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How to get fromChicago to Wilkesboroby plane, bus, bus (Amtrak, Greyhound), train, car, or shuttle

Find Transport to Wilkesboro

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There are 9 ways to get from Chicago to Wilkesboro by plane, bus, bus (Amtrak, Greyhound), train, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Piedmont Triad International Airport, bus

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Piedmont Triad International Airport (GSO)plane plane ORD - GSO
    2. Take the bus from Forsyth Hospital to Wilkesborobus bus
    8h 2m
    $88–363

  2. Bus

    1. Take the bus from Chicago Union Station to Toledobus bus
    2. Take the bus from Toledo Bus Stop to Winston Salem(Trans Center)bus bus
    3. Take the bus from Forsyth Hospital to Wilkesborobus bus
    21h 13m

  3. Train, bus

    1. Take the train from Chicago Union Station to Carytrain train
    2. Take the train from Cary to High Pointtrain train
    3. Take the bus from Forsyth Hospital to Wilkesborobus bus
    31h 3m
    $651–1,003

  4. Drive  654.1 mi

    1. Drive from Chicago to Wilkesborocar car 654.1 mi
    12h 52m
    $120–173

  5. Fly Chicago O'Hare International Airport to Tri-Cities Regional Tn/Va Airport, shuttle, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Tri-Cities Regional Tn/Va Airport (TRI)plane plane ORD - TRI
    2. Take a shuttle bus from Black Bear Resort to Booneshuttle bus
    3. Take the bus from Boone to Wilkesborobus bus
    8h 37m
    $212–467

  6. Fly Chicago O'Hare International Airport to Charlotte Douglas International Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Charlotte Douglas International Airport (CLT)plane plane ORD - CLT
    2. Take the bus from Charlotte to Winston Salembus bus
    3. Take the bus from Winston-Salem to Wilkesborobus bus
    9h 8m
    $144–366

  7. Fly Chicago Midway International Airport to Charlotte Douglas International Airport, bus

    1. Fly from Chicago Midway International Airport (MDW) to Charlotte Douglas International Airport (CLT)plane plane MDW - CLT
    2. Take the bus from Charlotte to Winston Salembus bus
    3. Take the bus from Winston-Salem to Wilkesborobus bus
    8h 43m
    $144–766

  8. Fly Chicago O'Hare International Airport to Asheville Regional Airport, shuttle, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Asheville Regional Airport (AVL)plane plane ORD - AVL
    2. Take a shuttle bus from Asheville Airport to Black Bear Resortshuttle bus
    3. Take a shuttle bus from Black Bear Resort to Booneshuttle bus
    4. Take the bus from Boone to Wilkesborobus bus
    10h 10m
    $312–577

  9. Bus via Columbus

    1. Take the bus from Chicago to Columbusbus bus
    2. Take the bus from Columbus to Charlottebus bus
    3. Take the bus from Charlotte to Winston Salembus bus
    4. Take the bus from Winston-Salem to Wilkesborobus bus
    23h 25m
    $94–230

Chicago to Wilkesboro by bus

Calendar7Weekly Buses
Duration23h 25mAverage Duration
Ticket$94Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Chicago to Wilkesboro.ExpandLaunch map view
  • Distance: 685.4 mi
  • Duration: 8h 2m

What companies run services between Chicago, IL, USA and Wilkesboro, NC, USA?

You can take a bus from Chicago Union Station to Wilkesboro via Toledo Bus Stop, Winston Salem(Trans Center), Winston-Salem Transportation Center, and Forsyth Hospital in around 21h 13m.

Airlines
Train operators
Bus operators

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