Rome2Rio

How to get fromCincinnati to Saint Charlesby bus (Flixbus, Greyhound), car, plane, bus (Greyhound), or bus

Find Transport to Saint Charles

See all options

There are 7 ways to get from Cincinnati to Saint Charles by bus (Flixbus, Greyhound), car, plane, bus (Greyhound), or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via Dayton

    best
    1. Take the bus from Cincinnati to Dayton Trotwood Bus Stationbus bus
    2. Take the bus from Dayton Trotwood Bus Station to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus
    10h
    $63–104

  2. Bus

    cheapest
    1. Take the bus from Greyhound Station Cincinnati to Indianapolis, INbus bus Cincinnati / ...
    2. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus Greyhound US0421
    10h 30m
    $53–144

  3. Drive  360.2 mi

    1. Drive from Cincinnati to Saint Charlescar car 360.2 mi
    6h 5m
    $66–95

  4. Fly from Covington

    1. Fly from Covington (CVG) to Lambert–St. Louis International Airport (STL)plane plane CVG - STL
    6h 1m
    $606–956

  5. Bus #2

    1. Take the bus from Cincinnati to Dayton Trotwood Bus Stationbus bus FlixBus N2642
    2. Take the bus from Dayton Trotwood Bus Station to St Louis Bus Stationbus bus Greyhound US0421
    11h 10m
    $67–107

  6. Bus to John Glenn Columbus International Airport, fly

    1. Take the bus from Cincinnati to Columbusbus bus
    2. Fly from John Glenn Columbus International Airport (CMH) to Lambert–St. Louis International Airport (STL)plane plane CMH - STL
    6h 58m
    $833–943

  7. Bus to Dayton, fly

    1. Take the bus from Cincinnati to Dayton Trotwood Bus Stationbus bus
    2. Fly from Dayton (DAY) to Lambert–St. Louis International Airport (STL)plane plane DAY - STL
    9h 6m
    $96–501

Cincinnati to Saint Charles by bus and train

Calendar5Weekly Services
Duration10hAverage Duration
Ticket$63Cheapest Price
See schedules

Questions & Answers

Map of how to get from Cincinnati to Saint Charles.ExpandLaunch map view
  • Distance: 424.7 mi
  • Duration: 10h

What companies run services between Cincinnati, OH, USA and Saint Charles, MO, USA?

You can take a bus from Cincinnati to 4375 Rider Trail North Sb via Dayton Trotwood Bus Station, Indianapolis Union Station, St Louis Bus Station, CIVIC CENTER station, NORTH HANLEY station, and North Hanley Transit Center in around 10h. Alternatively, Southwest Airlines, United Airlines, and two other airlines fly from Covington (CVG) to Lambert–St. Louis International Airport (STL) hourly.

Airlines
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers