Rome2Rio

How to get fromChicago to Wilkesboroby plane, shuttle, bus, bus (Amtrak, Greyhound), train, or car

Find Transport to Wilkesboro

See all options

There are 10 ways to get from Chicago to Wilkesboro by plane, shuttle, bus, bus (Amtrak, Greyhound), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Tri-Cities Regional Tn/Va Airport, shuttle, bus

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Tri-Cities Regional Tn/Va Airport (TRI)plane plane ORD - TRI
    2. Take a shuttle bus from Black Bear Resort to Booneshuttle bus
    3. Take the bus from Boone to Wilkesborobus bus
    8h 34m

  2. Drive 654.1 mi

    cheapest
    1. Drive from Chicago to Wilkesborocar car 654.1 mi
    12h 52m
    $120–173

  3. Bus

    1. Take the bus from Chicago Union Station to Toledobus bus
    2. Take the bus from Toledo Bus Stop to Winston Salem(Trans Center)bus bus
    3. Take the bus from Forsyth Hospital to Wilkesborobus bus
    20h 53m

  4. Train, bus

    1. Take the train from Chicago Union Station to Carytrain train
    2. Take the train from Cary to High Pointtrain train
    3. Take the bus from Forsyth Hospital to Wilkesborobus bus
    31h 3m

  5. Fly Chicago O'Hare International Airport to Piedmont Triad International Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Piedmont Triad International Airport (GSO)plane plane ORD - GSO
    2. Take the bus from Forsyth Hospital to Wilkesborobus bus
    8h 7m

  6. Fly Chicago O'Hare International Airport to Charlotte Douglas International Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Charlotte Douglas International Airport (CLT)plane plane ORD - CLT
    2. Take the bus from Charlotte to Winston Salembus bus
    3. Take the bus from Winston-Salem to Wilkesborobus bus
    9h 10m

  7. Fly Chicago O'Hare International Airport to Asheville Regional Airport, shuttle, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Asheville Regional Airport (AVL)plane plane ORD - AVL
    2. Take a shuttle bus from Asheville Airport to Black Bear Resortshuttle bus
    3. Take a shuttle bus from Black Bear Resort to Booneshuttle bus
    4. Take the bus from Boone to Wilkesborobus bus
    10h 12m

  8. Fly Chicago Midway International Airport to Charlotte Douglas International Airport, bus

    1. Fly from Chicago Midway International Airport (MDW) to Charlotte Douglas International Airport (CLT)plane plane MDW - CLT
    2. Take the bus from Charlotte to Winston Salembus bus
    3. Take the bus from Winston-Salem to Wilkesborobus bus
    8h 53m

  9. Fly Chicago Midway International Airport to Raleigh-Durham International Airport, train, bus

    1. Fly from Chicago Midway International Airport (MDW) to Raleigh-Durham International Airport (RDU)plane plane MDW - RDU
    2. Take the train from Durham Amtrak Station to High Pointtrain train
    3. Take the bus from Forsyth Hospital to Wilkesborobus bus
    11h 12m

  10. Bus via Columbus

    1. Take the bus from Chicago to N Wilson Rd & Ferrell Pl - Columbusbus bus
    2. Take the bus from Columbus to Charlottebus bus
    3. Take the bus from Charlotte to Winston Salembus bus
    4. Take the bus from Winston-Salem to Wilkesborobus bus
    23h 25m

Chicago O'Hare International Airport (ORD) to Tri-Cities Regional Tn/Va Airport (TRI) flights

Calendar27Weekly Planes
Duration2h 57mAverage Duration
Ticket$75Cheapest Price
See schedules

Questions & Answers

Map of how to get from Chicago to Wilkesboro.ExpandLaunch map view
  • Distance: 607.8 mi
  • Duration: 8h 34m

What companies run services between Chicago, IL, USA and Wilkesboro, NC, USA?

You can take a bus from Chicago Union Station to Wilkesboro via Toledo Bus Stop, Winston Salem(Trans Center), Winston-Salem Transportation Center, and Forsyth Hospital in around 20h 53m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers