Rome2Rio

How to get fromChicago to North Carolinaby plane, bus, train (Amtrak), car, or bus (Amtrak, Greyhound)

Find Transport to North Carolina

See all options

There are 10 ways to get from Chicago to North Carolina by plane, bus, train (Amtrak), car, or bus (Amtrak, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Piedmont Triad International Airport

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Piedmont Triad International Airport (GSO)plane plane ORD - GSO
    4h 1m
    $140–640

  2. Fly Chicago O'Hare International Airport to Wilmington International Airport

    cheapest
    1. Fly from Chicago O'Hare International Airport (ORD) to Wilmington International Airport (ILM)plane plane ORD - ILM
    4h 14m
    $96–422

  3. Bus

    1. Take the bus from Chicago to N Wilson Rd & Ferrell Pl - Columbusbus bus Chicago
    2. Take the bus from Columbus to Charlottebus bus Bsb 32
    18h 50m
    $142–270

  4. Train (Amtrak)

    1. Take the train from Chicago Union Station to Carytrain train Floridian
    2. Take the train from Cary to Charlotte Amtrak Stationtrain train Piedmont / ...
    28h 50m
    $404–815

  5. Drive 728.5 mi

    1. Drive from Chicago to Charlottecar car 728.5 mi
    13h 28m
    $133–192

  6. Fly Chicago O'Hare International Airport to Charlotte Douglas International Airport

    1. Fly from Chicago O'Hare International Airport (ORD) to Charlotte Douglas International Airport (CLT)plane plane ORD - CLT
    4h 30m
    $136–418

  7. Fly Chicago Midway International Airport to Charlotte Douglas International Airport

    1. Fly from Chicago Midway International Airport (MDW) to Charlotte Douglas International Airport (CLT)plane plane MDW - CLT
    4h 13m
    $126–708

  8. Fly Chicago Midway International Airport to Raleigh-Durham International Airport

    1. Fly from Chicago Midway International Airport (MDW) to Raleigh-Durham International Airport (RDU)plane plane MDW - RDU
    4h 52m
    $156–308

  9. Fly Chicago O'Hare International Airport to Raleigh-Durham International Airport

    1. Fly from Chicago O'Hare International Airport (ORD) to Raleigh-Durham International Airport (RDU)plane plane ORD - RDU
    5h 15m
    $186–508

  10. Bus via Toledo

    1. Take the bus from Chicago Union Station to Toledobus bus Amtrak Thruway Connecting Service
    2. Take the bus from Toledo Bus Stop to Charlotte Bus Stationbus bus Greyhound US0140
    19h 18m
    $186–309

Chicago to North Carolina by bus

Calendar7Weekly Buses
Duration18h 50mAverage Duration
Ticket$142Cheapest Price
See schedules

Questions & Answers

Map of how to get from Chicago to North Carolina.ExpandLaunch map view
  • Distance: 617.7 mi
  • Duration: 4h 1m

What companies run services between Chicago, IL, USA and North Carolina, USA?

American Airlines, United Airlines, and Delta fly from Chicago O'Hare International Airport (ORD) to Piedmont Triad International Airport (GSO) hourly. Alternatively, you can take a bus from Chicago to Charlotte via Columbus in around 18h 50m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers