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How to get fromChile to Guayaquilby plane, bus, or car

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There are 6 ways to get from Chile to Guayaquil by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Antofagasta Airport

    best
    1. Fly from Antofagasta Airport (ANF) to José Joaquín De Olmedo International Airport (GYE)plane plane ANF - GYE
    8h 31m
    $302–726

  2. Bus

    cheapest
    1. Take the bus from Terminal Sur de Santiago to Lima Javier Pradobus bus Lima
    2. Take the bus from Lima Javier Prado to Terminal Terrestre de Guayaquilbus bus Lima
    3d 13h
    $141–271

  3. Bus via Tumbes

    1. Take the bus from Terminal Sur de Santiago to Lima Javier Pradobus bus
    2. Take the bus from Lima Terminal Excluciva to Tumbesbus bus
    3. Take the bus from Tumbes to Terminal Terrestre de Guayaquilbus bus
    3d 8h
    $161–281

  4. Drive  4,715.6 km

    1. Drive from Santiago to Guayaquilcar car 4,715.6 km
    2d 14h
    $663–957

  5. Fly from Comodoro Arturo Merino Benítez International Airport

    1. Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to José Joaquín De Olmedo International Airport (GYE)plane plane SCL - GYE
    8h 20m
    $234–604

  6. Bus via PA448-Avenida Matta / esq. San Diego

    1. Take the bus from Terminal Sur de Santiago to Lima Javier Pradobus bus
    2. Take the bus from Lima Javier Prado to Tumbesbus bus
    3. Take the bus from Tumbes to Terminal Terrestre de Guayaquilbus bus
    3d 14h
    $173–272

Antofagasta Airport (ANF) to José Joaquín De Olmedo International Airport (GYE) flights

Calendar6Weekly Planes
Duration10h 4mAverage Duration
Ticket$265Cheapest Price
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Comparing Your Travel Options

Map of how to get from Chile to Guayaquil.ExpandLaunch map view
  • Distance: 2,603.4 km
  • Duration: 8h 31m

What companies run services between Chile and Guayaquil, Ecuador?

LATAM Chile and JetSMART fly from Antofagasta Airport (ANF) to José Joaquín De Olmedo International Airport (GYE) 6 times a week. Alternatively, you can take a subway from Universidad de Chile Dirección San Pablo to Terminal Terrestre de Guayaquil via Universidad de Santiago Dirección San Pablo, Terminal Sur de Santiago, Lima Javier Prado, Lima Terminal Excluciva, Tumbes, and Tumbes in around 3d 8h.

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