There are 4 ways to get from Chicago to Orangeburg by plane, taxi, bus (Amtrak, Greyhound, Flixbus), train (Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly, taxi
best- Fly from Chicago O'Hare International Airport (ORD) to Columbia (CAE)plane ORD - CAE
- Take the taxi from Columbia-Airport-CAE to Orangeburgtaxi
4h 35m$292–1,055Drive 800.1 mi
cheapest- Drive from Chicago to Orangeburgcar 800.1 mi
14h 47m$146–211Bus
- Take the bus from Chicago Union Station to Toledobus
- Take the bus from Toledo Bus Stop to Charlotte Bus Stationbus
- Take the bus from Charlotte Bus Station to Orangeburgbus
24h 36m$221–373Train (Amtrak)
- Take the train from Chicago Union Station to Denmark Amtrak Stationtrain Floridian
30h 22m$500–950
Chicago O'Hare International Airport (ORD) to Columbia (CAE) flights
Questions & Answers
The cheapest way to get from Chicago to Orangeburg is to drive which costs $140 - $220 and takes 14h 47m.
The fastest way to get from Chicago to Orangeburg is to fly and taxi which takes 4h 35m and costs $290 - $1,100.
No, there is no direct bus from Chicago station to Orangeburg. However, there are services departing from Chicago Union Station and arriving at Orangeburg via Toledo Bus Stop and Charlotte Bus Station. The journey, including transfers, takes approximately 24h 36m.
No, there is no direct train from Chicago station to Orangeburg station. However, there are services departing from Chicago Union Station and arriving at Denmark Amtrak Station via . The journey, including transfers, takes approximately 30h 22m.
The distance between Chicago and Orangeburg is 727 miles. The road distance is 804.8 miles.
The best way to get from Chicago to Orangeburg without a car is to bus which takes 24h 36m and costs $220 - $380.
It takes approximately 4h 35m to get from Chicago to Orangeburg, including transfers.
Chicago to Orangeburg bus services, operated by Amtrak, depart from Chicago Union Station.
Chicago to Orangeburg train services, operated by Amtrak, depart from Chicago Union Station.
The best way to get from Chicago to Orangeburg is to bus which takes 24h 36m and costs $220 - $380. Alternatively, you can train, which costs $500 - $950 and takes 30h 22m.
What companies run services between Chicago, IL, USA and Orangeburg, SC, USA?
You can take a bus from Chicago Union Station to Orangeburg via Toledo Bus Stop, Charlotte Bus Station, and Orangeburg in around 24h 36m. Alternatively, Amtrak operates a train from Chicago Union Station to Denmark Amtrak Station once daily. Tickets cost $430–900 and the journey takes 29h 50m.
- Website
- united.com
Flights from Chicago O'Hare International Airport to Columbia
- Ave. Duration
- 2h 16m
- When
- Every day
- Estimated price
- $170–900
Flights from Chicago O'Hare International Airport to Columbia via Washington Dulles
- Ave. Duration
- 4h 39m
- When
- Every day
- Estimated price
- $230–1,100
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Columbia
- Ave. Duration
- 2h 8m
- When
- Every day
- Estimated price
- $170–900
Flights from Chicago O'Hare International Airport to Columbia via Charlotte
- Ave. Duration
- 4h 21m
- When
- Every day
- Estimated price
- $180–900
- Website
- delta.com
Flights from Chicago O'Hare International Airport to Columbia via Atlanta
- Ave. Duration
- 4h 11m
- When
- Every day
- Estimated price
- $190–1,000
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Denmark Amtrak Station
- Ave. Duration
- 29h 50m
- Frequency
- Once daily
- Estimated price
- $430–900
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Chicago Union Station to Toledo
- Ave. Duration
- 3h 58m
- Frequency
- Twice a week
- Estimated price
- $85–130
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Toledo Bus Stop to Charlotte Bus Station
- Ave. Duration
- 14h 35m
- Frequency
- Once daily
- Estimated price
- $100–190
- Website
- https://www.greyhound.com/
Bus from Charlotte Bus Station to Orangeburg
- Ave. Duration
- 4h
- Frequency
- Twice daily
- Estimated price
- $26–50
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Charlotte Bus Station to Orangeburg
- Ave. Duration
- 2h 35m
- Frequency
- Once daily
- Estimated price
- $26–45
- Schedules at
- flixbus.com
- Ave. Duration
- 42 min
- Estimated price
- $120–150
Checker Yellow Cabs
- Phone
- +1 803-799-3311
- Website
- checkeryellowcab.com
Want to know more about travelling around United States
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More Questions & Answers
Chicago to Orangeburg bus services, operated by Amtrak, arrive at Toledo station.
Orangeburg is 1h ahead of Chicago. It is currently 6:50 PM in Chicago and 7:50 PM in Orangeburg.
Chicago to Orangeburg train services, operated by Amtrak, arrive at Denmark Amtrak Station.
Yes, the driving distance between Chicago to Orangeburg is 805 miles. It takes approximately 14h 47m to drive from Chicago to Orangeburg.
Book your Chicago to Orangeburg bus tickets online with Omio.
There are 21+ hotels available in Orangeburg.








