There are 9 ways to get from Chicago to Missouri by plane, train (Amtrak), bus (Greyhound), car, or subway
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Chicago O'Hare International Airport to Lambert–St. Louis International Airport
best- Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane ORD - STL
3h 43m$316–708Fly Chicago O'Hare International Airport to Springfield-Branson National Airport
cheapest- Fly from Chicago O'Hare International Airport (ORD) to Springfield-Branson National Airport (SGF)plane ORD - SGF
3h 40m$68–345Train (Amtrak)
- Take the train from Chicago Union Station to Kansas Citytrain Southwest Chief / ...
7h 35m$130–280Bus (Greyhound)
- Take the bus from Chicago Bus Station to Des Moinesbus Greyhound US0123S / ...
- Take the bus from Des Moines to Kansas City Bus Stationbus Greyhound US0156
10h 45m$78–149Drive 506.6 mi
- Drive from Chicago to Kansas Citycar 506.6 mi
8h 37m$93–134Subway to Chicago Midway International Airport, fly to Lambert–St. Louis International Airport
- Take the subway from Adams/Wabash to Midwaysubway
- Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane MDW - STL
3h 27m$76–508Fly Chicago O'Hare International Airport to Columbia Regional Airport
- Fly from Chicago O'Hare International Airport (ORD) to Columbia Regional Airport (COU)plane ORD - COU
3h 30m$98–370Subway to Chicago Midway International Airport, fly to Kansas City
- Take the subway from Adams/Wabash to Midwaysubway
- Fly from Chicago Midway International Airport (MDW) to Kansas City (MCI)plane MDW - MCI
4h 39m$102–655Fly Chicago O'Hare International Airport to Kansas City
- Fly from Chicago O'Hare International Airport (ORD) to Kansas City (MCI)plane ORD - MCI
5h 1m$352–805
Chicago to Missouri by train and tram (Amtrak)
Questions & Answers
The cheapest way to get from Chicago to Missouri is to bus which costs $75 - $150 and takes 10h 45m.
The fastest way to get from Chicago to Missouri is to subway and fly which takes 3h 27m and costs $75 - $550.
No, there is no direct bus from Chicago station to Missouri station. However, there are services departing from Chicago Bus Station and arriving at Kansas City Bus Station via Des Moines. The journey, including transfers, takes approximately 10h 45m.
No, there is no direct train from Chicago station to Missouri. However, there are services departing from Chicago Union Station and arriving at Metro Center via Union Station. The journey, including transfers, takes approximately 7h 35m.
The distance between Chicago and Missouri is 292 miles. The road distance is 509.6 miles.
The best way to get from Chicago to Missouri without a car is to train which takes 7h 35m and costs $130 - $280.
It takes approximately 3h 43m to get from Chicago to Missouri, including transfers.
Chicago to Missouri bus services, operated by Greyhound USA, depart from Chicago Bus Station.
Chicago to Missouri train services, operated by Amtrak, depart from Chicago Union Station.
The best way to get from Chicago to Missouri is to fly which takes 3h 43m and costs $310 - $750. Alternatively, you can train, which costs $130 - $280 and takes 7h 35m, you could also bus, which costs $75 - $150 and takes 10h 45m.
What companies run services between Chicago, IL, USA and Missouri, USA?
American Airlines, GoJet Airlines, and United Airlines fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL) hourly. Alternatively, Amtrak operates a train from Chicago Union Station to Kansas City twice daily. Tickets cost $130–280 and the journey takes 7h 23m.
- Website
- southwest.com
Flights from Chicago Midway International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- $70–500
Flights from Chicago Midway International Airport to Kansas City
- Ave. Duration
- 1h 26m
- When
- Every day
- Estimated price
- $100–650
Flights from Chicago Midway International Airport to Kansas City via Indianapolis
- Ave. Duration
- 3h 45m
- When
- Sunday
- Estimated price
- $120–700
- Website
- united.com
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $60–410
Flights from Chicago O'Hare International Airport to Columbia Regional Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- $45–300
Flights from Chicago O'Hare International Airport to Springfield-Branson National Airport
- Ave. Duration
- 1h 52m
- When
- Every day
- Estimated price
- $50–320
Flights from Chicago O'Hare International Airport to Kansas City
- Ave. Duration
- 1h 44m
- When
- Every day
- Estimated price
- $80–490
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- $60–410
Flights from Chicago O'Hare International Airport to Columbia Regional Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $45–300
Flights from Chicago O'Hare International Airport to Springfield-Branson National Airport
- Ave. Duration
- 1h 44m
- When
- Every day
- Estimated price
- $50–320
Flights from Chicago O'Hare International Airport to Kansas City
- Ave. Duration
- 1h 43m
- When
- Every day
- Estimated price
- $80–490
- Website
- gojetairlines.com
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $60–410
- Website
- delta.com
Flights from Chicago O'Hare International Airport to Kansas City via Minneapolis
- Ave. Duration
- 4h 2m
- When
- Every day
- Estimated price
- $110–600
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to Kansas City
- Ave. Duration
- 7h 23m
- Frequency
- Twice daily
- Estimated price
- $130–280
- Website
- Amtrak
- Phone
- +1 888-968-7282
- Website
- Chicago Transit Authority
Subway from Adams/Wabash to Midway
- Ave. Duration
- 23 min
- Frequency
- Every 15 minutes
- Estimated price
- $2–5
- Website
- Chicago Transit Authority
- Schedules at
- Chicago Transit Authority Schedules & Routes
- Adult
- $2–5
Subway from Adams/Wabash to Midway
- Ave. Duration
- 23 min
- Frequency
- Every 15 minutes
- Estimated price
- $2–5
- Website
- Chicago Transit Authority
- Schedules at
- Chicago Transit Authority Schedules & Routes
- Adult
- $2–5
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 6h 30m
- Frequency
- 3 times a day
- Estimated price
- $45–95
- Website
- Greyhound
Bus from Des Moines to Kansas City Bus Station
- Ave. Duration
- 3h 15m
- Frequency
- Once daily
- Estimated price
- $28–55
- Website
- Greyhound
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More Questions & Answers
Chicago to Missouri bus services, operated by Greyhound USA, arrive at Des Moines station.
Chicago to Missouri train services, operated by Amtrak, arrive at Kansas City station.
Yes, the driving distance between Chicago to Missouri is 510 miles. It takes approximately 8h 37m to drive from Chicago to Missouri.
Book your Chicago to Missouri bus tickets online with FlixBus.
There are 340+ hotels available in Missouri.