Rome2Rio

How to get fromChicago to Sanibel Islandby plane, bus (Greyhound, Flixbus), train, bus, or car

Find Transport to Sanibel Island

See all options

There are 5 ways to get from Chicago to Sanibel Island by plane, bus (Greyhound, Flixbus), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Chicago Midway International Airport

    best
    1. Fly from Chicago Midway International Airport (MDW) to Ft. Myers (RSW)plane plane MDW - RSW
    4h 49m
    $218–745

  2. Fly from Chicago O'Hare International Airport

    cheapest
    1. Fly from Chicago O'Hare International Airport (ORD) to Ft. Myers (RSW)plane plane ORD - RSW
    5h 13m
    $188–585

  3. Bus

    1. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to University of South Floridabus bus
    3. Take the bus from Tampa USF to Fort Myersbus bus
    26h 59m
    $285–492

  4. Train, bus

    1. Take the train from Chicago Union Station to Tampatrain train Floridian
    2. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus FlixBus 2421
    45h 4m
    $666–1,284

  5. Drive 1,241.9 mi

    1. Drive from Chicago to Sanibel Islandcar car 1,241.9 mi
    22h 51m
    $227–328

Chicago Midway International Airport (MDW) to Ft. Myers (RSW) flights

Calendar51Weekly Planes
Duration3h 58mAverage Duration
Ticket$140Cheapest Price
See schedules

Questions & Answers

Map of how to get from Chicago to Sanibel Island.ExpandLaunch map view
  • Distance: 1,142.6 mi
  • Duration: 4h 49m

What companies run services between Chicago, IL, USA and Sanibel Island, FL, USA?

Southwest Airlines and Delta fly from Chicago Midway International Airport (MDW) to Ft. Myers (RSW) every 4 hours. Alternatively, you can take a bus from Chicago Bus Station to Sanibel Island via Atlanta Bus Station, Tampa USF, and Fort Myers in around 26h 59m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers