There are 7 ways to get from Chicago to Sanford by plane, train, bus (Greyhound, Flixbus), train (Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Chicago Midway International Airport to Orlando, train
best- Fly from Chicago Midway International Airport (MDW) to Orlando (MCO)plane MDW - MCO
- Take the train from Sand Lake Road to Sanfordtrain
6h 16m$208–502Fly Chicago O'Hare International Airport to Orlando, train
cheapest- Fly from Chicago O'Hare International Airport (ORD) to Orlando (MCO)plane ORD - MCO
- Take the train from Sand Lake Road to Sanfordtrain
6h 41m$78–612Bus
- Take the bus from Chicago Bus Station to Washington Union Stationbus Greyhound US0164
- Take the bus from Washington Union Station to Deltonabus FlixBus N2473
34h 5m$252–441Train (Amtrak)
- Take the train from Chicago Union Station to Delandtrain Floridian
38h 29m$534–1,100Drive 1,101.7 mi
- Drive from Chicago to Sanfordcar 1,101.7 mi
20h 4m$202–291Train to South Bend, fly to Orlando Sanford
- Take the train from Van Buren St. to South Bend Airporttrain
- Fly from South Bend (SBN) to Orlando Sanford (SFB)plane SBN - SFB
5h 30m$113–514Train to General Mitchell International Airport, fly to Orlando, train
- Take the train from Chicago Union Station to Milwaukeetrain
- Fly from General Mitchell International Airport (MKE) to Orlando (MCO)plane MKE - MCO
- Take the train from Sand Lake Road to Sanfordtrain
7h 54m$324–1,177
Chicago to Sanford by train (Amtrak)
Questions & Answers
The cheapest way to get from Chicago to Sanford is to fly and train which costs $75 - $650 and takes 6h 41m.
The fastest way to get from Chicago to Sanford is to train and fly which takes 5h 30m and costs $110 - $550.
No, there is no direct bus from Chicago station to Sanford. However, there are services departing from Chicago Bus Station and arriving at Deltona via Washington Union Station. The journey, including transfers, takes approximately 34h 5m.
No, there is no direct train from Chicago station to Sanford. However, there are services departing from Chicago Union Station and arriving at Sanford via DeLand. The journey, including transfers, takes approximately 38h 29m.
The distance between Chicago and Sanford is 1043 miles. The road distance is 1108.2 miles.
The best way to get from Chicago to Sanford without a car is to bus which takes 34h 5m and costs $250 - $450.
It takes approximately 6h 16m to get from Chicago to Sanford, including transfers.
Chicago to Sanford bus services, operated by Greyhound USA, depart from Chicago Bus Station.
Chicago to Sanford train services, operated by Amtrak, depart from Chicago Union Station.
The best way to get from Chicago to Sanford is to bus which takes 34h 5m and costs $250 - $450. Alternatively, you can train, which costs $500 - $1,100 and takes 38h 29m.
What companies run services between Chicago, IL, USA and Sanford, FL, USA?
You can take a bus from Chicago Bus Station to Sanford via Washington Union Station and Deltona in around 34h 5m. Alternatively, Amtrak operates a train from Chicago Union Station to Deland once daily. Tickets cost $500–1,100 and the journey takes 37h 13m.
- Website
- southwest.com
Flights from Chicago Midway International Airport to Orlando
- Ave. Duration
- 2h 35m
- When
- Every day
- Estimated price
- $110–550
Flights from Chicago Midway International Airport to Orlando via Nashville
- Ave. Duration
- 4h 20m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $110–550
Flights from Chicago Midway International Airport to Orlando via Covington
- Ave. Duration
- 4h 30m
- When
- Saturday
- Estimated price
- $110–550
Flights from General Mitchell International Airport to Orlando
- Ave. Duration
- 2h 43m
- When
- Every day
- Estimated price
- $130–650
Flights from General Mitchell International Airport to Orlando via Nashville
- Ave. Duration
- 4h 35m
- When
- Saturday
- Estimated price
- $140–650
Flights from General Mitchell International Airport to Orlando via Chicago Midway International Airport
- Ave. Duration
- 4h 36m
- When
- Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- $130–650
Flights from General Mitchell International Airport to Orlando via St. Louis
- Ave. Duration
- 4h 35m
- When
- Monday, Thursday, and Friday
- Estimated price
- $150–700
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Orlando
- Ave. Duration
- 2h 48m
- When
- Every day
- Estimated price
- $90–430
- Website
- united.com
Flights from Chicago O'Hare International Airport to Orlando
- Ave. Duration
- 2h 54m
- When
- Every day
- Estimated price
- $90–430
- Website
- allegiantair.com
Flights from South Bend to Orlando Sanford
- Ave. Duration
- 2h 26m
- When
- Thursday, Sunday, Monday, and Friday
- Estimated price
- $100–500
- Website
- flyfrontier.com
Flights from Chicago O'Hare International Airport to Orlando
- Ave. Duration
- 3h 7m
- When
- Every day
- Estimated price
- $70–350
Flights from General Mitchell International Airport to Orlando
- Ave. Duration
- 2h 51m
- When
- Tuesday, Thursday, and Sunday
- Estimated price
- $170–600
- Website
- delta.com
Flights from General Mitchell International Airport to Orlando via Atlanta
- Ave. Duration
- 4h 23m
- When
- Every day
- Estimated price
- $130–650
- Phone
- +1 855-724-5411
- [email protected]
- Website
- SunRail
Train from Sand Lake Road to Sanford
- Ave. Duration
- 59 min
- Frequency
- Hourly
- Estimated price
- $3–5
- Website
- SunRail
Train from Sand Lake Road to Sanford
- Ave. Duration
- 59 min
- Frequency
- Hourly
- Estimated price
- $3–5
- Website
- SunRail
Train from Sand Lake Road to Sanford
- Ave. Duration
- 59 min
- Frequency
- Hourly
- Estimated price
- $3–5
- Website
- SunRail
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to Deland
- Ave. Duration
- 37h 13m
- Frequency
- Once daily
- Estimated price
- $500–1,100
- Website
- Amtrak
Train from Chicago Union Station to Milwaukee
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $27–60
- Website
- Amtrak
- Phone
- +1 219-926-5744
- Website
- mysouthshoreline.com
Train from Van Buren St. to South Bend Airport
- Ave. Duration
- 2h 4m
- Frequency
- Hourly
- Estimated price
- $13–15
- Schedules at
- mysouthshoreline.com
- Adults 14-64
- $13–15
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Chicago Bus Station to Washington Union Station
- Ave. Duration
- 16h 35m
- Frequency
- 4 times a day
- Estimated price
- $100–210
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Washington Union Station to Deltona
- Ave. Duration
- 16h 15m
- Frequency
- Once daily
- Estimated price
- $130–220
- Schedules at
- Flixbus USA
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More Questions & Answers
Chicago to Sanford bus services, operated by Greyhound USA, arrive at Washington Union Station.
Sanford is 1h ahead of Chicago. It is currently 8:18 AM in Chicago and 9:18 AM in Sanford.
Chicago to Sanford train services, operated by Amtrak, arrive at Deland station.
Yes, the driving distance between Chicago to Sanford is 1108 miles. It takes approximately 20h 4m to drive from Chicago to Sanford.
There are 107+ hotels available in Sanford.






