There are 7 ways to get from Chicago to Opelousas by plane, taxi, train (Amtrak), bus (Flixbus, Greyhound), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Chicago O'Hare International Airport to Lafayette Regional Airport, taxi
best- Fly from Chicago O'Hare International Airport (ORD) to Lafayette Regional Airport (LFT)plane ORD - LFT
- Take the taxi from Lafayette Regional Airport (LFT) to Opelousastaxi
7h 2m$114–478Train (Amtrak)
- Take the train from Chicago Union Station to New Orleans Union Passenger Terminaltrain City of New Orleans
- Take the train from New Orleans Union Passenger Terminal to Lafayette Amtrak Stationtrain Sunset Limited
24h 30m$364–715Bus
- Take the bus from Chicago Bus Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Baton Rouge Bus Stationbus
- Take the bus from Baton Rouge Bus Station to Opelousasbus
27h 45m$189–341Drive 920.9 mi
- Drive from Chicago to Opelousascar 920.9 mi
16h 47m$169–243Fly Chicago Midway International Airport to Lafayette Regional Airport, taxi
- Fly from Chicago Midway International Airport (MDW) to Lafayette Regional Airport (LFT)plane MDW - LFT
- Take the taxi from Lafayette Regional Airport (LFT) to Opelousastaxi
6h 50m$134–618Fly Chicago Midway International Airport to Louis Armstrong New Orleans International Airport, bus
- Fly from Chicago Midway International Airport (MDW) to Louis Armstrong New Orleans International Airport (MSY)plane MDW - MSY
- Take the bus from New Orleans International Airport to Opelousasbus
9h 19m$160–718Fly Chicago O'Hare International Airport to Louis Armstrong New Orleans International Airport, bus
- Fly from Chicago O'Hare International Airport (ORD) to Louis Armstrong New Orleans International Airport (MSY)plane ORD - MSY
- Take the bus from New Orleans International Airport to Opelousasbus
9h 42m$370–768
Chicago O'Hare International Airport (ORD) to Lafayette Regional Airport (LFT) flights
Questions & Answers
The cheapest way to get from Chicago to Opelousas is to drive which costs $160 - $250 and takes 16h 47m.
The fastest way to get from Chicago to Opelousas is to fly and taxi which takes 6h 50m and costs $130 - $650.
No, there is no direct bus from Chicago station to Opelousas. However, there are services departing from Chicago Bus Station and arriving at Opelousas via St Louis Bus Station and Baton Rouge Bus Station. The journey, including transfers, takes approximately 27h 45m.
No, there is no direct train from Chicago station to Opelousas station. However, there are services departing from Chicago Union Station and arriving at Lafayette Amtrak Station via New Orleans Union Passenger Terminal. The journey, including transfers, takes approximately 24h 30m.
The distance between Chicago and Opelousas is 892 miles. The road distance is 926.2 miles.
The best way to get from Chicago to Opelousas without a car is to train which takes 24h 30m and costs $360 - $750.
It takes approximately 7h 2m to get from Chicago to Opelousas, including transfers.
Chicago to Opelousas bus services, operated by Flixbus USA, depart from Chicago Bus Station.
Chicago to Opelousas train services, operated by Amtrak, depart from Chicago Union Station.
The best way to get from Chicago to Opelousas is to train which takes 24h 30m and costs $360 - $750. Alternatively, you can bus, which costs $180 - $350 and takes 27h 45m.
What companies run services between Chicago, IL, USA and Opelousas, LA, USA?
You can take a train from Chicago Union Station to Opelousas via New Orleans Union Passenger Terminal and Lafayette Amtrak Station in around 24h 30m. Alternatively, you can take a bus from Chicago Bus Station to Opelousas via St Louis Bus Station, Baton Rouge Bus Station, and Opelousas in around 27h 45m.
- Website
- southwest.com
Flights from Chicago Midway International Airport to Louis Armstrong New Orleans International Airport
- Ave. Duration
- 2h 12m
- When
- Every day
- Estimated price
- $120–650
Flights from Chicago Midway International Airport to Louis Armstrong New Orleans International Airport via Nashville
- Ave. Duration
- 4h 31m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $120–650
Flights from Chicago Midway International Airport to Louis Armstrong New Orleans International Airport via St. Louis
- Ave. Duration
- 4h 30m
- When
- Sunday
- Estimated price
- $120–650
Flights from Chicago Midway International Airport to Louis Armstrong New Orleans International Airport via Kansas City
- Ave. Duration
- 4h 45m
- When
- Monday, Thursday, and Friday
- Estimated price
- $150–700
- Website
- delta.com
Flights from Chicago O'Hare International Airport to Lafayette Regional Airport via Atlanta
- Ave. Duration
- 5h 33m
- When
- Every day
- Estimated price
- $100–460
Flights from Chicago Midway International Airport to Lafayette Regional Airport via Atlanta
- Ave. Duration
- 5h 49m
- When
- Every day
- Estimated price
- $120–600
- Website
- united.com
Flights from Chicago O'Hare International Airport to Lafayette Regional Airport via Houston
- Ave. Duration
- 5h 13m
- When
- Every day
- Estimated price
- $100–470
Flights from Chicago O'Hare International Airport to Louis Armstrong New Orleans International Airport
- Ave. Duration
- 2h 32m
- When
- Every day
- Estimated price
- $95–480
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Lafayette Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 34m
- When
- Every day
- Estimated price
- $100–470
Flights from Chicago O'Hare International Airport to Lafayette Regional Airport via Charlotte
- Ave. Duration
- 7h 55m
- When
- Every day
- Estimated price
- $110–550
Flights from Chicago Midway International Airport to Lafayette Regional Airport via Charlotte
- Ave. Duration
- 5h 55m
- When
- Saturday and Sunday
- Estimated price
- $140–650
Flights from Chicago O'Hare International Airport to Louis Armstrong New Orleans International Airport
- Ave. Duration
- 2h 26m
- When
- Every day
- Estimated price
- $95–480
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to New Orleans Union Passenger Terminal
- Ave. Duration
- 19h 42m
- Frequency
- Once daily
- Estimated price
- $300–650
- Website
- https://www.amtrak.com/home.html
Train from New Orleans Union Passenger Terminal to Lafayette Amtrak Station
- Ave. Duration
- 3h 24m
- Frequency
- 3 times a week
- Estimated price
- $45–95
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Chicago Bus Station to St Louis Bus Station
- Ave. Duration
- 5h 55m
- Frequency
- Twice daily
- Estimated price
- $45–80
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from St Louis Bus Station to Baton Rouge Bus Station
- Ave. Duration
- 18h 30m
- Frequency
- Once daily
- Estimated price
- $120–230
- Website
- https://www.greyhound.com/
Bus from Baton Rouge Bus Station to Opelousas
- Ave. Duration
- 1h 15m
- Frequency
- 6 times a week
- Estimated price
- $9–18
- Website
- https://www.greyhound.com/
Bus from New Orleans International Airport to Opelousas
- Ave. Duration
- 4h 10m
- Frequency
- Once daily
- Estimated price
- $26–50
- Website
- https://www.greyhound.com/
Bus from New Orleans International Airport to Opelousas
- Ave. Duration
- 4h 10m
- Frequency
- Once daily
- Estimated price
- $26–50
- Website
- https://www.greyhound.com/
- Ave. Duration
- 28 min
- Estimated price
- $11–13
Power Electric Taxi
- Phone
- +1-337-534-0188
Power Electric Taxi
- Phone
- +1-337-534-0188
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More Questions & Answers
Chicago to Opelousas bus services, operated by Flixbus USA, arrive at St Louis Bus Station.
Chicago to Opelousas train services, operated by Amtrak, arrive at New Orleans Union Passenger Terminal station.
Yes, the driving distance between Chicago to Opelousas is 926 miles. It takes approximately 16h 47m to drive from Chicago to Opelousas.
Book your Chicago to Opelousas bus tickets online with Omio.
There are 14+ hotels available in Opelousas.






