There are 6 ways to get from Chicago to Southern Illinois University Carbondale by plane, train (Amtrak), bus (Flixbus, Amtrak), car, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Williamson County Regional Airport
best- Fly from Chicago O'Hare International Airport (ORD) to Williamson County Regional Airport (MWA)plane ORD - MWA
3h 27m$118–260Fly to Barkley Regional Airport, drive
cheapest- Fly from Chicago O'Hare International Airport (ORD) to Barkley Regional Airport (PAH)plane ORD - PAH
- Drive from Barkley Regional Airport (PAH) to Southern Illinois University Carbondalecar
4h 43m$58–323Train (Amtrak)
- Take the train from Chicago Union Station to Carbondaletrain Saluki / ...
5h 51m$95–210Bus
- Take the bus from Chicago Bus Station to St Louis Bus Stationbus FlixBus 2510 / ...
- Take the bus from St. Louis to Carbondalebus Amtrak Thruway Connecting Service
9h 16m$65–126Drive 331.6 mi
- Drive from Chicago to Southern Illinois University Carbondalecar 331.6 mi
5h 34m$61–88Fly to Cape Girardeau Municipal Airport, taxi
- Fly from Chicago O'Hare International Airport (ORD) to Cape Girardeau Municipal Airport (CGI)plane ORD - CGI
- Take the taxi from Cape Girardeau Municipal Airport (CGI) to Southern Illinois University Carbondaletaxi
4h 35m$208–375
Chicago O'Hare International Airport (ORD) to Williamson County Regional Airport (MWA) flights
Questions & Answers
The cheapest way to get from Chicago to Southern Illinois University Carbondale is to drive which costs $60 - $90 and takes 5h 34m.
The fastest way to get from Chicago to Southern Illinois University Carbondale is to fly which takes 3h 27m and costs $110 - $260.
No, there is no direct bus from Chicago station to Southern Illinois University Carbondale. However, there are services departing from Chicago Bus Station and arriving at Carbondale via St. Louis. The journey, including transfers, takes approximately 9h 16m.
Yes, there is a direct train departing from Chicago Union Station station and arriving at Carbondale. Services depart three times a day, and operate every day. The journey takes approximately 5h 30m.
The distance between Chicago and Southern Illinois University Carbondale is 331 miles. The road distance is 333.5 miles.
The best way to get from Chicago to Southern Illinois University Carbondale without a car is to train which takes 5h 51m and costs $95 - $210.
It takes approximately 3h 27m to get from Chicago to Southern Illinois University Carbondale, including transfers.
Chicago to Southern Illinois University Carbondale bus services, operated by Flixbus USA, depart from Chicago Bus Station.
Chicago to Southern Illinois University Carbondale train services, operated by Amtrak, depart from Chicago Union Station.
The best way to get from Chicago to Southern Illinois University Carbondale is to fly which takes 3h 27m and costs $110 - $260. Alternatively, you can train, which costs $95 - $210 and takes 5h 51m, you could also bus, which costs $60 - $130 and takes 9h 16m.
What companies run services between Chicago, IL, USA and Southern Illinois University Carbondale, IL, USA?
Corporate Flight Management Inc and American Airlines fly from Chicago O'Hare International Airport (ORD) to Williamson County Regional Airport (MWA) 3 times a day. Alternatively, Amtrak operates a train from Chicago Union Station to Carbondale 3 times a day. Tickets cost $95–210 and the journey takes 5h 30m.
- Website
- contouraviation.com
Flights from Chicago O'Hare International Airport to Williamson County Regional Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $80–210
Flights from Chicago O'Hare International Airport to Cape Girardeau Municipal Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- $95–220
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Williamson County Regional Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- $45–300
- Website
- united.com
Flights from Chicago O'Hare International Airport to Barkley Regional Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $45–300
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to Carbondale
- Ave. Duration
- 5h 30m
- Frequency
- 3 times a day
- Estimated price
- $95–210
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Chicago Bus Station to St Louis Bus Station
- Ave. Duration
- 5h 55m
- Frequency
- Twice daily
- Estimated price
- $45–85
- Schedules at
- Flixbus USA
Bus from St. Louis to Carbondale
- Ave. Duration
- 1h 50m
- Frequency
- 5 times a week
- Estimated price
- $15–25
- Schedules at
- Flixbus USA
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from St. Louis to Carbondale
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $30–45
- Website
- Amtrak
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Chicago to Southern Illinois University Carbondale bus services, operated by Flixbus USA, arrive at St Louis Bus Station.
Chicago to Southern Illinois University Carbondale train services, operated by Amtrak, arrive at Carbondale station.
Yes, the driving distance between Chicago to Southern Illinois University Carbondale is 334 miles. It takes approximately 5h 34m to drive from Chicago to Southern Illinois University Carbondale.
There are 53+ hotels available in Southern Illinois University Carbondale.