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How to get fromCincinnati to Saint Charlesby bus (Greyhound), car, plane, bus, train, or bus (Flixbus)

Find Transport to Saint Charles

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There are 7 ways to get from Cincinnati to Saint Charles by bus (Greyhound), car, plane, bus, train, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Cincinnati to Indianapolisbus bus Bsb 14 / ...
    2. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus Greyhound US0421
    10h 39m
    $74–169

  2. Drive  360.2 mi

    cheapest
    1. Drive from Cincinnati to Saint Charlescar car 360.2 mi
    6h 5m
    $62–89

  3. Fly from Covington

    1. Fly from Covington (CVG) to Lambert–St. Louis International Airport (STL)plane plane CVG - STL
    6h 35m
    $162–876

  4. Bus, train

    1. Take the bus from Cincinnati to Lafayette Bus Stopbus bus
    2. Take the bus from Lafayette Amtrak Station to Chicago Union Stationbus bus
    3. Take the train from Chicago Union Station to St. Louistrain train
    14h 20m
    $222–350

  5. Bus via Chicago (Flixbus)

    1. Take the bus from Cincinnati to Chicago Bus Stationbus bus FlixBus 2514 / ...
    2. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus FlixBus 2510 / ...
    15h 2m
    $116–172

  6. Drive to Louisville International Airport, fly

    1. Drive from Cincinnati to Louisville-Airport-SDFcar car
    2. Fly from Louisville International Airport (SDF) to Lambert–St. Louis International Airport (STL)plane plane SDF - STL
    6h 33m
    $113–520

  7. Bus to John Glenn Columbus International Airport, fly

    1. Take the bus from Cincinnati to Columbusbus bus
    2. Fly from John Glenn Columbus International Airport (CMH) to Lambert–St. Louis International Airport (STL)plane plane CMH - STL
    7h 17m
    $160–765

Covington (CVG) to Lambert–St. Louis International Airport (STL) flights

Calendar130Weekly Planes
Duration4h 47mAverage Duration
Ticket$139Cheapest Price
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Comparing Your Travel Options

Map of how to get from Cincinnati to Saint Charles.ExpandLaunch map view
  • Distance: 414.2 mi
  • Duration: 10h 39m

What companies run services between Cincinnati, OH, USA and Saint Charles, MO, USA?

You can take a bus from Cincinnati to Saint Charles via Cincinnati, Indianapolis Union Station, St Louis Bus Station, CIVIC CENTER station, NORTH HANLEY station, North Hanley Transit Center, and 4375 Rider Trail North Sb in around 10h 39m. Alternatively, Southwest Airlines, United Airlines, and three other airlines fly from Covington (CVG) to Lambert–St. Louis International Airport (STL) hourly.

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Need to know: Greyhound

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