There are 6 ways to get from Chicago to Missouri Botanical Garden by train (Amtrak), bus (Flixbus), car, subway, plane, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from Chicago Union Station to St. Louistrain Lincoln Service / ...
5h 38m$158–241Bus (Flixbus)
cheapest- Take the bus from Chicago Bus Station to St Louis Bus Stationbus FlixBus 2510 / ...
7h 15m$52–76Drive 299.7 mi
- Drive from Chicago to Missouri Botanical Gardencar 299.7 mi
5h 3m$52–74Subway to Chicago Midway International Airport, fly, line 8 bus
- Take the subway from Adams/Wabash to Midwaysubway
- Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane MDW - STL
- Take the bus from Central West End Transit Center to Shaw @ Tower Grove Ebbus
4h 6m$92–609Fly from Chicago O'Hare International Airport, line 8 bus
- Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane ORD - STL
- Take the bus from Central West End Transit Center to Shaw @ Tower Grove Ebbus
4h 25m$326–709Train to General Mitchell International Airport, fly
- Take the train from Chicago Union Station to Milwaukeetrain
- Fly from General Mitchell International Airport (MKE) to Lambert–St. Louis International Airport (STL)plane MKE - STL
5h 45m$143–689
Chicago to Missouri Botanical Garden by bus and foot (Flixbus)
Comparing Your Travel Options
The cheapest way to get from Chicago to Missouri Botanical Garden is to bus which costs $50 - $80 and takes 7h 15m.
The fastest way to get from Chicago to Missouri Botanical Garden is to subway and fly and line 8 bus which takes 4h 6m and costs $90 - $650.
No, there is no direct bus from Chicago station to Missouri Botanical Garden. However, there are services departing from Chicago Bus Station and arriving at Arsenal @ Bent Wb via Civic Center Transit Center. The journey, including transfers, takes approximately 7h 15m.
No, there is no direct train from Chicago station to Missouri Botanical Garden station. However, there are services departing from Chicago Union Station and arriving at GRAND station via CIVIC CENTER station. The journey, including transfers, takes approximately 5h 38m.
The distance between Chicago and Missouri Botanical Garden is 288 miles. The road distance is 301.5 miles.
The best way to get from Chicago to Missouri Botanical Garden without a car is to train which takes 5h 38m and costs $150 - $250.
It takes approximately 5h 38m to get from Chicago to Missouri Botanical Garden, including transfers.
Chicago to Missouri Botanical Garden bus services, operated by Flixbus USA, depart from Chicago Bus Station.
Chicago to Missouri Botanical Garden train services, operated by Amtrak, depart from Chicago Union Station.
The best way to get from Chicago to Missouri Botanical Garden is to train which takes 5h 38m and costs $150 - $250. Alternatively, you can bus, which costs $50 - $80 and takes 7h 15m.
What companies run services between Chicago, IL, USA and Missouri Botanical Garden, MO, USA?
Amtrak operates a train from Chicago Union Station to St. Louis 5 times a day. Tickets cost $150–240 and the journey takes 4h 46m. Alternatively, Flixbus USA operates a bus from Chicago Bus Station to St Louis Bus Station twice daily. Tickets cost $50–75 and the journey takes 5h 55m.
- Website
- southwest.com
Flights from Chicago Midway International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 16m
- When
- Every day
- Estimated price
- $85–600
Flights from General Mitchell International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $90–600
Flights from General Mitchell International Airport to Lambert–St. Louis International Airport via Chicago Midway International Airport
- Ave. Duration
- 3h 12m
- When
- Monday, Thursday, Friday, Sunday, and Saturday
- Estimated price
- $95–600
- Website
- united.com
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $50–350
Flights from General Mitchell International Airport to Lambert–St. Louis International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 3h 37m
- When
- Monday to Saturday
- Estimated price
- $90–600
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- $50–350
- Website
- gojetairlines.com
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 38m
- When
- Every day
- Estimated price
- $50–350
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to St. Louis
- Ave. Duration
- 4h 46m
- Frequency
- 5 times a day
- Estimated price
- $150–240
- Website
- Amtrak
Train from Chicago Union Station to Milwaukee
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $45–75
- Website
- Amtrak
- Phone
- +1 888-968-7282
- Website
- Chicago Transit Authority
Subway from Adams/Wabash to Midway
- Ave. Duration
- 23 min
- Frequency
- Every 15 minutes
- Estimated price
- $2–5
- Website
- Chicago Transit Authority
- Schedules at
- Chicago Transit Authority Schedules & Routes
- Adult
- $2–5
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Chicago Bus Station to St Louis Bus Station
- Ave. Duration
- 5h 55m
- Frequency
- Twice daily
- Estimated price
- $50–75
- Schedules at
- Flixbus USA
- Phone
- 314-982-1406
- [email protected]
- Website
- Metro St Louis
Bus from Central West End Transit Center to Shaw @ Tower Grove Eb
- Ave. Duration
- 11 min
- Frequency
- Hourly
- Estimated price
- $1
- Website
- Metro St Louis
Bus from Central West End Transit Center to Shaw @ Tower Grove Eb
- Ave. Duration
- 11 min
- Frequency
- Hourly
- Estimated price
- $1
- Website
- Metro St Louis
Want to know more about travelling around United States
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Booking & Getting There
Chicago to Missouri Botanical Garden bus services, operated by Flixbus USA, arrive at St Louis Bus Station.
Chicago to Missouri Botanical Garden train services, operated by Amtrak, arrive at St. Louis station.
Yes, the driving distance between Chicago to Missouri Botanical Garden is 301 miles. It takes approximately 5h 3m to drive from Chicago to Missouri Botanical Garden.
There are 568+ hotels available in Missouri Botanical Garden.














