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How to get fromChicago to Mount Pleasantby subway, plane, bus, car, train (Amtrak), or train

Find Transport to Mount Pleasant

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There are 7 ways to get from Chicago to Mount Pleasant by subway, plane, bus, car, train (Amtrak), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Subway to Chicago Midway International Airport, fly to Charleston International Airport, line 41 bus

    best
    1. Take the subway from Adams/Wabash to Midwaysubway subway
    2. Fly from Chicago Midway International Airport (MDW) to Charleston International Airport (CHS)plane plane MDW - CHS
    3. Take the bus from Mary St / Meeting St to Coleman Blvd / Chuck Dawley Blvdbus bus
    6h 37m
    $106–559

  2. Fly Chicago O'Hare International Airport to Charleston International Airport, line 41 bus

    cheapest
    1. Fly from Chicago O'Hare International Airport (ORD) to Charleston International Airport (CHS)plane plane ORD - CHS
    2. Take the bus from Mary St / Meeting St to Coleman Blvd / Chuck Dawley Blvdbus bus
    7h 4m
    $92–429

  3. Bus, drive

    1. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus bus
    3. Drive from Myrtle Beach Bus Station to S. Pinckney St / Society Rdcar car
    4. Take the bus from S. Pinckney St / Society Rd to East Cooper Medical Centerbus bus
    28h 10m
    $186–356

  4. Train (Amtrak)

    1. Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain train Floridian
    2. Take the train from Petersburg Amtrak Station to Charleston Amtrak Stationtrain train Silver Meteor / ...
    28h 43m
    $446–883

  5. Drive 875.2 mi

    1. Drive from Chicago to Mount Pleasantcar car 875.2 mi
    16h 3m
    $160–231

  6. Fly Chicago O'Hare International Airport to Hilton Head Airport, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Hilton Head Airport (HHH)plane plane ORD - HHH
    2. Drive from Hilton Head Airport (HHH) to Mount Pleasantcar car
    6h 31m
    $102–424

  7. Train, bus, drive

    1. Take the train from Chicago Union Station to Raleigh Union Stationtrain train
    2. Take the bus from Raleigh Bus Station to Myrtle Beach Bus Stationbus bus
    3. Drive from Myrtle Beach Bus Station to S. Pinckney St / Society Rdcar car
    4. Take the bus from S. Pinckney St / Society Rd to Stuart Engals Blvd / Wando Crossing Centerbus bus
    39h 13m
    $442–873

Chicago Midway International Airport (MDW) to Charleston International Airport (CHS) flights

Calendar32Weekly Planes
Duration3h 35mAverage Duration
Ticket$107Cheapest Price
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Questions & Answers

Map of how to get from Chicago to Mount Pleasant.ExpandLaunch map view
  • Distance: 779.1 mi
  • Duration: 6h 37m

What companies run services between Chicago, IL, USA and Mount Pleasant, SC, USA?

You can take a train from Chicago Union Station to Mount Pleasant via Petersburg Amtrak Station and Charleston Amtrak Station in around 28h 43m.

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