There are 4 ways to get from Chicago to Syracuse by plane, bus, ferry, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Chicago O'Hare International Airport to Catania–Fontanarossa Airport, bus
best- Fly from Chicago O'Hare International Airport (ORD) to Catania–Fontanarossa Airport (CTA)plane ORD - CTA
- Take the bus from Catania Airport to Siracusa - v.le Scala Grecabus
15h 32m€494–912Fly Chicago O'Hare International Airport to Palermo Airport, train, bus
cheapest- Fly from Chicago O'Hare International Airport (ORD) to Palermo Airport (PMO)plane ORD - PMO
- Take the train from Palermo Centrale to Catania Aeroporto Fontanarossatrain
- Take the bus from Catania Airport to Siracusa - v.le Scala Grecabus
20h 41m€266–759Fly Chicago O'Hare International Airport to Reggio Calabria Airport, ferry, train, bus
- Fly from Chicago O'Hare International Airport (ORD) to Reggio Calabria Airport (REG)plane ORD - REG
- Take the ferry from Villa S.Giovanni to Messina Marittimaferry
- Take the train from Messina Centrale to Catania Centraletrain
- Take the bus from Catania Via Archimede to Siracusa - v.le Scala Grecabus
22h 58mFly Chicago Midway International Airport to Catania–Fontanarossa Airport, bus
- Fly from Chicago Midway International Airport (MDW) to Catania–Fontanarossa Airport (CTA)plane MDW - CTA
- Take the bus from Catania Airport to Siracusa - v.le Scala Grecabus
17h 36m€334–962
Chicago O'Hare International Airport (ORD) to Catania–Fontanarossa Airport (CTA) flights
Comparing Your Travel Options
The cheapest way to get from Chicago to Syracuse is to fly and train and bus which costs €260 - €800 and takes 20h 41m.
The fastest way to get from Chicago to Syracuse is to fly and bus which takes 15h 32m and costs €490 - €950.
The distance between Chicago and Syracuse is 8323 km.
It takes approximately 15h 32m to get from Chicago to Syracuse, including transfers.
Syracuse is 7h ahead of Chicago. It is currently 8:20 PM in Chicago and 3:20 AM in Syracuse.
There are 3047+ hotels available in Syracuse.
What companies run services between Chicago, IL, USA and Syracuse, Italy?
There is no direct connection from Chicago to Syracuse. However, you can take the subway to O'Hare, walk to Chicago O'Hare International Airport (ORD) airport, fly to Catania–Fontanarossa Airport (CTA), walk to Catania Airport, then take the bus to Siracusa - v.le Scala Greca. Alternatively, you can take the subway to O'Hare, walk to Chicago O'Hare International Airport (ORD) airport, fly to Reggio Calabria Airport (REG), walk to Ravagnese - Aeroporto, take the line 118 bus to Reggio di Calabria - Piazza Garibaldi, walk to Reggio Calabria C.Le, take the train to Villa S.Giovanni, walk to Villa S.Giovanni, take the ferry to Messina Marittima, walk to Messina Centrale, take the train to Catania Centrale, walk to Catania Via Archimede, then take the bus to Siracusa - v.le Scala Greca.
- Website
- lufthansa.com
Flights from Chicago O'Hare International Airport to Catania–Fontanarossa Airport via Frankfurt
- Ave. Duration
- 12h 15m
- When
- Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €220–800
Flights from Chicago O'Hare International Airport to Catania–Fontanarossa Airport via Munich
- Ave. Duration
- 12h 30m
- When
- Monday and Sunday
- Estimated price
- €220–800
Flights from Chicago O'Hare International Airport to Reggio Calabria Airport via Rome
- Ave. Duration
- 15h 7m
- When
- Every day
- Estimated price
- €310–1,100
Flights from Chicago O'Hare International Airport to Palermo Airport via Frankfurt
- Ave. Duration
- 12h 10m
- When
- Wednesday to Friday
- Estimated price
- €210–750
Flights from Chicago O'Hare International Airport to Palermo Airport via Munich
- Ave. Duration
- 12h 32m
- When
- Monday, Friday, Sunday, and Thursday
- Estimated price
- €230–850
Flights from Chicago Midway International Airport to Catania–Fontanarossa Airport via Boston, Munich
- Ave. Duration
- 19h 5m
- When
- Friday and Saturday
- Estimated price
- €330–1,200
- Website
- ita-airways.com
Flights from Chicago O'Hare International Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 11h 30m
- When
- Friday and Sunday
- Estimated price
- €220–650
Flights from Chicago O'Hare International Airport to Reggio Calabria Airport via Rome
