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How to get fromCincinnati to Saint Charlesby bus (Greyhound), car, plane, bus (Flixbus), bus (Greyhound, Flixbus), or bus

Find Transport to Saint Charles

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There are 7 ways to get from Cincinnati to Saint Charles by bus (Greyhound), car, plane, bus (Flixbus), bus (Greyhound, Flixbus), or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Cincinnati to Indianapolisbus bus Bsb 14 / ...
    2. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus Greyhound US0421
    10h 39m
    $74–174

  2. Drive  360.2 mi

    cheapest
    1. Drive from Cincinnati to Saint Charlescar car 360.2 mi
    6h 5m
    $62–89

  3. Fly from Covington

    1. Fly from Covington (CVG) to Lambert–St. Louis International Airport (STL)plane plane CVG - STL
    6h 35m
    $162–876

  4. Bus via Chicago (Flixbus)

    1. Take the bus from Cincinnati to Chicago Bus Stationbus bus FlixBus 2514 / ...
    2. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus FlixBus 2510 / ...
    14h 29m
    $118–169

  5. Bus via Nashville

    1. Take the bus from Covington Bus Stop to Nashville Bus Stationbus bus Greyhound US0135
    2. Take the bus from Nashville Bus Station to St Louis Bus Stationbus bus Greyhound US0186 / ...
    15h 7m
    $118–186

  6. Drive to Louisville International Airport, fly

    1. Drive from Cincinnati to Louisville-Airport-SDFcar car
    2. Fly from Louisville International Airport (SDF) to Lambert–St. Louis International Airport (STL)plane plane SDF - STL
    6h 33m
    $133–650

  7. Bus to John Glenn Columbus International Airport, fly

    1. Take the bus from Cincinnati to Columbusbus bus
    2. Fly from John Glenn Columbus International Airport (CMH) to Lambert–St. Louis International Airport (STL)plane plane CMH - STL
    7h 17m
    $150–715

Covington (CVG) to Lambert–St. Louis International Airport (STL) flights

Calendar135Weekly Planes
Duration4h 47mAverage Duration
Ticket$146Cheapest Price
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Comparing Your Travel Options

Map of how to get from Cincinnati to Saint Charles.ExpandLaunch map view
  • Distance: 414.2 mi
  • Duration: 10h 39m

What companies run services between Cincinnati, OH, USA and Saint Charles, MO, USA?

You can take a bus from Cincinnati to Saint Charles via Cincinnati, Indianapolis Union Station, St Louis Bus Station, CIVIC CENTER station, NORTH HANLEY station, North Hanley Transit Center, and 4375 Rider Trail North Sb in around 10h 39m. Alternatively, Southwest Airlines, United Airlines, and three other airlines fly from Covington (CVG) to Lambert–St. Louis International Airport (STL) hourly.

Airlines
Bus operators

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