendar7Weekly Buses
Duration14h 15mAverage Duration
Ticket$113Cheapest Price
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Questions & Answers

What companies run services between Chicago, IL, USA and Mississippi, USA?

American Airlines, United Airlines, and Delta fly from Chicago O'Hare International Airport (ORD) to Memphis (MEM) every 2 hours. Alternatively, you can take a bus from Chicago Bus Station to Jackson via Memphis Bus Station in around 14h 15m.

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