- Ave. Duration
- 15h 32m
- When
- Every day
- Estimated price
- €310–1,100
Flights from Chicago O'Hare International Airport to Palermo Airport via Rome
- Ave. Duration
- 12h 15m
- When
- Friday and Sunday
- Estimated price
- €230–700
Flights from Chicago Midway International Airport to Catania–Fontanarossa Airport via Boston, Rome
- Ave. Duration
- 13h 45m
- When
- Thursday and Friday
- Estimated price
- €330–950
- Website
- ryanair.com
Flights from Chicago O'Hare International Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 11h 35m
- When
- Thursday and Friday
- Estimated price
- €190–700
Flights from Chicago O'Hare International Airport to Reggio Calabria Airport via Milan Malpensa
- Ave. Duration
- 17h 17m
- When
- Monday, Wednesday, Thursday, Friday, Sunday, and Saturday
- Estimated price
- €310–1,100
Flights from Chicago O'Hare International Airport to Reggio Calabria Airport via Barcelona
- Ave. Duration
- 17h 10m
- When
- Thursday and Saturday
- Estimated price
- €310–1,100
Flights from Chicago Midway International Airport to Catania–Fontanarossa Airport via Philadelphia, Rome
- Ave. Duration
- 13h 50m
- When
- Monday
- Estimated price
- €300–1,100
- Website
- brusselsairlines.com
Flights from Chicago O'Hare International Airport to Catania–Fontanarossa Airport via Brussels
- Ave. Duration
- 13h 50m
- When
- Monday and Friday
- Estimated price
- €190–700
Flights from Chicago O'Hare International Airport to Reggio Calabria Airport via Rome
- Ave. Duration
- 15h 7m
- When
- Every day
- Estimated price
- €310–1,100
- Website
- easyjet.com
Flights from Chicago O'Hare International Airport to Catania–Fontanarossa Airport via Milan Malpensa
- Ave. Duration
- 11h 30m
- When
- Wednesday
- Estimated price
- €190–700
Flights from Chicago Midway International Airport to Catania–Fontanarossa Airport via Philadelphia, Naples
- Ave. Duration
- 14h 40m
- When
- Monday
- Estimated price
- €300–1,100
- Website
- united.com
Flights from Chicago O'Hare International Airport to Reggio Calabria Airport via Rome
- Ave. Duration
- 15h 7m
- When
- Every day
- Estimated price
- €310–1,100
- Website
- airfrance.com
Flights from Chicago O'Hare International Airport to Reggio Calabria Airport via Rome
- Ave. Duration
- 14h 40m
- When
- Every day
- Estimated price
- €310–1,100
Flights from Chicago O'Hare International Airport to Palermo Airport via Paris Charles de Gaulle
- Ave. Duration
- 14h 25m
- When
- Friday
- Estimated price
- €200–750
- Website
- swiss.com
Flights from Chicago O'Hare International Airport to Palermo Airport via Zurich
- Ave. Duration
- 11h 35m
- When
- Wednesday
- Estimated price
- €220–700
- Website
- aerlingus.com
Flights from Chicago Midway International Airport to Catania–Fontanarossa Airport via Hartford, Dublin
- Ave. Duration
- 16h 20m
- When
- Tuesday
- Estimated price
- €330–1,400
- Website
- vueling.com
Flights from Chicago Midway International Airport to Catania–Fontanarossa Airport via Boston, Barcelona
- Ave. Duration
- 14h 55m
- When
- Friday
- Estimated price
- €290–1,100
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Messina Centrale to Catania Centrale
- Ave. Duration
- 1h 48m
- Frequency
- Every 30 minutes
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Palermo Centrale to Catania Aeroporto Fontanarossa
- Ave. Duration
- 2h 47m
- Frequency
- Every 3 hours
- Estimated price
- €28–40
- Website
- Trenitalia
- Phone
- +39 0935 22 460
- Website
- interbus.it
Bus from Catania Airport to Siracusa - v.le Scala Greca
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
Bus from Catania Via Archimede to Siracusa - v.le Scala Greca
- Ave. Duration
- 1h 5m
- Frequency
- Hourly
- Estimated price
- €2–9
- Schedules at
- interbus.it
Bus from Catania Airport to Siracusa - v.le Scala Greca
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
Bus from Catania Airport to Siracusa - v.le Scala Greca
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
- Phone
- +39.06.5210550
- Website
- Trenitalia
Ferry from Villa S.Giovanni to Messina Marittima
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- Trenitalia
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
Travelling by boat in Italy
Read the travel guide





