Rome2Rio

How to get fromChicago to Waterlooby train (Amtrak), bus (Flixbus), car, plane, or train

Find Transport to Waterloo

See all options

There are 7 ways to get from Chicago to Waterloo by train (Amtrak), bus (Flixbus), car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    5h 20m
    $148–255

  2. Drive 315 mi

    cheapest
    1. Drive from Chicago to Waterloocar car 315 mi
    5h 21m
    $58–83

  3. Bus (Flixbus)

    1. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus FlixBus 2510 / ...
    6h 29m
    $105–151

  4. Fly Chicago O'Hare International Airport to Lambert–St. Louis International Airport, train

    1. Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane plane ORD - STL
    2. Take the train from LAMBERT AIRPORT TERMINAL #1 station to MEMORIAL HOSPITAL stationtrain train
    4h 46m
    $326–768

  5. Fly Chicago Midway International Airport to Lambert–St. Louis International Airport, train

    1. Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane plane MDW - STL
    2. Take the train from LAMBERT AIRPORT TERMINAL #1 station to MEMORIAL HOSPITAL stationtrain train
    4h 30m
    $136–618

  6. Train to General Mitchell International Airport, fly to Lambert–St. Louis International Airport, train

    1. Take the train from Chicago Union Station to Milwaukeetrain train
    2. Fly from General Mitchell International Airport (MKE) to Lambert–St. Louis International Airport (STL)plane plane MKE - STL
    3. Take the train from LAMBERT AIRPORT TERMINAL #1 station to MEMORIAL HOSPITAL stationtrain train
    6h 4m
    $563–983

  7. Fly Chicago O'Hare International Airport to Abraham Lincoln Capital Airport, train

    1. Fly from Chicago O'Hare International Airport (ORD) to Abraham Lincoln Capital Airport (SPI)plane plane ORD - SPI
    2. Take the train from Springfield to St. Louistrain train
    6h 23m
    $140–466

Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL) flights

Calendar123Weekly Planes
Duration1h 28mAverage Duration
Ticket$65Cheapest Price
See schedules

Questions & Answers

Map of how to get from Chicago to Waterloo.ExpandLaunch map view
  • Distance: 304.9 mi
  • Duration: 5h 20m

What companies run services between Chicago, IL, USA and Waterloo, IL, USA?

Amtrak operates a train from Chicago Union Station to St. Louis 5 times a day. Tickets cost $90–190 and the journey takes 4h 46m. Alternatively, Flixbus USA operates a bus from Chicago Bus Station to St Louis Bus Station twice daily. Tickets cost $50–85 and the journey takes 5h 55m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

More Questions & Answers