Rome2Rio

How to get fromChicago to Sanibelby plane, bus (Greyhound, Flixbus), train, bus, or car

Find Transport to Sanibel

See all options

There are 5 ways to get from Chicago to Sanibel by plane, bus (Greyhound, Flixbus), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Chicago Midway International Airport

    best
    1. Fly from Chicago Midway International Airport (MDW) to Ft. Myers (RSW)plane plane MDW - RSW
    4h 51m
    $208–750

  2. Fly from Chicago O'Hare International Airport

    cheapest
    1. Fly from Chicago O'Hare International Airport (ORD) to Ft. Myers (RSW)plane plane ORD - RSW
    5h 15m
    $178–590

  3. Bus

    1. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Orlando Bus Stationbus bus
    3. Take the bus from Orlando Bus Station to Fort Myers Bus Stopbus bus
    32h 21m
    $252–455

  4. Train, bus

    1. Take the train from Chicago Union Station to Tampatrain train Floridian
    2. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus FlixBus 2421
    44h 56m
    $677–1,284

  5. Drive 1,242.9 mi

    1. Drive from Chicago to Sanibelcar car 1,242.9 mi
    22h 53m
    $227–328

Chicago Midway International Airport (MDW) to Ft. Myers (RSW) flights

Calendar51Weekly Planes
Duration3h 58mAverage Duration
Ticket$136Cheapest Price
See schedules

Questions & Answers

Map of how to get from Chicago to Sanibel.ExpandLaunch map view
  • Distance: 1,143.6 mi
  • Duration: 4h 51m

What companies run services between Chicago, IL, USA and Sanibel, FL, USA?

Southwest Airlines and Delta fly from Chicago Midway International Airport (MDW) to Ft. Myers (RSW) every 4 hours. Alternatively, you can take a bus from Chicago Bus Station to Sanibel via Atlanta Bus Station, Orlando Bus Station, Rosa Parks Transportation Ctr, and Cape Coral Transfer Center in around 32h 21m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers