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How to get fromChicago to Syracuse Universityby plane, train (Amtrak), bus (Greyhound), car, train, or bus

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There are 8 ways to get from Chicago to Syracuse University by plane, train (Amtrak), bus (Greyhound), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Syracuse Hancock International Airport

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Syracuse Hancock International Airport (SYR)plane plane ORD - SYR
    5h 46m
    $124–663

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from Chicago Bus Station to Cleveland Bus Stationbus bus Greyhound US0164
    2. Take the bus from Cleveland Bus Station to Syracuse Bus Stationbus bus Greyhound US0171
    16h 4m
    $112–221

  3. Train (Amtrak)

    1. Take the train from Chicago Union Station to Syracuse Regional Transportation Centertrain train Lake Shore Limited
    14h 2m
    $220–446

  4. Drive 677.1 mi

    1. Drive from Chicago to Syracuse Universitycar car 677.1 mi
    11h 34m
    $124–179

  5. Fly Chicago Midway International Airport to Syracuse Hancock International Airport

    1. Fly from Chicago Midway International Airport (MDW) to Syracuse Hancock International Airport (SYR)plane plane MDW - SYR
    7h 5m
    $154–863

  6. Fly Chicago Midway International Airport to Rochester, train

    1. Fly from Chicago Midway International Airport (MDW) to Rochester (ROC)plane plane MDW - ROC
    2. Take the train from Rochester to Syracuse Regional Transportation Centertrain train
    6h 38m
    $172–945

  7. Fly Chicago O'Hare International Airport to Rochester, train

    1. Fly from Chicago O'Hare International Airport (ORD) to Rochester (ROC)plane plane ORD - ROC
    2. Take the train from Rochester to Syracuse Regional Transportation Centertrain train
    7h 3m
    $142–795

  8. Fly Chicago Midway International Airport to Buffalo Niagara International Airport, bus

    1. Fly from Chicago Midway International Airport (MDW) to Buffalo Niagara International Airport (BUF)plane plane MDW - BUF
    2. Take the bus from Buffalo Niagara International Airport to Syracuse Bus Stationbus bus
    7h 43m
    $130–533

Chicago O'Hare International Airport (ORD) to Syracuse Hancock International Airport (SYR) flights

Calendar110Weekly Planes
Duration3h 26mAverage Duration
Ticket$122Cheapest Price
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Questions & Answers

Map of how to get from Chicago to Syracuse University.ExpandLaunch map view
  • Distance: 636.4 mi
  • Duration: 5h 46m

What companies run services between Chicago, IL, USA and Syracuse University, NY, USA?

American Airlines, United Airlines, and Delta fly from Chicago O'Hare International Airport (ORD) to Syracuse Hancock International Airport (SYR) hourly. Alternatively, Amtrak operates a train from Chicago Union Station to Syracuse Regional Transportation Center twice daily. Tickets cost $210–440 and the journey takes 12h 58m.

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