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How to get fromChicago to Panama City Beachby plane, bus (Greyhound, Flixbus), train, bus, or car

Find Transport to Panama City Beach

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There are 9 ways to get from Chicago to Panama City Beach by plane, bus (Greyhound, Flixbus), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago Midway International Airport to Northwest Florida Beaches International Airport

    best
    1. Fly from Chicago Midway International Airport (MDW) to Northwest Florida Beaches International Airport (ECP)plane plane MDW - ECP
    4h 7m
    $152–620

  2. Fly Chicago O'Hare International Airport to Destin–Fort Walton Beach Airport, drive

    cheapest
    1. Fly from Chicago O'Hare International Airport (ORD) to Destin–Fort Walton Beach Airport (VPS)plane plane ORD - VPS
    2. Drive from Destin–Fort Walton Beach Airport (VPS) to Panama City Beachcar car
    5h 36m
    $92–421

  3. Bus

    1. Take the bus from Chicago Bus Station to Nashville Bus Stationbus bus
    2. Take the bus from Nashville Bus Station to Tallahasseebus bus
    3. Take the bus from Tallahassee to Panama City Beach Bus Stationbus bus
    23h 34m
    $175–339

  4. Train, bus via New Orleans

    1. Take the train from Chicago Union Station to New Orleans Union Passenger Terminaltrain train
    2. Take the bus from New Orleans Bus Station to Mobile Bus Stationbus bus
    3. Take the bus from Mobile Bus Station to Panama City Beach Bus Stationbus bus
    27h 46m
    $361–717

  5. Drive 888.7 mi

    1. Drive from Chicago to Panama City Beachcar car 888.7 mi
    16h 47m
    $163–235

  6. Fly Chicago O'Hare International Airport to Northwest Florida Beaches International Airport

    1. Fly from Chicago O'Hare International Airport (ORD) to Northwest Florida Beaches International Airport (ECP)plane plane ORD - ECP
    4h 45m
    $132–470

  7. Fly Chicago Midway International Airport to Destin–Fort Walton Beach Airport, drive

    1. Fly from Chicago Midway International Airport (MDW) to Destin–Fort Walton Beach Airport (VPS)plane plane MDW - VPS
    2. Drive from Destin–Fort Walton Beach Airport (VPS) to Panama City Beachcar car
    5h 10m
    $112–521

  8. Bus via Atlanta

    1. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Tallahasseebus bus
    3. Take the bus from Tallahassee to Panama City Beach Bus Stationbus bus
    24h 49m
    $185–354

  9. Train, bus

    1. Take the train from Chicago Union Station to Jacksonvilletrain train Floridian
    2. Take the bus from Jacksonville to Panama City Beach Bus Stationbus bus Greyhound US0760S
    43h 51m
    $559–1,119

Chicago Midway International Airport (MDW) to Northwest Florida Beaches International Airport (ECP) flights

Calendar36Weekly Planes
Duration3h 49mAverage Duration
Ticket$104Cheapest Price
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Questions & Answers

Map of how to get from Chicago to Panama City Beach.ExpandLaunch map view
  • Distance: 827.2 mi
  • Duration: 4h 7m

What companies run services between Chicago, IL, USA and Panama City Beach, FL, USA?

Southwest Airlines and Delta fly from Chicago Midway International Airport (MDW) to Northwest Florida Beaches International Airport (ECP) 5 times a day. Alternatively, you can take a bus from Chicago Bus Station to Panama City Beach via Nashville Bus Station, Tallahassee, and Panama City Beach Bus Station in around 23h 34m.

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