There are 10 ways to get from Chicago to Natick by plane, train, train (Amtrak), bus (Flixbus), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Chicago O'Hare International Airport to Boston Logan Airport, train
best- Fly from Chicago O'Hare International Airport (ORD) to Boston Logan Airport (BOS)plane ORD - BOS
- Take the train from Back Bay to Natick Centertrain
6h 3m$614–1,023Fly Chicago O'Hare International Airport to Theodore Francis Green State Airport, train
cheapest- Fly from Chicago O'Hare International Airport (ORD) to Theodore Francis Green State Airport (PVD)plane ORD - PVD
- Take the train from TF Green Airport to Back Baytrain
8h 11m$70–330Train (Amtrak)
- Take the train from Chicago Union Station to Framingham Amtraktrain Lake Shore Limited
22h 26m$303–641Bus (Flixbus)
- Take the bus from Chicago Bus Station to New York Midtownbus FlixBus N2641 / ...
- Take the bus from New York Midtown to Bostonbus FlixBus 2610 / ...
23h 51m$165–277Drive 964.9 mi
- Drive from Chicago to Natickcar 964.9 mi
16h 33m$177–255Fly Chicago Midway International Airport to Boston Logan Airport
- Fly from Chicago Midway International Airport (MDW) to Boston Logan Airport (BOS)plane MDW - BOS
5h 46m$110–503Fly Chicago Midway International Airport to Manchester Airport, bus
- Fly from Chicago Midway International Airport (MDW) to Manchester Airport (MHT)plane MDW - MHT
- Take the bus from Boston Manchester Airport to Bostonbus
7h 42m$112–579Fly Chicago Midway International Airport to Theodore Francis Green State Airport, train
- Fly from Chicago Midway International Airport (MDW) to Theodore Francis Green State Airport (PVD)plane MDW - PVD
- Take the train from TF Green Airport to Back Baytrain
7h 41m$84–390Fly Chicago O'Hare International Airport to Manchester Airport, bus
- Fly from Chicago O'Hare International Airport (ORD) to Manchester Airport (MHT)plane ORD - MHT
- Take the bus from Boston Manchester Airport to Bostonbus
8h 15m$98–459Fly Chicago Midway International Airport to Bradley International Airport, bus, train
- Fly from Chicago Midway International Airport (MDW) to Bradley International Airport (BDL)plane MDW - BDL
- Take the bus from Hartford to Worcesterbus
- Take the train from Worcester to Natick Centertrain
8h 19m$116–555
Chicago to Natick by train (Amtrak)
Questions & Answers
The cheapest way to get from Chicago to Natick is to fly and train which costs $65 - $330 and takes 8h 11m.
The fastest way to get from Chicago to Natick is to fly which takes 5h 46m and costs $110 - $550.
No, there is no direct bus from Chicago station to Natick. However, there are services departing from Chicago Bus Station and arriving at Boston via New York Midtown. The journey, including transfers, takes approximately 23h 51m.
No, there is no direct train from Chicago station to Natick. However, there are services departing from Chicago Union Station and arriving at Natick Center via Framingham. The journey, including transfers, takes approximately 22h 26m.
The distance between Chicago and Natick is 914 miles. The road distance is 970.5 miles.
The best way to get from Chicago to Natick without a car is to train which takes 22h 26m and costs $300 - $650.
It takes approximately 6h 3m to get from Chicago to Natick, including transfers.
Chicago to Natick bus services, operated by Flixbus USA, depart from Chicago Bus Station.
Chicago to Natick train services, operated by Amtrak, depart from Chicago Union Station.
The best way to get from Chicago to Natick is to train which takes 22h 26m and costs $300 - $650. Alternatively, you can bus, which costs $160 - $280 and takes 23h 51m, you could also fly, which costs $110 - $550 and takes 5h 46m.
What companies run services between Chicago, IL, USA and Natick, MA, USA?
Amtrak operates a train from Chicago Union Station to Framingham Amtrak once daily. Tickets cost $300–650 and the journey takes 21h 28m. Alternatively, you can take a bus from Chicago Bus Station to Natick Center via New York Midtown, Boston, and South Station in around 23h 51m.
