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How to get fromChicago to New Madridby plane, taxi, bus, train, car ferry, or car

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There are 8 ways to get from Chicago to New Madrid by plane, taxi, bus, train, car ferry, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Cape Girardeau Municipal Airport, taxi

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Cape Girardeau Municipal Airport (CGI)plane plane ORD - CGI
    2. Take the taxi from Cape Girardeau Municipal Airport (CGI) to New Madridtaxi taxi
    4h 16m
    $228–375

  2. Fly Chicago O'Hare International Airport to Barkley Regional Airport, drive

    cheapest
    1. Fly from Chicago O'Hare International Airport (ORD) to Barkley Regional Airport (PAH)plane plane ORD - PAH
    2. Drive from Barkley Regional Airport (PAH) to New Madridcar car
    4h 43m
    $66–325

  3. Bus

    1. Take the bus from Tornado Bus Co - Chicago to Flying J - Matthewsbus bus Milwaukee
    9h 2m
    $116–243

  4. Train, car ferry

    1. Take the train from Chicago Union Station to Fulton Amtrak Stationtrain train City of New Orleans
    2. Take the car ferry from Hickman, KY to Dorena, MOcarferry car ferry Dorena-Hickman Ferry
    9h 43m
    $144–298

  5. Drive 412.6 mi

    1. Drive from Chicago to New Madridcar car 412.6 mi
    6h 47m
    $76–109

  6. Fly Chicago O'Hare International Airport to Williamson County Regional Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Williamson County Regional Airport (MWA)plane plane ORD - MWA
    2. Take the bus from Marathon Gas Station - Marion to Flying J - Matthewsbus bus
    5h 58m
    $172–421

  7. Fly Chicago O'Hare International Airport to Mc Kellar-Sipes Regional Airport, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Mc Kellar-Sipes Regional Airport (MKL)plane plane ORD - MKL
    2. Drive from Mc Kellar-Sipes Regional Airport (MKL) to New Madridcar car
    5h 29m
    $116–272

  8. Fly Chicago Midway International Airport to Lambert–St. Louis International Airport, bus, taxi

    1. Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane plane MDW - STL
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    3. Take the taxi from Cape Girardeau to New Madridtaxi taxi
    7h 26m
    $244–773

Chicago O'Hare International Airport (ORD) to Cape Girardeau Municipal Airport (CGI) flights

Calendar7Weekly Planes
Duration1h 40mAverage Duration
Ticket$99Cheapest Price
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Questions & Answers

Map of how to get from Chicago to New Madrid.ExpandLaunch map view
  • Distance: 405.2 mi
  • Duration: 4h 16m

What companies run services between Chicago, IL, USA and New Madrid, MO, USA?

Tornado Bus Company operates a bus from Tornado Bus Co - Chicago to Flying J - Matthews once daily. Tickets cost $75–190 and the journey takes 7h 24m.

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