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How to get fromChicago to St. Louis Union Stationby train (Amtrak), bus (Flixbus), car, plane, subway, or train

Find Transport to St. Louis Union Station

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There are 6 ways to get from Chicago to St. Louis Union Station by train (Amtrak), bus (Flixbus), car, plane, subway, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    4h 54m
    $90–190

  2. Bus

    cheapest
    1. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus FlixBus 2510 / ...
    6h 2m
    $50–85

  3. Drive 296.8 mi

    1. Drive from Chicago to St. Louis Union Stationcar car 296.8 mi
    5h
    $55–79

  4. Fly from Chicago O'Hare International Airport

    1. Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane plane ORD - STL
    3h 42m
    $276–708

  5. Subway to Chicago Midway International Airport, fly

    1. Take the subway from Adams/Wabash to Midwaysubway subway
    2. Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane plane MDW - STL
    3h 26m
    $86–558

  6. Train to General Mitchell International Airport, fly

    1. Take the train from Chicago Union Station to Milwaukeetrain train
    2. Fly from General Mitchell International Airport (MKE) to Lambert–St. Louis International Airport (STL)plane plane MKE - STL
    4h 58m
    $513–921

Chicago to St. Louis Union Station by train and foot (Amtrak)

Calendar38Weekly Services
Duration4h 54mAverage Duration
Ticket$90Cheapest Price
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Questions & Answers

Map of how to get from Chicago to St. Louis Union Station.ExpandLaunch map view
  • Distance: 281.1 mi
  • Duration: 4h 54m

What companies run services between Chicago, IL, USA and St. Louis Union Station, MO, USA?

Amtrak operates a train from Chicago Union Station to St. Louis 5 times a day. Tickets cost $90–190 and the journey takes 4h 46m. Alternatively, FlixBus-us operates a bus from Chicago Bus Station to St Louis Bus Station 3 times a day, and the journey takes 5h 55m. Flixbus USA also services this route twice daily.

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