Rome2Rio

How to get fromChicago to New Madridby plane, taxi, bus, train, car ferry, or car

Find Transport to New Madrid

See all options

There are 7 ways to get from Chicago to New Madrid by plane, taxi, bus, train, car ferry, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Cape Girardeau Municipal Airport, taxi

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Cape Girardeau Municipal Airport (CGI)plane plane ORD - CGI
    2. Take the taxi from Cape Girardeau Municipal Airport (CGI) to New Madridtaxi taxi
    4h 10m
    $232–575

  2. Fly to Barkley Regional Airport, drive

    cheapest
    1. Fly from Chicago O'Hare International Airport (ORD) to Barkley Regional Airport (PAH)plane plane ORD - PAH
    2. Drive from Barkley Regional Airport (PAH) to New Madridcar car
    4h 42m
    $56–305

  3. Bus

    1. Take the bus from Tornado Bus Co - Chicago to Flying J - Matthewsbus bus Milwaukee
    8h 58m
    $120–153

  4. Train, car ferry

    1. Take the train from Chicago Union Station to Fulton Amtrak Stationtrain train City of New Orleans
    2. Take the carferry from Hickman, KY to Dorena, MOcarferry car ferry Dorena-Hickman Ferry
    9h 43m
    $235–376

  5. Drive  412.6 mi

    1. Drive from Chicago to New Madridcar car 412.6 mi
    6h 47m
    $76–109

  6. Fly to Mc Kellar-Sipes Regional Airport, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Mc Kellar-Sipes Regional Airport (MKL)plane plane ORD - MKL
    2. Drive from Mc Kellar-Sipes Regional Airport (MKL) to New Madridcar car
    5h 28m
    $200–532

  7. Fly to Williamson County Regional Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Williamson County Regional Airport (MWA)plane plane ORD - MWA
    2. Take the bus from Marathon Gas Station - Marion to Flying J - Matthewsbus bus
    6h 7m
    $144–311

Chicago O'Hare International Airport (ORD) to Cape Girardeau Municipal Airport (CGI) flights

Calendar7Weekly Planes
Duration1h 35mAverage Duration
Ticket$107Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Chicago to New Madrid.ExpandLaunch map view
  • Distance: 405.2 mi
  • Duration: 4h 10m

What companies run services between Chicago, IL, USA and New Madrid, MO, USA?

Tornado Bus Company operates a bus from Tornado Bus Co - Chicago to Flying J - Matthews once daily. Tickets cost $80–100 and the journey takes 7h 24m.

Airlines
Train operators
Bus operators
Ferry operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides