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How to get fromChicago to Wilmingtonby plane, train, train (Amtrak), bus (Greyhound), car, or bus

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There are 11 ways to get from Chicago to Wilmington by plane, train, train (Amtrak), bus (Greyhound), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago Midway International Airport to Philadelphia International Airport, train

    best
    1. Fly from Chicago Midway International Airport (MDW) to Philadelphia International Airport (PHL)plane plane MDW - PHL
    2. Take the train from 30th Street Station to Wilmingtontrain train
    4h 51m
    $150–928

  2. Fly Chicago O'Hare International Airport to Lancaster, drive

    cheapest
    1. Fly from Chicago O'Hare International Airport (ORD) to Lancaster (LNS)plane plane ORD - LNS
    2. Drive from Lancaster-Airport-LNS to Wilmingtoncar car
    5h 15m
    $76–379

  3. Train via Washington (Amtrak)

    1. Take the train from Chicago Union Station to Rockville Amtraktrain train Floridian
    2. Take the train from Washington Union Station to Wilmingtontrain train Carolinian / ...
    19h
    $266–1,147

  4. Bus (Greyhound)

    1. Take the bus from Chicago Bus Station to Baltimore Downtown Bus Stationbus bus Greyhound US0164
    2. Take the bus from Baltimore Downtown Bus Station to Wilmington Bus Stationbus bus Greyhound US0305 / ...
    20h 5m
    $125–237

  5. Drive 739.5 mi

    1. Drive from Chicago to Wilmingtoncar car 739.5 mi
    12h 35m
    $135–195

  6. Fly Chicago O'Hare International Airport to Philadelphia International Airport, train

    1. Fly from Chicago O'Hare International Airport (ORD) to Philadelphia International Airport (PHL)plane plane ORD - PHL
    2. Take the train from 30th Street Station to Wilmingtontrain train
    5h 11m
    $130–778

  7. Fly Chicago Midway International Airport to Baltimore-Washington International Airport, train

    1. Fly from Chicago Midway International Airport (MDW) to Baltimore-Washington International Airport (BWI)plane plane MDW - BWI
    2. Take the train from BWI Thurgood Marshall to Wilmingtontrain train
    5h 11m
    $140–907

  8. Fly Chicago Midway International Airport to Ronald Reagan Washington National Airport, train

    1. Fly from Chicago Midway International Airport (MDW) to Ronald Reagan Washington National Airport (DCA)plane plane MDW - DCA
    2. Take the train from Washington Union Station to Wilmingtontrain train
    5h 24m
    $150–1,362

  9. Fly Chicago O'Hare International Airport to Ronald Reagan Washington National Airport, train

    1. Fly from Chicago O'Hare International Airport (ORD) to Ronald Reagan Washington National Airport (DCA)plane plane ORD - DCA
    2. Take the train from Washington Union Station to Wilmingtontrain train
    5h 45m
    $150–1,512

  10. Bus, train

    1. Take the bus from Chicago Bus Station to Allentownbus bus
    2. Take the bus from Allentown Transportation Center to Philadelphia 30th St Stationbus bus
    3. Take the train from Gray 30th St Station to Wilmingtontrain train Wil
    21h 51m
    $169–271

  11. Train (Amtrak)

    1. Take the train from Chicago Union Station to Wilmingtontrain train Cardinal
    25h 35m
    $320–700

Chicago to Wilmington by train and subway (Amtrak)

Calendar7Weekly Services
Duration19hAverage Duration
Ticket$266Cheapest Price
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Questions & Answers

Map of how to get from Chicago to Wilmington.ExpandLaunch map view
  • Distance: 710.6 mi
  • Duration: 4h 51m

What companies run services between Chicago, IL, USA and Wilmington, DE, USA?

You can take a train from Chicago Union Station to Wilmington via Rockville Amtrak, Rockville, Red Line Center Platform, Union Station, Red Line Center Platform, and Washington Union Station in around 19h. Alternatively, you can take a bus from Chicago Bus Station to Wilmington Bus Station via Baltimore Downtown Bus Station in around 20h 5m.

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