There are 8 ways to get from Chicago to Palo Alto by plane, bus (Greyhound), train, subway, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Chicago Midway International Airport to Norman Y. Mineta San José International Airport
best- Fly from Chicago Midway International Airport (MDW) to Norman Y. Mineta San José International Airport (SJC)plane MDW - SJC
7h$210–864Fly Chicago O'Hare International Airport to San Francisco International Airport
cheapest- Fly from Chicago O'Hare International Airport (ORD) to San Francisco International Airport (SFO)plane ORD - SFO
7h 21m$136–303Bus
- Take the bus from Chicago Bus Station to Denver Union Stationbus
- Take the bus from Denver Union Station to Sparks Transit Centerbus
- Take the bus from Sparks Transit Center to San Francisco Bus Stationbus
- Take the bus from Salesforce Transit Center- Bay 37 to Clarke Ave & O'Connor St-Ravenswood Shopping Ctrbus Epx
2d 5h$372–700Train, BART
- Take the train from Chicago Union Station to Richmondtrain California Zephyr
- Take the subway from Richmond to Millbraesubway Red-S
2d 7h$800–1,594Drive 2,150.4 mi
- Drive from Chicago to Palo Altocar 2,150.4 mi
33h 29m$393–567Fly Chicago Midway International Airport to San Francisco International Airport
- Fly from Chicago Midway International Airport (MDW) to San Francisco International Airport (SFO)plane MDW - SFO
7h 3m$216–463Fly Chicago O'Hare International Airport to Norman Y. Mineta San José International Airport
- Fly from Chicago O'Hare International Airport (ORD) to Norman Y. Mineta San José International Airport (SJC)plane ORD - SJC
7h 33m$170–564Fly Chicago Midway International Airport to Oakland International Airport, train
- Fly from Chicago Midway International Airport (MDW) to Oakland International Airport (OAK)plane MDW - OAK
- Take the train from Oakland Coliseum/Airport Amtrak to Santa Clara Amtraktrain
8h 38m$240–939
Chicago to Palo Alto by bus
Questions & Answers
The cheapest way to get from Chicago to Palo Alto is to fly which costs $130 - $310 and takes 7h 21m.
The fastest way to get from Chicago to Palo Alto is to fly which takes 7h and costs $210 - $900.
No, there is no direct bus from Chicago station to Palo Alto. However, there are services departing from Chicago Bus Station and arriving at Clarke Ave & O'Connor St-Ravenswood Shopping Ctr via Denver Union Station, Sparks Transit Center and Salesforce Transit Center- Bay 37. The journey, including transfers, takes approximately 2 days 5h.
No, there is no direct train from Chicago station to Palo Alto. However, there are services departing from Chicago Union Station and arriving at Millbrae via Richmond. The journey, including transfers, takes approximately 2 days 7h.
The distance between Chicago and Palo Alto is 1873 miles. The road distance is 2162.9 miles.
The best way to get from Chicago to Palo Alto without a car is to bus which takes 2 days 5h and costs $370 - $700.
It takes approximately 7h to get from Chicago to Palo Alto, including transfers.
Chicago to Palo Alto bus services, operated by Greyhound USA, depart from Chicago Bus Station.
Chicago to Palo Alto train services, operated by Amtrak, depart from Chicago Union Station.
The best way to get from Chicago to Palo Alto is to fly which takes 7h and costs $210 - $900. Alternatively, you can bus, which costs $370 - $700 and takes 2 days 5h.
What companies run services between Chicago, IL, USA and Palo Alto, CA, USA?
Southwest Airlines flies from Chicago Midway International Airport (MDW) to Norman Y. Mineta San José International Airport (SJC) 5 times a day. Alternatively, you can take a bus from Chicago Bus Station to Clarke Ave & O'Connor St-Ravenswood Shopping Ctr via Denver Union Station, Sparks Transit Center, San Francisco Bus Station, and Salesforce Transit Center- Bay 37 in around 2d 5h.
- Website
- southwest.com
Flights from Chicago Midway International Airport to Norman Y. Mineta San José International Airport
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- $200–850
Flights from Chicago Midway International Airport to Norman Y. Mineta San José International Airport via Denver
- Ave. Duration
- 6h 21m
- When
- Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- $210–850
Flights from Chicago Midway International Airport to Norman Y. Mineta San José International Airport via Las Vegas
- Ave. Duration
- 6h 23m
- When
- Every day
- Estimated price
- $210–900
Flights from Chicago Midway International Airport to Norman Y. Mineta San José International Airport via Reno
- Ave. Duration
- 6h 15m
- When
- Monday, Thursday, and Friday
- Estimated price
- $210–850
Flights from Chicago Midway International Airport to San Francisco International Airport
- Ave. Duration
- 4h 33m
- When
- Every day
- Estimated price
- $140–600
Flights from Chicago Midway International Airport to San Francisco International Airport via Denver
- Ave. Duration
- 6h 56m
- When
- Every day
- Estimated price
- $140–600
Flights from Chicago Midway International Airport to San Francisco International Airport via Las Vegas
- Ave. Duration
- 7h 12m
- When
- Every day
- Estimated price
- $140–600
Flights from Chicago Midway International Airport to Oakland International Airport
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- $220–900
Flights from Chicago Midway International Airport to Oakland International Airport via Denver
- Ave. Duration
- 6h 23m
- When
- Tuesday, Wednesday, Sunday, and Saturday
- Estimated price
- $220–900
Flights from Chicago Midway International Airport to Oakland International Airport via Las Vegas
- Ave. Duration
- 6h 21m
- When
- Every day
- Estimated price
- $220–950
Flights from Chicago Midway International Airport to Oakland International Airport via Salt Lake City
- Ave. Duration
- 6h 40m
- When
- Tuesday and Wednesday
- Estimated price
- $220–900
- Website
- united.com
Flights from Chicago O'Hare International Airport to San Francisco International Airport
- Ave. Duration
- 4h 46m
- When
- Every day
- Estimated price
- $100–440
Flights from Chicago O'Hare International Airport to San Francisco International Airport via Denver
- Ave. Duration
- 6h 26m
- When
- Every day
- Estimated price
- $100–440
Flights from Chicago O'Hare International Airport to Norman Y. Mineta San José International Airport
- Ave. Duration
- 4h 46m
- When
- Every day
- Estimated price
- $160–650
Flights from Chicago O'Hare International Airport to Norman Y. Mineta San José International Airport via Denver
- Ave. Duration
- 6h 37m
- When
- Every day
- Estimated price
- $160–650
- Website
- aa.com
Flights from Chicago O'Hare International Airport to San Francisco International Airport
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- $100–440
- Website
- delta.com
Flights from Chicago O'Hare International Airport to Norman Y. Mineta San José International Airport via Salt Lake City
- Ave. Duration
- 6h 22m
- When
- Every day
- Estimated price
- $160–650
Flights from Chicago O'Hare International Airport to Norman Y. Mineta San José International Airport via Los Angeles
- Ave. Duration
- 7h 37m
- When
- Every day
- Estimated price
- $170–700
- Website
- flyfrontier.com
Flights from Chicago O'Hare International Airport to Norman Y. Mineta San José International Airport via Las Vegas
- Ave. Duration
- 8h 2m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $160–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Richmond
- Ave. Duration
- 2d 4h
- Frequency
- Once daily
- Estimated price
- $750–1,600
- Website
- https://www.amtrak.com/home.html
Train from Oakland Coliseum/Airport Amtrak to Santa Clara Amtrak
- Ave. Duration
- 51 min
- Frequency
- Every 4 hours
- Estimated price
- $12–25
- Website
- https://www.amtrak.com/home.html
- Phone
- +1-510-464-6000
- Website
- bart.gov
Subway from Richmond to Millbrae
- Ave. Duration
- 1h 16m
- Frequency
- Every 30 minutes
- Estimated price
- $12–16
- Website
- https://www.bart.gov
- Adult Single Ride
- $12–16
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Chicago Bus Station to Denver Union Station
- Ave. Duration
- 21h 35m
- Frequency
- Once daily
- Estimated price
- $160–310
- Website
- https://www.greyhound.com/
Bus from Denver Union Station to Sparks Transit Center
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- $170–320
- Website
- https://www.greyhound.com/
Bus from Sparks Transit Center to San Francisco Bus Station
- Ave. Duration
- 6h 10m
- Frequency
- Twice daily
- Estimated price
- $35–70
- Website
- https://www.greyhound.com/
- Website
- samtrans.com
Bus from Salesforce Transit Center- Bay 37 to Clarke Ave & O'Connor St-Ravenswood Shopping Ctr
- Ave. Duration
- 1h 36m
- Frequency
- 4 times a day
- Estimated price
- $2–5
- Website
- http://www.samtrans.com
- Website
- http://www.samtrans.com
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More Questions & Answers
Chicago to Palo Alto bus services, operated by Greyhound USA, arrive at Denver Union Station.
Palo Alto is 2h behind Chicago. It is currently 7:56 AM in Chicago and 5:56 AM in Palo Alto.
Chicago to Palo Alto train services, operated by Amtrak, arrive at Richmond station.
Yes, the driving distance between Chicago to Palo Alto is 2163 miles. It takes approximately 33h 29m to drive from Chicago to Palo Alto.
There are 455+ hotels available in Palo Alto.











