There are 5 ways to get from Chicago to Saint Charles by plane, train (Amtrak), bus, taxi, car, or subway
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Chicago O'Hare International Airport
best- Fly from Chicago O'Hare International Airport (ORD) to Des Moines (DSM)plane ORD - DSM
3h 43m$128–560Drive 360.1 mi
cheapest- Drive from Chicago to Saint Charlescar 360.1 mi
6h 6m$66–95Train (Amtrak)
- Take the train from Chicago Union Station to Osceola Amtraktrain California Zephyr
6h 45m$159–296Bus, taxi
- Take the bus from Chicago Bus Station to Des Moinesbus Greyhound US0123S / ...
- Take the taxi from Des Moines to Saint Charlestaxi
7h 11m$126–185Subway to Chicago Midway International Airport, fly
- Take the subway from Adams/Wabash to Midwaysubway
- Fly from Chicago Midway International Airport (MDW) to Des Moines (DSM)plane MDW - DSM
3h 25m$148–720
Chicago O'Hare International Airport (ORD) to Des Moines (DSM) flights
Questions & Answers
The cheapest way to get from Chicago to Saint Charles is to drive which costs $65 - $95 and takes 6h 6m.
The fastest way to get from Chicago to Saint Charles is to subway and fly which takes 3h 25m and costs $140 - $750.
No, there is no direct train from Chicago station to Saint Charles. However, there are services departing from Chicago Union Station and arriving at Osceola Amtrak via . The journey, including transfers, takes approximately 6h 45m.
The distance between Chicago and Saint Charles is 340 miles. The road distance is 362.2 miles.
The best way to get from Chicago to Saint Charles without a car is to train which takes 6h 45m and costs $150 - $300.
It takes approximately 3h 43m to get from Chicago to Saint Charles, including transfers.
Chicago to Saint Charles train services, operated by Amtrak, depart from Chicago Union Station.
The best way to get from Chicago to Saint Charles is to fly which takes 3h 43m and costs $120 - $600. Alternatively, you can train, which costs $150 - $300 and takes 6h 45m.
Chicago to Saint Charles train services, operated by Amtrak, arrive at Osceola Amtrak station.
Yes, the driving distance between Chicago to Saint Charles is 362 miles. It takes approximately 6h 6m to drive from Chicago to Saint Charles.
What companies run services between Chicago, IL, USA and Saint Charles, IA, USA?
American Airlines and United Airlines fly from Chicago O'Hare International Airport (ORD) to Des Moines (DSM) every 3 hours. Alternatively, Amtrak operates a train from Chicago Union Station to Osceola Amtrak once daily. Tickets cost $110–240 and the journey takes 6h 23m.
- Website
- southwest.com
Flights from Chicago Midway International Airport to Des Moines
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- $95–650
- Website
- united.com
Flights from Chicago O'Hare International Airport to Des Moines
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $75–490
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Des Moines
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $75–490
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to Osceola Amtrak
- Ave. Duration
- 6h 23m
- Frequency
- Once daily
- Estimated price
- $110–240
- Website
- Amtrak
- Phone
- +1 888-968-7282
- Website
- Chicago Transit Authority
Subway from Adams/Wabash to Midway
- Ave. Duration
- 23 min
- Frequency
- Every 15 minutes
- Estimated price
- $2–5
- Website
- Chicago Transit Authority
- Schedules at
- Chicago Transit Authority Schedules & Routes
- Adult
- $2–5
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 6h 30m
- Frequency
- 5 times a day
- Estimated price
- $50–95
- Website
- Greyhound
- Ave. Duration
- 41 min
- Estimated price
- $75–90
Capitol Cab
- Phone
- +1 515-243-1111
Freedom Taxicab
- Phone
- +1 515-289-9800
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More Questions & Answers
There are six+ hotels available in Saint Charles.













