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How to get fromChicago to Spartanburgby plane, bus (Greyhound, Flixbus), train (Amtrak), or car

Find Transport to Spartanburg

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There are 7 ways to get from Chicago to Spartanburg by plane, bus (Greyhound, Flixbus), train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Greenville–Spartanburg International Airport

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Greenville–Spartanburg International Airport (GSP)plane plane ORD - GSP
    4h 11m
    $138–555

  2. Fly Chicago O'Hare International Airport to Asheville Regional Airport, drive

    cheapest
    1. Fly from Chicago O'Hare International Airport (ORD) to Asheville Regional Airport (AVL)plane plane ORD - AVL
    2. Drive from Asheville-Airport-AVL to Spartanburgcar car
    4h 39m
    $62–330

  3. Bus

    1. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus Greyhound US0100
    2. Take the bus from Atlanta Bus Station to Spartanburgbus bus Greyhound US0670
    20h 10m
    $148–243

  4. Train (Amtrak)

    1. Take the train from Chicago Union Station to Carytrain train
    2. Take the train from Cary to Charlotte Amtrak Stationtrain train
    3. Take the train from Charlotte Amtrak Station to Spartanburg Stationtrain train
    30h 50m
    $726–1,119

  5. Drive  672.3 mi

    1. Drive from Chicago to Spartanburgcar car 672.3 mi
    12h 45m
    $123–178

  6. Fly Chicago Midway International Airport to Greenville–Spartanburg International Airport

    1. Fly from Chicago Midway International Airport (MDW) to Greenville–Spartanburg International Airport (GSP)plane plane MDW - GSP
    5h 26m
    $178–825

  7. Bus via Sandy Springs

    1. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus Greyhound US0100
    2. Take the bus from Atlanta to Servicios Zapata - Spartanburgbus bus Charlotte
    22h 4m
    $156–259

Chicago to Spartanburg by train (Amtrak)

Calendar7Weekly Trains
Duration30h 50mAverage Duration
Ticket$726Cheapest Price
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Comparing Your Travel Options

Map of how to get from Chicago to Spartanburg.ExpandLaunch map view
  • Distance: 615 mi
  • Duration: 4h 11m

What companies run services between Chicago, IL, USA and Spartanburg, SC, USA?

American Airlines, United Airlines, and Delta fly from Chicago O'Hare International Airport (ORD) to Greenville–Spartanburg International Airport (GSP) every 3 hours. Alternatively, you can take a bus from Chicago Bus Station to Spartanburg via Atlanta Bus Station and Spartanburg in around 20h 10m.

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Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

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