Rome2Rio

How to get fromChicago to Prairie du Chienby train, bus, car, or plane

Find Transport to Prairie du Chien

See all options

There are 8 ways to get from Chicago to Prairie du Chien by train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus, drive

    best
    1. Take the train from Chicago Union Station to Milwaukeetrain train
    2. Take the bus from Milwaukee to UW La Crossebus bus
    3. Drive from UW La Crosse to Prairie du Chiencar car
    7h 22m
    $88–146

  2. Drive 222.8 mi

    cheapest
    1. Drive from Chicago to Prairie du Chiencar car 222.8 mi
    4h 51m
    $41–59

  3. Fly to La Crosse, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to La Crosse (LSE)plane plane ORD - LSE
    2. Drive from La-Crosse-Airport-LSE to Prairie du Chiencar car
    4h 35m
    $54–303

  4. Bus, drive

    1. Take the bus from Chicago Bus Station to Wisconsin Dellsbus bus
    2. Take the bus from Wisconsin Dells to La Crossebus bus
    3. Drive from La Crosse to Prairie du Chiencar car
    8h 11m
    $72–121

  5. Bus, drive via Madison

    1. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    2. Take the bus from Madison to La Crossebus bus
    3. Drive from La Crosse to Prairie du Chiencar car
    8h 26m
    $71–125

  6. Fly to The Eastern Iowa Airport, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to The Eastern Iowa Airport (CID)plane plane ORD - CID
    2. Drive from Cedar-Rapids-Airport-CID to Prairie du Chiencar car
    5h 11m
    $56–303

  7. Fly to Waterloo Municipal Airport, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Waterloo Municipal Airport (ALO)plane plane ORD - ALO
    2. Drive from Waterloo Municipal Airport (ALO) to Prairie du Chiencar car
    5h 8m
    $58–310

  8. Fly to Quad City International Airport, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Quad City International Airport (MLI)plane plane ORD - MLI
    2. Drive from Moline-Airport-MLI to Prairie du Chiencar car
    5h 47m
    $62–305

Chicago O'Hare International Airport (ORD) to La Crosse (LSE) flights

Calendar28Weekly Planes
Duration1h 22mAverage Duration
Ticket$40Cheapest Price
See schedules

Questions & Answers

Map of how to get from Chicago to Prairie du Chien.ExpandLaunch map view
  • Distance: 347 mi
  • Duration: 7h 22m

What companies run services between Chicago, IL, USA and Prairie du Chien, WI, USA?

There is no direct connection from Chicago to Prairie du Chien. However, you can take the train to Milwaukee, walk to Milwaukee, take the bus to UW La Crosse, then drive to Prairie du Chien. Alternatively, you can drive from Chicago to Prairie du Chien in around 4h 51m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound