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How to get fromCincinnati to Mayo Clinicby plane, bus (Flixbus), car, or bus

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There are 7 ways to get from Cincinnati to Mayo Clinic by plane, bus (Flixbus), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Covington to Rochester

    best
    1. Fly from Covington (CVG) to Rochester (RST)plane plane CVG - RST
    6h 36m
    $106–512

  2. Bus

    1. Take the bus from Cincinnati to Madisonbus bus FlixBus 2514
    2. Take the bus from Madison to Rochesterbus bus Jefferson 966 / ...
    15h 18m
    $122–191

  3. Drive 632.7 mi

    1. Drive from Cincinnati to Mayo Cliniccar car 632.7 mi
    10h 44m
    $116–167

  4. Fly Covington to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Covington (CVG) to Minneapolis–Saint Paul International Airport (MSP)plane plane CVG - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    6h 26m
    $854–1,554

  5. Bus to Dayton, fly to Rochester

    1. Take the bus from Cincinnati to Dayton Trotwood Bus Stationbus bus
    2. Fly from Dayton (DAY) to Rochester (RST)plane plane DAY - RST
    9h 33m
    $112–529

  6. Bus to Indianapolis, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the bus from Cincinnati to Indianapolisbus bus
    2. Fly from Indianapolis (IND) to Minneapolis–Saint Paul International Airport (MSP)plane plane IND - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    8h 59m
    $590–1,203

  7. Bus via Chicago

    1. Take the bus from Cincinnati Bus Station to Chicago Bus Stationbus bus
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to Rochesterbus bus
    18h 42m
    $146–270

Covington (CVG) to Rochester (RST) flights

Calendar54Weekly Planes
Duration5h 12mAverage Duration
Ticket$90Cheapest Price
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Questions & Answers

Map of how to get from Cincinnati to Mayo Clinic.ExpandLaunch map view
  • Distance: 548.8 mi
  • Duration: 6h 36m

What companies run services between Cincinnati, OH, USA and Mayo Clinic, MN, USA?

Delta, United Airlines, and American Airlines fly from Covington (CVG) to Rochester (RST) every 4 hours. Alternatively, you can take a bus from Cincinnati to Mayo Clinic via Madison and Rochester in around 15h 18m.

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