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How to get fromChicago to San Ysidro Port of Entryby plane, bus (Flixbus, Greyhound), train (Amtrak), car, train, or bus

Find Transport to San Ysidro Port of Entry

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There are 7 ways to get from Chicago to San Ysidro Port of Entry by plane, bus (Flixbus, Greyhound), train (Amtrak), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Chicago Midway International Airport

    best
    1. Fly from Chicago Midway International Airport (MDW) to San Diego International Airport (SAN)plane plane MDW - SAN
    7h 7m
    $176–775

  2. Fly from Chicago O'Hare International Airport

    cheapest
    1. Fly from Chicago O'Hare International Airport (ORD) to San Diego International Airport (SAN)plane plane ORD - SAN
    7h 27m
    $146–625

  3. Bus

    1. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Phoenix Bus Stationbus bus
    3. Take the bus from Phoenix Bus Station to San Ysidro Bus Terminalbus bus
    46h 22m
    $323–628

  4. Train (Amtrak)

    1. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain train Southwest Chief
    2. Take the train from Fullerton Amtrak Station to San Diego Old Town Transportation Centertrain train Pacific Surfliner
    46h 59m
    $708–1,498

  5. Drive 2,089.1 mi

    1. Drive from Chicago to San Ysidro Port of Entrycar car 2,089.1 mi
    32h 49m
    $382–551

  6. Train to General Mitchell International Airport, fly

    1. Take the train from Chicago Union Station to Milwaukeetrain train
    2. Fly from General Mitchell International Airport (MKE) to San Diego International Airport (SAN)plane plane MKE - SAN
    8h 31m
    $232–989

  7. Train, bus

    1. Take the train from Chicago Union Station to Yuma Amtraktrain train
    2. Take the bus from 3rd Street @ Gila Street to William Brook Ave @ B Streetbus bus 95
    3. Take the bus from San Luis Río Colorado to Mexicalibus bus
    4. Take the bus from Mexicali to Tijuanabus bus
    2d 18h
    $783–1,691

Chicago to San Ysidro Port of Entry by bus and foot

Calendar7Weekly Services
Duration46h 22mAverage Duration
Ticket$323Cheapest Price
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Questions & Answers

Map of how to get from Chicago to San Ysidro Port of Entry.ExpandLaunch map view
  • Distance: 1,758.1 mi
  • Duration: 7h 7m

What companies run services between Chicago, IL, USA and San Ysidro Port of Entry, CA, USA?

Southwest Airlines flies from Chicago Midway International Airport (MDW) to San Diego International Airport (SAN) every 4 hours. Alternatively, you can take a bus from Chicago Bus Station to San Ysidro Port of Entry via St Louis Bus Station, Phoenix Bus Station, and San Ysidro Bus Terminal in around 46h 22m.

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