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How to get fromChile to Guayaquilby plane, bus, or car

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There are 6 ways to get from Chile to Guayaquil by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Antofagasta Airport

    best
    1. Fly from Antofagasta Airport (ANF) to José Joaquín De Olmedo International Airport (GYE)plane plane ANF - GYE
    8h 25m
    $294–578

  2. Bus #2

    cheapest
    1. Take the bus from Terminal Sur de Santiago to Gran Terminal Terrestre Plaza Nortebus bus Lima
    2. Take the bus from Gran Terminal Terrestre Plaza Norte to Terminal Terrestre de Guayaquilbus bus Lima-Cucuta / ...
    3d 12h
    $196–301

  3. Bus via Tumbes

    1. Take the bus from Terminal San Borja to Gran Terminal Terrestre Plaza Nortebus bus
    2. Take the bus from Gran Terminal Terrestre Plaza Norte to Tumbesbus bus
    3. Take the bus from Tumbes to Terminal Terrestre de Guayaquilbus bus
    2d 20h
    $253–336

  4. Drive 4,694.9 km

    1. Drive from Santiago to Guayaquilcar car 4,694.9 km
    2d 12h
    $579–837

  5. Fly from Comodoro Arturo Merino Benítez International Airport

    1. Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to José Joaquín De Olmedo International Airport (GYE)plane plane SCL - GYE
    8h 20m
    $244–554

  6. Bus

    1. Take the bus from Terminal San Borja to Gran Terminal Terrestre Plaza Nortebus bus Cúcuta
    2. Take the bus from Gran Terminal Terrestre Plaza Norte to Terminal Terrestre de Guayaquilbus bus Lima-Cucuta / ...
    3d 2h
    $311–391

Antofagasta Airport (ANF) to José Joaquín De Olmedo International Airport (GYE) flights

Calendar7Weekly Planes
Duration9h 15mAverage Duration
Ticket$278Cheapest Price
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Questions & Answers

Map of how to get from Chile to Guayaquil.ExpandLaunch map view
  • Distance: 2,603.4 km
  • Duration: 8h 25m

What companies run services between Chile and Guayaquil, Ecuador?

LATAM Chile and Sky Airline fly from Antofagasta Airport (ANF) to José Joaquín De Olmedo International Airport (GYE) once daily. Alternatively, you can take a subway from La Moneda Dirección San Pablo to Terminal Terrestre de Guayaquil via Estación Central Dirección San Pablo, Terminal San Borja, Gran Terminal Terrestre Plaza Norte, Tumbes, and Tumbes in around 2d 20h.

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