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How to get fromChicago to San Diego Airport (SAN)by plane, bus (Flixbus, Greyhound), train, bus, or car

Find Transport to San Diego Airport (SAN)

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There are 6 ways to get from Chicago to San Diego Airport (SAN) by plane, bus (Flixbus, Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Chicago Midway International Airport

    best
    1. Fly from Chicago Midway International Airport (MDW) to San Diego International Airport (SAN)plane plane MDW - SAN
    5h 39m
    $172–755

  2. Fly from Chicago O'Hare International Airport

    cheapest
    1. Fly from Chicago O'Hare International Airport (ORD) to San Diego International Airport (SAN)plane plane ORD - SAN
    5h 59m
    $142–605

  3. Bus

    1. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Phoenix Bus Stationbus bus
    3. Take the bus from Phoenix Bus Station to San Diego Greyhound Bus Stopbus bus
    46h 10m
    $323–628

  4. Train, bus

    1. Take the train from Chicago Union Station to San Bernardinotrain train Southwest Chief
    2. Take the bus from San Bernardino Downtown Transit Center to San Diegobus bus FlixBus 2015 / ...
    46h 19m
    $681–1,421

  5. Drive 2,075.9 mi

    1. Drive from Chicago to San Diego Airport (SAN)car car 2,075.9 mi
    32h 38m
    $379–548

  6. Train to General Mitchell International Airport, fly

    1. Take the train from Chicago Union Station to Milwaukeetrain train
    2. Fly from General Mitchell International Airport (MKE) to San Diego International Airport (SAN)plane plane MKE - SAN
    7h 3m
    $228–969

Chicago to San Diego Airport (SAN) by bus

Calendar7Weekly Buses
Duration46h 10mAverage Duration
Ticket$323Cheapest Price
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Questions & Answers

Map of how to get from Chicago to San Diego Airport (SAN).ExpandLaunch map view
  • Distance: 1,737 mi
  • Duration: 5h 39m

What companies run services between Chicago, IL, USA and San Diego Airport (SAN), USA?

Southwest Airlines flies from Chicago Midway International Airport (MDW) to San Diego International Airport (SAN) every 4 hours. Alternatively, you can take a bus from Chicago Bus Station to Terminal 1 Transportation Island via St Louis Bus Station, Phoenix Bus Station, San Diego Greyhound Bus Stop, and Old Town Transit Center in around 46h 10m.

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