Rome2Rio

How to get fromChicago to Wythevilleby plane, car, bus, train, shuttle, or bus (Flixbus)

Find Transport to Wytheville

See all options

There are 10 ways to get from Chicago to Wytheville by plane, car, bus, train, shuttle, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Greenbrier Valley Airport, drive

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Greenbrier Valley Airport (LWB)plane plane ORD - LWB
    2. Drive from Greenbrier Valley Airport (LWB) to Wythevillecar car
    5h 45m
    $80–362

  2. Fly Chicago O'Hare International Airport to Roanoke Regional Airport-Woodrum Field, bus

    cheapest
    1. Fly from Chicago O'Hare International Airport (ORD) to Roanoke Regional Airport-Woodrum Field (ROA)plane plane ORD - ROA
    2. Take the bus from Airport to Exit 118 - Park and Ridebus bus
    3. Take the bus from Route 460 Park and Ride to Rural King Shopping Centerbus bus
    7h 27m
    $78–385

  3. Bus

    1. Take the bus from Chicago to Columbus - Mound Stbus bus Chicago
    2. Take the bus from Columbus - Mound St to Wythevillebus bus Columbus
    16h 24m
    $86–179

  4. Train, bus

    1. Take the train from Chicago Union Station to Ashland Amtrak Stationtrain train Cardinal
    2. Take the bus from Ashland to Wythevillebus bus Columbus
    17h 39m
    $194–392

  5. Drive 592.8 mi

    1. Drive from Chicago to Wythevillecar car 592.8 mi
    11h 12m
    $109–157

  6. Fly Chicago O'Hare International Airport to Yeager Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Yeager Airport (CRW)plane plane ORD - CRW
    2. Take the bus from Charleston, WV to Wythevillebus bus
    7h 27m
    $112–470

  7. Fly Chicago O'Hare International Airport to Piedmont Triad International Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Piedmont Triad International Airport (GSO)plane plane ORD - GSO
    2. Take the bus from Winston Salem(Trans Center) to Wythevillebus bus
    7h 22m
    $162–696

  8. Fly Chicago Midway International Airport to Charlotte Douglas International Airport, bus

    1. Fly from Chicago Midway International Airport (MDW) to Charlotte Douglas International Airport (CLT)plane plane MDW - CLT
    2. Take the bus from Charlotte Bus Station to Max Meadowsbus bus
    7h 33m
    $182–796

  9. Fly Chicago O'Hare International Airport to Tri-Cities Regional Tn/Va Airport, shuttle, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Tri-Cities Regional Tn/Va Airport (TRI)plane plane ORD - TRI
    2. Take a shuttle bus from Black Bear Resort to Low Gapshuttle bus
    3. Take the bus from Park and Ride Lot at I-81 Exit 5 to Rural King Shopping Centerbus bus
    9h 12m
    $292–680

  10. Bus via Columbus

    1. Take the bus from Chicago Bus Station to Columbusbus bus FlixBus 2511 / ...
    2. Take the bus from Columbus to Wythevillebus bus Bsb 32
    17h 31m

Chicago O'Hare International Airport (ORD) to Greenbrier Valley Airport (LWB) flights

Calendar7Weekly Planes
Duration1h 53mAverage Duration
Ticket$60Cheapest Price
See schedules

Questions & Answers

Map of how to get from Chicago to Wytheville.ExpandLaunch map view
  • Distance: 612.2 mi
  • Duration: 5h 45m

What companies run services between Chicago, IL, USA and Wytheville, VA, USA?

You can take a bus from Chicago to Wytheville via Columbus - Mound St and Wytheville in around 16h 24m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers