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How to get fromCincinnati to Saint Charlesby bus (Flixbus, Greyhound), car, plane, or bus

Find Transport to Saint Charles

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There are 6 ways to get from Cincinnati to Saint Charles by bus (Flixbus, Greyhound), car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via Indianapolis

    best
    1. Take the bus from Cincinnati to Dayton Trotwood Bus Stationbus bus
    2. Take the bus from Dayton Trotwood Bus Station to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus
    10h
    $57–111

  2. Drive 360.2 mi

    1. Drive from Cincinnati to Saint Charlescar car 360.2 mi
    6h 5m
    $66–95

  3. Fly from Covington

    1. Fly from Covington (CVG) to Lambert–St. Louis International Airport (STL)plane plane CVG - STL
    6h 1m
    $606–956

  4. Bus

    1. Take the bus from Cincinnati to Dayton Trotwood Bus Stationbus bus FlixBus N2642
    2. Take the bus from Dayton Trotwood Bus Station to St Louis Bus Stationbus bus Greyhound US0421
    10h 50m
    $57–112

  5. Drive to Louisville International Airport, fly

    1. Drive from Cincinnati to Louisville-Airport-SDFcar car
    2. Fly from Louisville International Airport (SDF) to Lambert–St. Louis International Airport (STL)plane plane SDF - STL
    6h 24m
    $118–632

  6. Bus to John Glenn Columbus International Airport, fly

    1. Take the bus from Cincinnati to Columbusbus bus
    2. Fly from John Glenn Columbus International Airport (CMH) to Lambert–St. Louis International Airport (STL)plane plane CMH - STL
    6h 58m
    $831–943

Cincinnati to Saint Charles by bus and train

Calendar5Weekly Services
Duration10hAverage Duration
Ticket$57Cheapest Price
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Questions & Answers

Map of how to get from Cincinnati to Saint Charles.ExpandLaunch map view
  • Distance: 424.7 mi
  • Duration: 10h

What companies run services between Cincinnati, OH, USA and Saint Charles, MO, USA?

You can take a bus from Cincinnati to 4375 Rider Trail North Sb via Dayton Trotwood Bus Station, Indianapolis Union Station, St Louis Bus Station, CIVIC CENTER station, NORTH HANLEY station, and North Hanley Transit Center in around 10h. Alternatively, Southwest Airlines, United Airlines, and two other airlines fly from Covington (CVG) to Lambert–St. Louis International Airport (STL) hourly.

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