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How to get fromChicago to Williamsvilleby plane, train (Amtrak), bus, car, or bus (Greyhound)

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There are 6 ways to get from Chicago to Williamsville by plane, train (Amtrak), bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Chicago Midway International Airport

    best
    1. Fly from Chicago Midway International Airport (MDW) to Buffalo Niagara International Airport (BUF)plane plane MDW - BUF
    3h 6m
    $176–452

  2. Bus

    cheapest
    1. Take the bus from Chicago to Clevelandbus bus Chicago
    2. Take the bus from Cleveland, OH to Buffalo, NYbus bus Cinncinati,OH-Buffalo
    12h 40m
    $54–141

  3. Train (Amtrak)

    1. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train Lake Shore Limited
    10h 32m
    $191–364

  4. Drive 537.8 mi

    1. Drive from Chicago to Williamsvillecar car 537.8 mi
    9h 8m
    $99–142

  5. Fly from Chicago O'Hare International Airport

    1. Fly from Chicago O'Hare International Airport (ORD) to Buffalo Niagara International Airport (BUF)plane plane ORD - BUF
    3h 32m
    $166–322

  6. Bus via Brook Park (Greyhound)

    1. Take the bus from Chicago Bus Station to Cleveland Bus Stationbus bus Greyhound US0164
    2. Take the bus from Cleveland Bus Station to Buffalobus bus Greyhound US0171 / ...
    13h 50m
    $88–163

Chicago to Williamsville by bus

Calendar7Weekly Buses
Duration12h 40mAverage Duration
Ticket$54Cheapest Price
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Questions & Answers

Map of how to get from Chicago to Williamsville.ExpandLaunch map view
  • Distance: 481.1 mi
  • Duration: 3h 6m

What companies run services between Chicago, IL, USA and Williamsville, NY, USA?

Southwest Airlines and Delta fly from Chicago Midway International Airport (MDW) to Buffalo Niagara International Airport (BUF) 4 times a day. Alternatively, Amtrak operates a train from Chicago Union Station to Buffalo Depew Station twice daily. Tickets cost $170–350 and the journey takes 10h 23m.

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