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How to get fromChicago to Panama Cityby plane, car, or train

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There are 5 ways to get from Chicago to Panama City by plane, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Chicago O'Hare International Airport

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Tocumen International Airport (PTY)plane plane ORD - PTY
    9h 2m
    $160–593

  2. Drive  6,059.3 km

    1. Drive from Chicago to Panama Citycar car 6,059.3 km
    3d 5h
    $720–1,040

  3. Fly from Chicago Midway International Airport

    1. Fly from Chicago Midway International Airport (MDW) to Tocumen International Airport (PTY)plane plane MDW - PTY
    10h 12m
    $250–943

  4. Train to South Bend, fly

    1. Take the train from Van Buren St. to South Bend Airporttrain train
    2. Fly from South Bend (SBN) to Tocumen International Airport (PTY)plane plane SBN - PTY
    12h 47m
    $203–704

  5. Train to General Mitchell International Airport, fly

    1. Take the train from Chicago Union Station to Milwaukeetrain train
    2. Fly from General Mitchell International Airport (MKE) to Tocumen International Airport (PTY)plane plane MKE - PTY
    12h 4m
    $307–1,024

Chicago O'Hare International Airport (ORD) to Tocumen International Airport (PTY) flights

Calendar45Weekly Planes
Duration7h 6mAverage Duration
Ticket$128Cheapest Price
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Comparing Your Travel Options

Map of how to get from Chicago to Panama City.ExpandLaunch map view
  • Distance: 3,806.2 km
  • Duration: 9h 2m

What companies run services between Chicago, IL, USA and Panama City, Panama?

Copa Airlines, United Airlines, and American Airlines fly from Chicago O'Hare International Airport (ORD) to Tocumen International Airport (PTY) every 4 hours.

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Want to know more about travelling around Panama

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

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