There are 7 ways to get from Cincinnati to Chicago by taxi, train, bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Taxi, train (Amtrak)
best- Take the taxi from Cincinnati to Centralia Amtraktaxi
- Take the train from Centralia Amtrak to Chicago Union Stationtrain Saluki / ...
5h 58m$177–284Drive 262.3 mi
cheapest- Drive from Cincinnati to Chicagocar 262.3 mi
5h 22m$48–70Taxi, bus
- Take the taxi from Cincinnati to El Rancherito - Mount Vernontaxi
- Take the bus from El Rancherito - Mount Vernon to Chicagobus Querétaro / ...
6h 25m$129–253Drive to Williamson County Regional Airport, fly to Chicago O'Hare International Airport
- Drive from Cincinnati to Williamson County Regional Airport (MWA)car
- Fly from Williamson County Regional Airport (MWA) to Chicago O'Hare International Airport (ORD)plane MWA - ORD
3h 53m$100–244Drive to Evansville, fly to Chicago O'Hare International Airport
- Drive from Cincinnati to Evansville (EVV)car
- Fly from Evansville (EVV) to Chicago O'Hare International Airport (ORD)plane EVV - ORD
4h 21m$50–264Taxi, bus to Lambert–St. Louis International Airport, fly to Chicago Midway International Airport
- Take the taxi from Cincinnati to Mount Vernontaxi
- Take the bus from Mount Vernon to St Louis Bus Stationbus
- Fly from Lambert–St. Louis International Airport (STL) to Chicago Midway International Airport (MDW)plane STL - MDW
5h 40m$137–469Taxi, bus to Lambert–St. Louis International Airport, fly to Chicago O'Hare International Airport
- Take the taxi from Cincinnati to Mount Vernontaxi
- Take the bus from Mount Vernon to St Louis Bus Stationbus
- Fly from Lambert–St. Louis International Airport (STL) to Chicago O'Hare International Airport (ORD)plane STL - ORD
6h 2m$352–809
Williamson County Regional Airport (MWA) to Chicago O'Hare International Airport (ORD) flights
Questions & Answers
The cheapest way to get from Cincinnati to Chicago is to drive which costs $45 - $70 and takes 5h 22m.
The fastest way to get from Cincinnati to Chicago is to drive and fly which takes 3h 53m and costs $100 - $250.
The distance between Cincinnati and Chicago is 297 miles. The road distance is 263.8 miles.
The best way to get from Cincinnati to Chicago without a car is to taxi and train which takes 5h 58m and costs $170 - $290.
It takes approximately 5h 58m to get from Cincinnati to Chicago, including transfers.
Yes, the driving distance between Cincinnati to Chicago is 264 miles. It takes approximately 5h 22m to drive from Cincinnati to Chicago.
There are 1295+ hotels available in Chicago.
What companies run services between Cincinnati, IL, USA and Chicago, IL, USA?
There is no direct connection from Cincinnati to Chicago. However, you can take the taxi to Centralia Amtrak then take the train to Chicago Union Station. Alternatively, you can take the taxi to El Rancherito - Mount Vernon, take the bus to Chicago, take the line 35 bus to 35th/Archer Orange Line Station, walk to 35th/Archer, then take the subway to Harold Washington Library.
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- $55–360
- Website
- united.com
Flights from Lambert–St. Louis International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $45–310
- Website
- aa.com
Flights from Williamson County Regional Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 44m
- When
- Every day
- Estimated price
- $40–280
Flights from Evansville to Chicago O'Hare International Airport
- Ave. Duration
- 2h 3m
- When
- Every day
- Estimated price
- $35–240
Flights from Lambert–St. Louis International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $45–310
- Website
- contouraviation.com
Flights from Williamson County Regional Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- $85–220
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Centralia Amtrak to Chicago Union Station
- Ave. Duration
- 4h 37m
- Frequency
- 3 times a day
- Estimated price
- $80–170
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 888 358 6762
- [email protected]
- Website
- tornadobus.com
Bus from El Rancherito - Mount Vernon to Chicago
- Ave. Duration
- 4h 45m
- Frequency
- Once daily
- Estimated price
- $60–170
- Schedules at
- tornadobus.com
- Adults 11-59
- $60–170
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Mount Vernon to St Louis Bus Station
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- $12–24
- Website
- https://www.greyhound.com/
Bus from Mount Vernon to St Louis Bus Station
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- $12–24
- Website
- https://www.greyhound.com/
- Website
- greyhound.com
Bus from Mount Vernon to St Louis Bus Station
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Schedules at
- greyhound.com
Bus from Mount Vernon to St Louis Bus Station
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Schedules at
- greyhound.com
- Ave. Duration
- 53 min
- Estimated price
- $60–120
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide







