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How to get fromCincinnati to Kirksvilleby bus, train, car, plane, or shuttle

Find Transport to Kirksville

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There are 9 ways to get from Cincinnati to Kirksville by bus, train, car, plane, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train

    best
    1. Take the bus from Cincinnati to Chicago Bus Stationbus bus FlixBus 2514 / ...
    2. Take the train from Chicago Union Station to La Plata Stationtrain train Southwest Chief
    12h 18m
    $243–380

  2. Drive  496.2 mi

    cheapest
    1. Drive from Cincinnati to Kirksvillecar car 496.2 mi
    8h 59m
    $91–131

  3. Bus, train via Indianapolis

    1. Take the bus from Cincinnati to Indianapolisbus bus
    2. Take the train from Indianapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to La Plata Stationtrain train
    16h 19m
    $309–560

  4. Fly Covington to Columbia Regional Airport, shuttle

    1. Fly from Covington (CVG) to Columbia Regional Airport (COU)plane plane CVG - COU
    2. Take a shuttle bus from Columbia to Hy-Vee - Kirksvilleshuttle bus
    8h 31m
    $166–722

  5. Bus, train #2

    1. Take the bus from Cincinnati to Indianapolisbus bus
    2. Take the bus from Indianapolis Union Station to Galesburgbus bus
    3. Take the train from Galesburg Amtrak Station to La Plata Stationtrain train
    13h 30m
    $164–320

  6. Fly Covington to Kirksville Regional Airport

    1. Fly from Covington (CVG) to Kirksville Regional Airport (IRK)plane plane CVG - IRK
    6h 51m
    $216–930

  7. Fly Covington to Chicago Midway International Airport, train

    1. Fly from Covington (CVG) to Chicago Midway International Airport (MDW)plane plane CVG - MDW
    2. Take the train from Chicago Union Station to La Plata Stationtrain train
    9h 50m
    $358–616

  8. Bus to Dayton, fly to Kirksville Regional Airport

    1. Take the bus from Martin Luther King Dr & Jefferson Ave WB to Meijer - Middletownbus bus
    2. Fly from Dayton (DAY) to Kirksville Regional Airport (IRK)plane plane DAY - IRK
    11h 10m
    $168–573

  9. Fly Covington to Burlington Municipal Airport, drive

    1. Fly from Covington (CVG) to Burlington Municipal Airport (BRL)plane plane CVG - BRL
    2. Drive from Burlington Municipal Airport (BRL) to Kirksvillecar car
    8h 32m
    $122–636

Covington (CVG) to Columbia Regional Airport (COU) flights

Calendar66Weekly Planes
Duration5h 29mAverage Duration
Ticket$114Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Cincinnati to Kirksville.ExpandLaunch map view
  • Distance: 605.4 mi
  • Duration: 12h 18m

What companies run services between Cincinnati, OH, USA and Kirksville, MO, USA?

United Airlines, Corporate Flight Management Inc, and two other airlines fly from Covington (CVG) to Kirksville Regional Airport (IRK) 5 times a day.

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