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How to get fromCincinnati to Mayo Clinicby plane, bus (Flixbus), car, or bus

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There are 5 ways to get from Cincinnati to Mayo Clinic by plane, bus (Flixbus), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Covington to Rochester

    best
    1. Fly from Covington (CVG) to Rochester (RST)plane plane CVG - RST
    6h 47m
    $88–592

  2. Bus to Dayton, fly to Rochester

    cheapest
    1. Take the bus from Cincinnati to Dayton Trotwood Bus Stationbus bus
    2. Fly from Dayton (DAY) to Rochester (RST)plane plane DAY - RST
    9h 7m
    $73–417

  3. Bus

    1. Take the bus from Cincinnati to Madisonbus bus FlixBus 2514
    2. Take the bus from Madison to Rochesterbus bus Jefferson Lines 966
    15h 18m
    $116–180

  4. Drive  632.7 mi

    1. Drive from Cincinnati to Mayo Cliniccar car 632.7 mi
    10h 44m
    $116–167

  5. Fly Covington to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Covington (CVG) to Minneapolis–Saint Paul International Airport (MSP)plane plane CVG - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    6h 27m
    $504–1,154

Cincinnati to Mayo Clinic by bus and foot

Calendar6Weekly Services
Duration15h 18mAverage Duration
Ticket$116Cheapest Price
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Questions & Answers

Map of how to get from Cincinnati to Mayo Clinic.ExpandLaunch map view
  • Distance: 548.8 mi
  • Duration: 6h 47m

What companies run services between Cincinnati, OH, USA and Mayo Clinic, MN, USA?

Delta, American Airlines, and United Airlines fly from Covington (CVG) to Rochester (RST) every 4 hours. Alternatively, you can take a bus from Cincinnati to Mayo Clinic via Madison and Rochester in around 15h 18m.

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