- Website
- southwest.com
Flights from Chicago Midway International Airport to Boston Logan Airport
- Ave. Duration
- 2h 20m
- When
- Every day
- Estimated price
- $95–480
Flights from Chicago Midway International Airport to Manchester Airport
- Ave. Duration
- 2h 12m
- When
- Every day
- Estimated price
- $100–550
Flights from Chicago Midway International Airport to Manchester Airport via Baltimore
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- $110–600
Flights from Chicago Midway International Airport to Manchester Airport via Nashville
- Ave. Duration
- 4h 55m
- When
- Monday, Thursday, and Friday
- Estimated price
- $140–650
Flights from Chicago Midway International Airport to Theodore Francis Green State Airport
- Ave. Duration
- 2h 18m
- When
- Every day
- Estimated price
- $70–360
Flights from Chicago Midway International Airport to Theodore Francis Green State Airport via Baltimore
- Ave. Duration
- 4h 29m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $75–380
Flights from Chicago Midway International Airport to Theodore Francis Green State Airport via Reagan Washington
- Ave. Duration
- 4h 51m
- When
- Monday, Thursday, Friday, Tuesday, Wednesday, and Sunday
- Estimated price
- $75–380
Flights from Chicago Midway International Airport to Bradley International Airport
- Ave. Duration
- 2h 7m
- When
- Every day
- Estimated price
- $95–500
Flights from Chicago Midway International Airport to Bradley International Airport via Baltimore
- Ave. Duration
- 4h 29m
- When
- Every day
- Estimated price
- $100–550
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Boston Logan Airport
- Ave. Duration
- 2h 36m
- When
- Every day
- Estimated price
- $75–400
Flights from Chicago O'Hare International Airport to Manchester Airport
- Ave. Duration
- 2h 28m
- When
- Every day
- Estimated price
- $85–430
Flights from Chicago O'Hare International Airport to Manchester Airport via Reagan Washington
- Ave. Duration
- 5h 18m
- When
- Every day
- Estimated price
- $95–470
Flights from Chicago O'Hare International Airport to Manchester Airport via Philadelphia
- Ave. Duration
- 5h 18m
- When
- Every day
- Estimated price
- $90–460
Flights from Chicago O'Hare International Airport to Theodore Francis Green State Airport
- Ave. Duration
- 2h 31m
- When
- Every day
- Estimated price
- $55–300
Flights from Chicago O'Hare International Airport to Theodore Francis Green State Airport via Philadelphia
- Ave. Duration
- 4h 47m
- When
- Saturday and Sunday
- Estimated price
- $60–310
Flights from Chicago O'Hare International Airport to Theodore Francis Green State Airport via Reagan Washington
- Ave. Duration
- 5h 10m
- When
- Every day
- Estimated price
- $60–310
- Website
- united.com
Flights from Chicago O'Hare International Airport to Boston Logan Airport
- Ave. Duration
- 2h 36m
- When
- Every day
- Estimated price
- $75–400
Flights from Chicago O'Hare International Airport to Manchester Airport via Washington Dulles
- Ave. Duration
- 4h 54m
- When
- Every day
- Estimated price
- $95–460
Flights from Chicago O'Hare International Airport to Theodore Francis Green State Airport
- Ave. Duration
- 2h 39m
- When
- Every day
- Estimated price
- $55–300
Flights from Chicago O'Hare International Airport to Theodore Francis Green State Airport via Washington Dulles
- Ave. Duration
- 4h 49m
- When
- Monday, Wednesday, Thursday, Friday, Sunday, and Tuesday
- Estimated price
- $60–310
- Website
- delta.com
Flights from Chicago O'Hare International Airport to Boston Logan Airport
- Ave. Duration
- 2h 35m
- When
- Every day
- Estimated price
- $75–400
Flights from Chicago Midway International Airport to Boston Logan Airport via Detroit
- Ave. Duration
- 4h 17m
- When
- Every day
- Estimated price
- $95–480
Flights from Chicago O'Hare International Airport to Theodore Francis Green State Airport via Detroit
- Ave. Duration
- 4h 12m
- When
- Every day
- Estimated price
- $55–300
Flights from Chicago Midway International Airport to Bradley International Airport via Detroit
- Ave. Duration
- 4h 9m
- When
- Every day
- Estimated price
- $95–500
- Website
- jetblue.com
Flights from Chicago O'Hare International Airport to Boston Logan Airport
- Ave. Duration
- 2h 29m
- When
- Every day
- Estimated price
- $75–400
Train from Back Bay to Natick Center
- Ave. Duration
- 36 min
- Frequency
- Hourly
- Estimated price
- $3–9
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $3–9
Train from TF Green Airport to Back Bay
- Ave. Duration
- 1h 23m
- Frequency
- Every 4 hours
- Estimated price
- $9–16
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $9–16
Train from TF Green Airport to Back Bay
- Ave. Duration
- 1h 23m
- Frequency
- Every 4 hours
- Estimated price
- $9–16
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $9–16
Train from Worcester to Natick Center
- Ave. Duration
- 51 min
- Frequency
- Every 2 hours
- Estimated price
- $5–11
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $5–11
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to Framingham Amtrak
- Ave. Duration
- 21h 28m
- Frequency
- Once daily
- Estimated price
- $300–650
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Chicago Bus Station to New York Midtown
- Ave. Duration
- 17h 5m
- Frequency
- Twice daily
- Estimated price
- $130–220
- Schedules at
- Flixbus USA
Bus from New York Midtown to Boston
- Ave. Duration
- 4h 20m
- Frequency
- Hourly
- Estimated price
- $30–55
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Boston Manchester Airport to Boston
- Ave. Duration
- 1h 30m
- Frequency
- Twice daily
- Estimated price
- $7–15
- Website
- Greyhound
Bus from Boston Manchester Airport to Boston
- Ave. Duration
- 1h 30m
- Frequency
- Twice daily
- Estimated price
- $7–15
- Website
- Greyhound
- Phone
- 1-800-343-9999
- Website
- Peter Pan
Bus from Hartford to Worcester
- Ave. Duration
- 1h
- Frequency
- 3 times a day
- Estimated price
- $13–35
- Website
- Peter Pan
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More Questions & Answers
Chicago to Natick bus services, operated by Flixbus USA, arrive at New York Midtown station.
Natick is 1h ahead of Chicago. It is currently 8:32 PM in Chicago and 9:32 PM in Natick.
Chicago to Natick train services, operated by Amtrak, arrive at Framingham Amtrak station.
Yes, the driving distance between Chicago to Natick is 970 miles. It takes approximately 16h 33m to drive from Chicago to Natick.
There are 385+ hotels available in Natick.















