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How to get fromChicago to Sanfordby plane, bus, bus (Amtrak, Greyhound), train, taxi, or car

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There are 8 ways to get from Chicago to Sanford by plane, bus, bus (Amtrak, Greyhound), train, taxi, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Piedmont Triad International Airport, bus

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Piedmont Triad International Airport (GSO)plane plane ORD - GSO
    2. Take the bus from High Point Terminal to Sanfordbus bus
    7h 48m
    $132–649

  2. Bus

    1. Take the bus from Chicago Union Station to Toledobus bus
    2. Take the bus from Toledo Bus Stop to Winston Salem(Trans Center)bus bus
    3. Take the bus from Winston-Salem to Sanfordbus bus
    21h 35m
    $180–313

  3. Train, taxi (Amtrak)

    1. Take the train from Chicago Union Station to Southern Pines Stationtrain train Floridian
    2. Take the taxi from Southern Pines Station to Sanfordtaxi taxi
    26h 19m
    $433–836

  4. Drive 754.3 mi

    1. Drive from Chicago to Sanfordcar car 754.3 mi
    14h 8m
    $138–199

  5. Fly Chicago Midway International Airport to Raleigh-Durham International Airport, bus

    1. Fly from Chicago Midway International Airport (MDW) to Raleigh-Durham International Airport (RDU)plane plane MDW - RDU
    2. Take the bus from Raleigh Bus Station to Sanfordbus bus
    9h 1m
    $172–339

  6. Fly Chicago O'Hare International Airport to Raleigh-Durham International Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Raleigh-Durham International Airport (RDU)plane plane ORD - RDU
    2. Take the bus from Raleigh Bus Station to Sanfordbus bus
    9h 25m
    $192–789

  7. Fly Chicago O'Hare International Airport to Charlotte Douglas International Airport, train, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Charlotte Douglas International Airport (CLT)plane plane ORD - CLT
    2. Take the train from Charlotte Amtrak Station to High Pointtrain train
    3. Take the bus from High Point Terminal to Sanfordbus bus
    9h 56m
    $162–497

  8. Fly Chicago Midway International Airport to Charlotte Douglas International Airport, train, bus

    1. Fly from Chicago Midway International Airport (MDW) to Charlotte Douglas International Airport (CLT)plane plane MDW - CLT
    2. Take the train from Charlotte Amtrak Station to High Pointtrain train
    3. Take the bus from High Point Terminal to Sanfordbus bus
    9h 39m
    $152–737

Chicago to Sanford by bus

Calendar2Weekly Buses
Duration21h 35mAverage Duration
Ticket$180Cheapest Price
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Questions & Answers

Map of how to get from Chicago to Sanford.ExpandLaunch map view
  • Distance: 697.1 mi
  • Duration: 7h 48m

What companies run services between Chicago, IL, USA and Sanford, NC, USA?

You can take a bus from Chicago Union Station to Sanford via Toledo Bus Stop and Winston-Salem in around 21h 35m.

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