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How to get fromCincinnati to Des Moinesby plane, bus (Flixbus, Greyhound), bus, train, car, or bus (Greyhound)

Find Transport to Des Moines

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There are 7 ways to get from Cincinnati to Des Moines by plane, bus (Flixbus, Greyhound), bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Covington

    best
    1. Fly from Covington (CVG) to Des Moines (DSM)plane plane CVG - DSM
    5h 25m
    $110–574

  2. Bus

    cheapest
    1. Take the bus from Greyhound Station Cincinnati to Indianapolis, INbus bus Cincinnati / ...
    2. Take the bus from Indianapolis Union Station to Des Moinesbus bus Greyhound US0157S
    15h
    $84–200

  3. Bus via Dayton

    1. Take the bus from Cincinnati to Dayton Trotwood Bus Stationbus bus
    2. Take the bus from Dayton Trotwood Bus Station to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Des Moinesbus bus
    14h 30m
    $94–158

  4. Bus, train

    1. Take the bus from Cincinnati to Dayton Trotwood Bus Stationbus bus
    2. Take the bus from Dayton Trotwood Bus Station to Indianapolis Union Stationbus bus
    3. Take the train from Indianapolis to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    5. Take the bus from Galesburg to Des Moinesbus bus
    19h 11m
    $139–308

  5. Drive  573.2 mi

    1. Drive from Cincinnati to Des Moinescar car 573.2 mi
    9h 46m
    $105–152

  6. Drive to Blue Grass Airport, fly

    1. Drive from Cincinnati to Lexington-Airport-LEXcar car
    2. Fly from Blue Grass Airport (LEX) to Des Moines (DSM)plane plane LEX - DSM
    6h 4m
    $99–436

  7. Bus to Dayton, fly

    1. Take the bus from Cincinnati to Dayton Trotwood Bus Stationbus bus
    2. Fly from Dayton (DAY) to Des Moines (DSM)plane plane DAY - DSM
    7h 58m
    $90–409

Cincinnati to Des Moines by bus

Calendar5Weekly Buses
Duration14h 30mAverage Duration
Ticket$94Cheapest Price
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Comparing Your Travel Options

Map of how to get from Cincinnati to Des Moines.ExpandLaunch map view
  • Distance: 523.6 mi
  • Duration: 5h 25m

What companies run services between Cincinnati, OH, USA and Des Moines, IA, USA?

Southwest Airlines, Delta, and two other airlines fly from Covington (CVG) to Des Moines (DSM) hourly. Alternatively, you can take a bus from Cincinnati to Des Moines via Dayton Trotwood Bus Station and Indianapolis Union Station in around 14h 30m.

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