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How to get fromChicago to Tyroneby plane, bus, train (Amtrak), bus (Flixbus, Greyhound), car, train, or bus (Greyhound, Flixbus)

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There are 9 ways to get from Chicago to Tyrone by plane, bus, train (Amtrak), bus (Flixbus, Greyhound), car, train, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Penn State University Park Airport, bus

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Penn State University Park Airport (SCE)plane plane ORD - SCE
    2. Take the bus from State College Bus Station to Tyrone Bus Stopbus bus
    6h 28m
    $68–357

  2. Train (Amtrak)

    1. Take the train from Chicago Union Station to Pittsburgh Amtrak Stationtrain train Floridian
    2. Take the train from Pittsburgh Amtrak Station to Tyrone Stationtrain train Pennsylvanian
    13h 14m
    $195–400

  3. Bus

    1. Take the bus from Chicago Bus Station to State College Regional Airportbus bus FlixBus N2641 / ...
    2. Take the bus from State College Bus Station to Tyrone Bus Stopbus bus Greyhound US0400s
    15h 14m
    $106–177

  4. Drive 561.2 mi

    1. Drive from Chicago to Tyronecar car 561.2 mi
    9h 22m
    $103–148

  5. Fly Chicago O'Hare International Airport to Johnstown-Cambria County Airport, train

    1. Fly from Chicago O'Hare International Airport (ORD) to Johnstown-Cambria County Airport (JST)plane plane ORD - JST
    2. Take the train from Johnstown Amtrak Station to Tyrone Stationtrain train
    6h 4m
    $88–388

  6. Fly Chicago O'Hare International Airport to Harrisburg International Airport, train

    1. Fly from Chicago O'Hare International Airport (ORD) to Harrisburg International Airport (MDT)plane plane ORD - MDT
    2. Take the train from Harrisburg to Tyrone Stationtrain train
    7h 48m
    $104–447

  7. Fly Chicago Midway International Airport to Pittsburgh International Airport, train

    1. Fly from Chicago Midway International Airport (MDW) to Pittsburgh International Airport (PIT)plane plane MDW - PIT
    2. Take the train from Pittsburgh Amtrak Station to Tyrone Stationtrain train
    8h 18m
    $118–550

  8. Fly Chicago O'Hare International Airport to Pittsburgh International Airport, train

    1. Fly from Chicago O'Hare International Airport (ORD) to Pittsburgh International Airport (PIT)plane plane ORD - PIT
    2. Take the train from Pittsburgh Amtrak Station to Tyrone Stationtrain train
    8h 44m
    $422–1,290

  9. Bus via Pittsburgh

    1. Take the bus from Chicago Bus Station to Pittsburgh Intermodal Stationbus bus Greyhound US0164
    2. Take the bus from Pittsburgh Intermodal Station to Tyrone Bus Stopbus bus Greyhound US0400s
    15h 25m
    $93–179

Chicago to Tyrone by train (Amtrak)

Calendar7Weekly Trains
Duration13h 14mAverage Duration
Ticket$195Cheapest Price
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Questions & Answers

Map of how to get from Chicago to Tyrone.ExpandLaunch map view
  • Distance: 576.4 mi
  • Duration: 6h 28m

What companies run services between Chicago, IL, USA and Tyrone, PA, USA?

You can take a train from Chicago Union Station to Tyrone Station via Pittsburgh Amtrak Station in around 13h 14m. Alternatively, you can take a bus from Chicago Bus Station to Tyrone Bus Stop via State College, State College, and State College Bus Station in around 15h 14m.

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